{"id":2278,"date":"2021-08-16T18:44:55","date_gmt":"2021-08-16T18:44:55","guid":{"rendered":"http:\/\/wp.cov19longhaulfoundation.org\/?p=2278"},"modified":"2021-08-16T18:44:55","modified_gmt":"2021-08-16T18:44:55","slug":"body-mass-index-and-severity-fatality-from-coronavirus-disease-2019-a-nationwide-epidemiological-study-in-korea","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=2278","title":{"rendered":"Body mass index and severity\/fatality from coronavirus disease 2019: A nationwide epidemiological study in Korea"},"content":{"rendered":"\n<ol class=\"wp-block-list\" id=\"author-list\"><li>Authors: <a>In Sook Kang\u00a0,<\/a> <a>Kyoung Ae Kong<\/a> Published: June 22, 2021<\/li><\/ol>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/journals.plos.org\/resource\/img\/logo-plos.png\" alt=\"PLOS\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p style=\"font-size:24px\">Obesity has been reported as a risk factor for severe coronavirus disease 2019 (COVID-19) in recent studies. However, the relationship between body mass index (BMI) and COVID-19 severity and fatality are unclear.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Research design and methods<\/h3>\n\n\n\n<p style=\"font-size:24px\">This study included 4,141 COVID-19 patients who were released from isolation or had died as of April 30, 2020. This nationwide data was provided by the Korean Centers for Disease Control and Prevention Agency. BMI was categorized as follows; &lt; 18.5 kg\/m<sup>2<\/sup>, 18.5\u201322.9 kg\/m<sup>2<\/sup>, 23.0\u201324.9 kg\/m<sup>2<\/sup>, 25.0\u201329.9 kg\/m<sup>2<\/sup>, and \u2265 30 kg\/m<sup>2<\/sup>. We defined a fatal illness if the patient had died.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Results<\/h3>\n\n\n\n<p style=\"font-size:24px\">Among participants, those with a BMI of 18.5\u201322.9 kg\/m<sup>2<\/sup>\u00a0were the most common (42.0%), followed by 25.0\u201329.9 kg\/m<sup>2<\/sup>\u00a0(24.4%), 23.0\u201324.9 kg\/m<sup>2<\/sup>\u00a0(24.3%), \u2265 30 kg\/m<sup>2<\/sup>\u00a0(4.7%), and &lt; 18.5 kg\/m<sup>2<\/sup>\u00a0(4.6%). In addition, 1,654 (41.2%) were men and 3.04% were fatalities. Multivariable analysis showed that age, male sex, BMI &lt; 18.5 kg\/m<sup>2<\/sup>, BMI \u2265 25 kg\/m<sup>2<\/sup>, diabetes mellitus, chronic kidney disease, cancer, and dementia were independent risk factors for fatal illness. In particular, BMI &lt; 18.5 kg\/m<sup>2<\/sup>\u00a0(odds ratio [OR] 3.97, 95% CI 1.77\u20138.92), 25.0\u201329.9 kg\/m<sup>2<\/sup>\u00a0(2.43, 1.32\u20134.47), and \u2265 30 kg\/m<sup>2<\/sup>\u00a0(4.32, 1.37\u201313.61) were found to have higher ORs than the BMI of 23.0\u201324.9 kg\/m<sup>2<\/sup>\u00a0(reference). There was no significant difference between those with a BMI of 18.5\u201322.9 kg\/m<sup>2<\/sup>\u00a0(1.59, 0.88\u20132.89) and 23.0\u201324.9 kg\/m<sup>2<\/sup>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Conclusions<\/h3>\n\n\n\n<p style=\"font-size:24px\">This study demonstrated a non-linear (U-shaped) relationship between BMI and fatal illness. Subjects with a BMI of &lt; 18.5 kg\/m<sup>2<\/sup>\u00a0and those with a BMI \u2265 25 kg\/m<sup>2<\/sup>\u00a0had a high risk of fatal illness. Maintaining a healthy weight is important not only to prevent chronic cardiometabolic diseases, but also to improve the outcome of COVID-19.<\/p>\n\n\n\n<p class=\"has-large-font-size\">For More Information: <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0253640\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0253640<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: In Sook Kang\u00a0, Kyoung Ae Kong Published: June 22, 2021 Abstract Obesity has been reported as a risk factor for severe coronavirus disease 2019 (COVID-19) in recent studies. However, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[670,724,101,333,524],"tags":[],"class_list":["post-2278","post","type-post","status-publish","format-standard","hentry","category-age-related-outcome","category-body-mass-index","category-covid-19","category-mortality-morbidity","category-severity"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/2278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2278"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/2278\/revisions"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}