{"id":2481,"date":"2021-08-20T12:52:48","date_gmt":"2021-08-20T12:52:48","guid":{"rendered":"http:\/\/wp.cov19longhaulfoundation.org\/?p=2481"},"modified":"2021-08-20T12:52:48","modified_gmt":"2021-08-20T12:52:48","slug":"delta-is-surging-but-is-another-variant-on-the-way-heres-what-to-know-about-lambda","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=2481","title":{"rendered":"Delta is surging, but is another variant on the way? Here\u2019s what to know about lambda"},"content":{"rendered":"\n<p>Ben Sessoms, The Charlotte Observer\u00a0\u00a0<\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<p style=\"font-size:22px\">The delta variant is by far the dominant strain of the coronavirus in North Carolina and the rest of the country, but experts say there are also other variants to watch.<\/p>\n\n\n\n<p style=\"font-size:22px\">Before delta,&nbsp;<a href=\"https:\/\/www.newsobserver.com\/news\/coronavirus\/article252903578.html\" target=\"_blank\" rel=\"noreferrer noopener\">there was alpha, beta and gamma<\/a>.<\/p>\n\n\n\n<p style=\"font-size:22px\">Now there is another, lambda, which is primarily spreading in South America.<\/p>\n\n\n\n<p style=\"font-size:22px\">Some cases of lambda&nbsp;<a href=\"https:\/\/www.khou.com\/article\/news\/health\/coronavirus\/houston-covid-cases-increasing-delta-and-lambda-variant\/285-c8db586b-7673-4405-9c7a-11386c3782e8\" target=\"_blank\" rel=\"noreferrer noopener\">were found at a Houston hospital last month<\/a>, according to KHOU11.<\/p>\n\n\n\n<p style=\"font-size:22px\">Other&nbsp;<a href=\"https:\/\/www.dallasnews.com\/news\/2021\/08\/16\/5-things-to-know-about-the-lambda-variant-and-its-arrival-in-dallas\/?fbclid=IwAR3xyPpQHDoEnitYeR7qvpnuQd-aADWdKNeZ-wETQFY3i35jAP7xqBhM-Ac\" target=\"_blank\" rel=\"noreferrer noopener\">cases were found in Dallas<\/a>&nbsp;earlier this week, according to The Dallas Morning News.<\/p>\n\n\n\n<p style=\"font-size:22px\">But is it spreading in North Carolina? And does the vaccine protect against it?<\/p>\n\n\n\n<p style=\"font-size:22px\">Here is what you need to know about the lambda variant.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What is lambda?<\/h3>\n\n\n\n<p style=\"font-size:22px\">The lambda variant, or C.37, is a mutation of the original strain of SARS-CoV-2, the virus that causes COVID-19.<\/p>\n\n\n\n<p style=\"font-size:22px\">It first emerged in Peru back in December. Since then,&nbsp;<a href=\"https:\/\/cov-lineages.org\/lineage.html?lineage=C.37\" target=\"_blank\" rel=\"noreferrer noopener\">over 1,200 cases of it have been found&nbsp;<\/a>there. In Chile, over 1,400 have been reported.<\/p>\n\n\n\n<p style=\"font-size:22px\">The World Health Organization recognizes it as a variant of interest, meaning that it\u2019s capable of causing significant community transmission.<\/p>\n\n\n\n<p style=\"font-size:22px\">It\u2019s a step below a variant of concern which includes alpha, beta, gamma and delta, which have been shown to increase transmissibility and have had a significant effect on public health, according to WHO.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Is it spreading in NC?<\/h3>\n\n\n\n<p style=\"font-size:22px\">Among all the sequenced coronavirus samples nationwide, only 810 have been found to be lambda.<\/p>\n\n\n\n<p style=\"font-size:22px\">By comparison, over 86,000 have been found to be delta.<\/p>\n\n\n\n<p style=\"font-size:22px\">Due to testing limitations, only a fraction of viruses are sequenced, but&nbsp;<a href=\"https:\/\/www.newsobserver.com\/news\/coronavirus\/article252926233.html\" target=\"_blank\" rel=\"noreferrer noopener\">officials are still confident they\u2019re an accurate overall representation<\/a>&nbsp;of variants among infections, The News &amp; Observer previously reported.<\/p>\n\n\n\n<p style=\"font-size:22px\">The latest data from the Centers for Disease Control and Prevention doesn\u2019t list lambda as a variant of concern in North Carolina.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Is it vaccine resistant?<\/h3>\n\n\n\n<p style=\"font-size:22px\">Dr. David Wohl, infectious disease specialist at the UNC-Chapel Hill, said the lambda variant is potentially concerning because in theory, the COVID-19 vaccines are not as effective against it.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cThere\u2019s indications that the antibodies from people who\u2019ve been vaccinated do not neutralize lambda as well as they neutralize other variants,\u201d Wohl said. \u201cThat\u2019s the concern with lambda is that in laboratory tests, there may be diminished activity. It still works but not as avidly.\u201d<\/p>\n\n\n\n<p style=\"font-size:22px\">But some lab tests also show diminished vaccine effectiveness with delta, he said, yet in people, where delta is spreading much more rapidly than lambda, it\u2019s a different story.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cIf [the vaccine] didn\u2019t work against delta, we would have our hospital and ICU filled with people who got Moderna, Pfizer and J&amp;J,\u201d Wohl said. \u201cAnd we\u2019re not seeing that.