{"id":1150,"date":"2021-07-28T16:14:41","date_gmt":"2021-07-28T16:14:41","guid":{"rendered":"http:\/\/wp.cov19longhaulfoundation.org\/?p=1150"},"modified":"2021-07-28T16:14:41","modified_gmt":"2021-07-28T16:14:41","slug":"a-comprehensive-map-of-the-sars-cov-2-genome","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=1150","title":{"rendered":"A comprehensive map of the SARS-CoV-2 genome"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Authors: <strong>Anne Trafton\u00a0<\/strong>|<strong>\u00a0MIT News Office<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:24px\">In early 2020, a few months after the Covid-19 pandemic began, scientists were able to sequence the full genome of SARS-CoV-2, the virus that causes the Covid-19 infection. While many of its genes were already known at that point, the full complement of protein-coding genes was unresolved.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:24px\">Now, after performing an extensive comparative genomics study, MIT researchers have generated what they describe as the most accurate and complete gene annotation of the SARS-CoV-2 genome. In their study, which appears today in&nbsp;<em>Nature Communications<\/em>, they confirmed several protein-coding genes and found that a few others that had been suggested as genes do not code for any proteins.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:24px\">\u201cWe were able to use this powerful comparative genomics approach for evolutionary signatures to discover the true functional protein-coding content of this enormously important genome,\u201d says Manolis Kellis, who is the senior author of the study and a professor of computer science in MIT\u2019s Computer Science and Artificial Intelligence Laboratory (CSAIL) as well as a member of the Broad Institute of MIT and Harvard.<\/p>\n\n\n\n<p class=\"has-large-font-size wp-block-paragraph\">For More Information: <a href=\"https:\/\/news.mit.edu\/2021\/map-sars-cov-2-genome-0511\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/news.mit.edu\/2021\/map-sars-cov-2-genome-0511<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: Anne Trafton\u00a0|\u00a0MIT News Office In early 2020, a few months after the Covid-19 pandemic began, scientists were able to sequence the full genome of SARS-CoV-2, the virus that causes [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1151,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[189,467],"tags":[],"class_list":["post-1150","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genomics","category-proteomics"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/1150","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1150"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/1150\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/1151"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1150"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1150"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1150"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}