{"id":1811,"date":"2021-08-11T18:34:21","date_gmt":"2021-08-11T18:34:21","guid":{"rendered":"http:\/\/wp.cov19longhaulfoundation.org\/?p=1811"},"modified":"2021-08-11T18:34:21","modified_gmt":"2021-08-11T18:34:21","slug":"comparative-study-of-hospitalized-children-with-acute-respiratory-distress-syndrome-caused-by-sars-cov-2-and-influenza-virus","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=1811","title":{"rendered":"Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus"},"content":{"rendered":"\n<p>Authors: <a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Xinghua-Liu\">Xinghua Liu<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Wei-Li\">Wei Li<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Bo-Zhang\">Bo Zhang<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Yan-Guo\">Yan Guo<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Zhao-Hu\">Zhao Hu<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Cao-Peng\">Cao Peng<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Xiao-Lei\">Xiao Lei<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Qunying-Luo\">Qunying Luo<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Qiong-Zhang\">Qiong hang<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Wei-Deng\">Wei Deng<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Juanjuan-Wang\">Juanjuan Wang<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Jianqiao-Tang\">Jianqiao Tang<\/a>,\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Yunqiao-Li\">Yunqiao Li<\/a>\u00a0&amp;\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w#auth-Jianying-Chen\">Jianying Chen<\/a>\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/\"><em>BMC Infectious Diseases<\/em><\/a>\u00a0<strong>volume\u00a021<\/strong>, Article\u00a0number:\u00a0412\u00a0(2021)\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"Abs1\">Abstract<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Background<\/strong><\/h3>\n\n\n\n<p style=\"font-size:24px\">Since the outbreak of coronavirus disease 2019 in December 2019, more than 8 million cases have occurred worldwide as of June 16, 2020. However, it is important to distinguish COVID-19 from other respiratory infectious diseases, such as influenza. Here, we comparatively described the clinical characteristics of children with COVID-19 and pediatric patients with influenza.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Methods<\/h3>\n\n\n\n<p style=\"font-size:24px\">In this retrospective, single-center study, we reviewed the electronic medical records of 585 pediatric patients with COVID-19 or influenza in Wuhan Children\u2019s Hospital, China. Clinical and epidemiological characteristics, laboratory findings, and clinical outcomes were comparatively analysed.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Results<\/h3>\n\n\n\n<p style=\"font-size:24px\">The median ages were 6.96\u2009years (IQR, 2\u201310.81) for children with confirmed COVID-19, 2.67\u2009years (IQR, 1.03\u201315.25) for those with influenza A and 3.67\u2009years (IQR, 1.62\u20135.54) for those with influenza B. Fever was a symptom in 84 (34.7%) COVID-19 cases, 132 (70.21%) influenza A cases and 111 (74.50%) influenza B cases. The median length of stay (LOS) was 11 (8\u201315) days for paediatric COVID-19 patients, 4 (3\u20136) days for influenza A patients and 5 (3\u20136) days for influenza B patients. Twenty-six (13.98%) influenza A patients and 18 (12.59%) influenza B patients presented with decreased white blood cell counts, while 13 (5.33%) COVID-19 patients presented with decreased white blood cell counts. Eight (3.28%) COVID-19 patients, 23 (12.71%) influenza A patients and 21 (14.79%) influenza B patients experienced lymphocytopenia. Acute cardiac injury occurred in 18 (7.29%) COVID-19 patients, while 37 (19.68%) influenza A and 27 (18.12%) influenza B patients had acute cardiac injury.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Conclusion<\/h3>\n\n\n\n<p style=\"font-size:24px\">In this study, the illnesses of children with COVID-19 were demonstrated to be less severe than those of pediatric patients with influenza, and COVID-19 patients had milder illness and fewer complications.<\/p>\n\n\n\n<p class=\"has-large-font-size\">For More Information: <a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06068-w<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: Xinghua Liu,\u00a0Wei Li,\u00a0Bo Zhang,\u00a0Yan Guo,\u00a0Zhao Hu,\u00a0Cao Peng,\u00a0Xiao Lei,\u00a0Qunying Luo,\u00a0Qiong hang,\u00a0Wei Deng,\u00a0Juanjuan Wang,\u00a0Jianqiao Tang,\u00a0Yunqiao Li\u00a0&amp;\u00a0Jianying Chen\u00a0BMC Infectious Diseases\u00a0volume\u00a021, Article\u00a0number:\u00a0412\u00a0(2021)\u00a0 Abstract Background Since the outbreak of coronavirus disease 2019 in December [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1812,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[101,149,425,524],"tags":[],"class_list":["post-1811","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19","category-epidemiology","category-pediatric-health","category-severity"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/1811","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1811"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/1811\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/1812"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1811"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1811"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1811"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}