\u201d<\/p>\n\n\n\n<p style=\"font-size:22px\">According to state officials,&nbsp;<a href=\"https:\/\/www.newsobserver.com\/news\/local\/article253574904.html\" target=\"_blank\" rel=\"noreferrer noopener\">over 90% of people hospitalized with COVID-19, and almost all ICU patients, are unvaccinated<\/a>.<\/p>\n\n\n\n<p style=\"font-size:22px\">Dr. Mandy Cohen, secretary of the N.C. Department of Health and Human Services, said at a press conference Wednesday that&nbsp;<a href=\"https:\/\/www.newsobserver.com\/news\/coronavirus\/article253558329.html\" rel=\"noreferrer noopener\" target=\"_blank\">those who are unvaccinated are four times more likely to get COVID<\/a>.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cWe know that the vaccine works against all these variants. It does. It\u2019s all relative, though,\u201d Wohl said. \u201cCompared to other variants we\u2019re seeing in some of these lab tests, there are some concerns that maybe the antibodies produced by the vaccine aren\u2019t as good against some of these newer variants.\u201d<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">How does lambda compare to delta?<\/h3>\n\n\n\n<p style=\"font-size:22px\">Cohen said at a press conference late last month that delta is three times as contagious as the original strain.<\/p>\n\n\n\n<p style=\"font-size:22px\">Wohl said data is limited<\/p>\n\n\n\n<p style=\"font-size:22px\">but given how much delta has spread in the past month, he\u2019s not sure if lambda is as transmissible right now.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cIn order for lambda to become the predominant virus, it has to outpace delta. It has to have some advantage over delta,\u201d he explained. \u201cOtherwise, you won\u2019t be able to continue to spread because there\u2019s no niche for it.\u201d<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cI think we would have seen lambda spread already, if it really was able to be fitter than delta,\u201d he said.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Is a vaccine resistant variant coming?<\/h3>\n\n\n\n<p style=\"font-size:22px\">Given that so many remain unvaccinated, there hasn\u2019t been an evolutionary need for a variant to evolve that\u2019s able to cause severe illness in those vaccinated, Wohl said.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cYou really need a pressure to be applied to a virus in order to see it mutate,\u201d he said.<\/p>\n\n\n\n<p style=\"font-size:22px\">The delta variant is spreading because of low vaccination rates and because it can infect vaccinated people, though a vast majority of cases are mild.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cRight now in our country, given how many people are unvaccinated, there\u2019s a little bit less pressure actually on the virus to become resistant to the vaccines because there\u2019s plenty of easy pickings of people who are not vaccinated,\u201d Wohl explained.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cMaybe that\u2019s kind of a silver lining. That it prevents us from getting infected \u2014 and this is all theoretical \u2014 with a variant that could be worse,\u201d he said.<\/p>\n\n\n\n<p style=\"font-size:22px\">Still, Wohl urged the unvaccinated to get their shots because the vaccine protects against severe disease and death.<\/p>\n\n\n\n<p style=\"font-size:22px\">And even in countries with higher vaccination rates, vaccinations are still working and vaccine-resistant variants are not emerging, he said.<\/p>\n\n\n\n<p style=\"font-size:22px\">If a vaccine-resistant variant does emerge, Wohl said the mRNA technology in the Pfizer and Moderna vaccines can be adjusted quickly to compensate for such a mutation in the virus.<\/p>\n\n\n\n<p style=\"font-size:22px\">\u201cI don\u2019t think we\u2019re going to see a truly vaccine-resistant variant for a long time, and by that time, I think we\u2019re going to be better prepared,\u201d Wohl said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ben Sessoms, The Charlotte Observer\u00a0\u00a0 The delta variant is by far the dominant strain of the coronavirus in North Carolina and the rest of the country, but experts say there [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2482,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[110,275,375,607],"tags":[],"class_list":["post-2481","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-delta","category-lambda","category-news-of-the-day","category-vaccine-news"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/2481","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2481"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/2481\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/2482"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2481"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2481"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2481"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}