{"id":13363,"date":"2025-09-13T18:00:00","date_gmt":"2025-09-13T22:00:00","guid":{"rendered":"https:\/\/cov19longhaulfoundation.org\/?p=13363"},"modified":"2025-09-09T15:47:40","modified_gmt":"2025-09-09T19:47:40","slug":"covid-19-infection-risk-cut-significantly-with-simple-nasal-spray-research-finds","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=13363","title":{"rendered":"COVID-19 infection risk cut &#8216;significantly&#8217; with simple nasal spray, research finds"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Azelastine nasal spray reduces coronavirus infection by two-thirds, researchers find<\/h2>\n\n\n\n<p class=\"has-small-font-size\">\u00a0By\u00a0Angelica Stabile\u00a0Fox News<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><a href=\"https:\/\/www.foxnews.com\/video\/6377837619112\">FDA official announces COVID-19 vaccine mandates are no longer \u2018legally possible\u2019 for healthy subjects<\/a><\/h4>\n\n\n\n<p>Fox News senior medical analyst Dr. Marc Siegel speaks with Food and Drug Administration Commissioner Dr. Marty Makary about policy changes for COVID-19 vaccine mandates on \u2018Special Report.\u2019<a href=\"https:\/\/beyondwords.io\/?utm_source=https%3A%2F%2Fwww.foxnews.com&amp;utm_medium=player&amp;utm_campaign=7893\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/p>\n\n\n\n<p>A new study has discovered another way to potentially&nbsp;<a href=\"https:\/\/www.foxnews.com\/category\/health\/infectious-disease\/coronavirus\" target=\"_blank\" rel=\"noreferrer noopener\">prevent COVID-19.<\/a><\/p>\n\n\n\n<p>Researchers at Saarland University in Germany headed a clinical trial that found a nasal spray could reduce the risk of coronavirus infection by two-thirds.<\/p>\n\n\n\n<p>The&nbsp;<a href=\"https:\/\/www.foxnews.com\/category\/health\/medical-research\" target=\"_blank\" rel=\"noreferrer noopener\">phase 2 study<\/a>, published in JAMA Internal Medicine, ran from March 2023 to July 2024 at Saarland University Hospital.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.foxnews.com\/health\/new-covid-variant-may-cause-razor-blade-throat-heres-what-know\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><u>NEW COVID VARIANT MAY CAUSE &#8216;RAZOR BLADE THROAT&#8217; \u2014 HERE&#8217;S WHAT TO KNOW<\/u><\/strong><\/a><\/p>\n\n\n\n<p>The 450 healthy adult participants were randomly assigned to receive either the azelastine nasal spray or a placebo, three times per day for 56 days.<\/p>\n\n\n\n<p>The researchers conducted SARS-CoV-2 rapid antigen testing twice a week to diagnose infection. People who had symptoms but received negative antigen test results underwent multiple PCR tests for&nbsp;<a href=\"https:\/\/www.foxnews.com\/category\/health\/respiratory-health\" target=\"_blank\" rel=\"noreferrer noopener\">respiratory viruses.<\/a><\/p>\n\n\n\n<p>Azelastine nasal spray could potentially delay COVID-19 infection, according to new research.&nbsp;(iStock)<\/p>\n\n\n\n<p>Among the 227 individuals who received the azelastine nasal spray, rates of confirmed COVID infection were &#8220;significantly lower&#8221; at 2.2%, compared with 6.7% for the placebo group.<\/p>\n\n\n\n<p>The researchers also noted an increase in the period before infection for the people taking azelastine. In these patients, the medication was linked to a lower rate of PCR-confirmed symptomatic infections and fewer confirmed rhinovirus infections (the primary cause of the&nbsp;<a href=\"https:\/\/www.foxnews.com\/category\/health\/respiratory-health\/cold-and-flu\" target=\"_blank\" rel=\"noreferrer noopener\">common cold<\/a>).<\/p>\n\n\n\n<p>Azelastine nasal spray may also help prevent other respiratory viruses, the researchers found.&nbsp;(iStock)<\/p>\n\n\n\n<p>&#8220;In this single-center trial,&nbsp;<a href=\"https:\/\/www.foxnews.com\/category\/health\/healthy-living\/medications\" target=\"_blank\" rel=\"noreferrer noopener\">azelastine nasal spray<\/a>&nbsp;was associated with reduced risk of SARS-CoV-2 respiratory infections,&#8221; the researchers wrote.<\/p>\n\n\n\n<p>Azelastine has been available as an over-the-counter treatment for hay fever, according to a press release from Saarland University, and has previously been suggested to have an anti-viral effect against COVID and other\u00a0<a href=\"https:\/\/www.foxnews.com\/category\/science\/wild-nature\/viruses\" target=\"_blank\" rel=\"noreferrer noopener\">respiratory viruses<\/a>.<a href=\"https:\/\/www.foxnews.com\/apps-products?pid=AppArticleLink\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/p>\n\n\n\n<p>Lead trial researcher Professor Robert Bals, director of the Department of Internal Medicine at Saarland University Medical Center, commented in a statement that the trial has demonstrated azelastine\u2019s impact in a &#8220;real-world setting.&#8221;<\/p>\n\n\n\n<p>Azelastine led to a reduction in the number of PCR-confirmed symptomatic infections, according to the study.&nbsp;(iStock)<\/p>\n\n\n\n<p>&#8220;Azelastine nasal spray could provide an additional, easily accessible prophylactic to complement existing protective measures, especially for vulnerable groups, during periods of high&nbsp;<a href=\"https:\/\/www.foxnews.com\/category\/health\/infectious-disease\" target=\"_blank\" rel=\"noreferrer noopener\">infection rates<\/a>&nbsp;or before traveling,&#8221; he went on.<\/p>\n\n\n\n<p>&#8220;Our results highlight the need for larger, multicenter trials to continue exploring the use of azelastine nasal sprays as an on-demand preventive treatment, and to examine its potential effectiveness against other respiratory pathogens.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Azelastine nasal spray reduces coronavirus infection by two-thirds, researchers find \u00a0By\u00a0Angelica Stabile\u00a0Fox News FDA official announces COVID-19 vaccine mandates are no longer \u2018legally possible\u2019 for healthy subjects Fox News senior [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":13369,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[680,1334,907,1335,477,567,568,592],"tags":[],"class_list":["post-13363","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anosmia","category-azelastine","category-paronosmia","category-pcr","category-qrt-pcr","category-taste-smell","category-taste-smell-disturbance","category-treatments"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/13363","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13363"}],"version-history":[{"count":2,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/13363\/revisions"}],"predecessor-version":[{"id":13365,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/13363\/revisions\/13365"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/13369"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13363"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13363"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}