Posted on | Posted on John Murphy | Leave a Comment on Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19

Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19

Authors: MartinDugasa1TanjaGrote-Westrickb1UtaMerledMichaelaFontenaylmAndreas E.KremerhFrankHansesijRichardVollenbergcEvaLorentzenbShilpaTiwari-BecklerdJérômeDucheminlSyrineEllouzelMarcelVetterhJuliaFürsthPhilippSchusterkTobiasBrixaClaudia M.DenkingerfgCarstenMüller-TidoweHartmutSchmidtc…JoachimKühnb1 Highlights Does prior infection with seasonal human coronavirus OC43 protect against critical COVID-19?• Findings: In an international multi-center study inpatients without anti-HCoV OC43 NP antibodies had an increased risk of…[...]

Read More
Posted on | Posted on John Murphy | Leave a Comment on Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19

Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19

Authors: Martin Dugas 1, Tanja Grote-Westrick 2, Uta Merle 3, Michaela Fontenay 4, Andreas E Kremer 5, Frank Hanses 6, Richard Vollenberg 7, Eva Lorentzen 8, Shilpa Tiwari-Heckler 9, Jérôme Duchemin 10, Syrine Ellouze 11, Marcel Vetter 12, Julia Fürst 13, Philipp Schuster 14, Tobias Brix 15, Claudia M Denkinger 16, Carsten Müller-Tidow 17, Hartmut Schmidt 18, Phil-Robin Tepasse 19, Joachim Kühn 20 Abstract Background: The vast majority of COVID-19…[...]

Read More
Posted on | Posted on John Murphy | Leave a Comment on PubChem

PubChem

OC43 Non-structural protein 2a NCBI ProteinQ80872TaxonomyHuman coronavirus OC43DatesModify2021-08-11Create2017-04-15UniProt 1Names and Identifiers 1.1Synonyms Non-structural protein 2a ns2a 32 kDa accessory protein 32 kDa non-structural protein ns2UniProt 1.2Other Identifiers 1.2.1UniProt ID Q80872UniProt…[...]

Read More
Posted on | Posted on John Murphy | Leave a Comment on The OC43 human coronavirus envelope protein is critical for infectious virus production and propagation in neuronal cells and is a determinant of neurovirulence and CNS pathology

The OC43 human coronavirus envelope protein is critical for infectious virus production and propagation in neuronal cells and is a determinant of neurovirulence and CNS pathology

Authors:Jenny K.Stodola1GuillaumeDubois1AlainLe CoupanecMarcDesforgesPierre J.Talbot Highlights Coronavirus structural envelope (E) protein specific motifs involved in protein-protein interaction or in homo-oligomeric ion channel formation are needed for optimal production of recombinant infectious…[...]

Read More
Posted on | Posted on John Murphy | Leave a Comment on OC43 Membrane Protein Science

OC43 Membrane Protein Science

UniProtKB - Q01455 (VME1_CVHOC) EntryPublicationsFeature viewerFeature table FunctionNames & TaxonomySubcellular locationPathology & BiotechPTM / ProcessingExpressionInteractionStructureFamily & DomainsSequenceSimilar proteinsCross-referencesEntry informationMiscellaneous TopBLASTAlignFormatAdd to basketHistory Membrane protein Gene M OrganismHuman coronavirus OC43 (HCoV-OC43)StatusReviewed-Annotation score:-Experimental…[...]

Read More