{"id":1095,"date":"2021-07-26T20:51:22","date_gmt":"2021-07-26T20:51:22","guid":{"rendered":"http:\/\/wp.cov19longhaulfoundation.org\/?p=1095"},"modified":"2021-07-26T20:51:22","modified_gmt":"2021-07-26T20:51:22","slug":"long-covid-syndrome-associated-brain-fog-and-chemofog-luteolin-to-the-rescue","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=1095","title":{"rendered":"Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue"},"content":{"rendered":"\n<p>Authors: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Theoharides+TC&amp;cauthor_id=33847020\">Theoharis C Theoharides<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-1\">1<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-2\">2<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-3\">3<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-4\">4<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Cholevas+C&amp;cauthor_id=33847020\">Christos Cholevas<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Polyzoidis+K&amp;cauthor_id=33847020\">Konstantinos Polyzoidis<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Politis+A&amp;cauthor_id=33847020\">Antonios Politis<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33847020\/#affiliation-6\">6<\/a><\/sup><\/p>\n\n\n\n<p style=\"font-size:24px\">COVID\u201019 leads to severe respiratory problems, but also to long\u2010COVID syndrome associated primarily with cognitive dysfunction and fatigue. Long\u2010COVID syndrome symptoms, especially brain fog, are similar to those experienced by patients undertaking or following chemotherapy for cancer (chemofog or chemobrain), as well in patients with myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) or mast cell activation syndrome (MCAS). The pathogenesis of brain fog in these illnesses is presently unknown but may involve neuroinflammation via mast cells stimulated by pathogenic and stress stimuli to release mediators that activate microglia and lead to inflammation in the hypothalamus. These processes could be mitigated by phytosomal formulation (in olive pomace oil) of the natural flavonoid luteolin.<\/p>\n\n\n\n<p class=\"has-large-font-size\">For More Information: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8250989\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8250989\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: Theoharis C Theoharides\u00a01\u00a02\u00a03\u00a04\u00a05,\u00a0Christos Cholevas\u00a05,\u00a0Konstantinos Polyzoidis\u00a05,\u00a0Antonios Politis\u00a06 COVID\u201019 leads to severe respiratory problems, but also to long\u2010COVID syndrome associated primarily with cognitive dysfunction and fatigue. Long\u2010COVID syndrome symptoms, especially brain [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1096,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59,592],"tags":[],"class_list":["post-1095","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-brain-fog","category-treatments"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/1095","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1095"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/1095\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/1096"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1095"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1095"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1095"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}