{"id":7385,"date":"2023-09-20T11:39:35","date_gmt":"2023-09-20T11:39:35","guid":{"rendered":"http:\/\/www.cov19longhaulfoundation.org\/?p=7385"},"modified":"2023-09-20T11:39:35","modified_gmt":"2023-09-20T11:39:35","slug":"new-study-detects-spike-protein-6-months-after-covid-19-vaccination","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=7385","title":{"rendered":"New Study Detects Spike Protein 6 Months After COVID-19 Vaccination"},"content":{"rendered":"\n<p>SEP 20, 2023 <em>Authored by Megan Redshaw The Epoch Times\u00a0<\/em><\/p>\n\n\n\n<p><strong>According to the\u00a0<a rel=\"noreferrer noopener\" href=\"https:\/\/www.cdc.gov\/widgets\/micrositeCollectionViewerMed\/index.html?chost=www.brown.edu&amp;cpath=\/emerging-infectious-disease\/covid-19&amp;csearch=&amp;chash=!%2Fdetail%2F403327&amp;ctitle=COVID-19%20%7C%20Emerging%20Infectious%20Disease%20%7C%20Brown%20University&amp;wn=micrositeCollectionViewerMed&amp;wf=\/widgets\/micrositeCollectionViewerMed\/&amp;wid=micrositeCollectionViewerMed1&amp;mMode=widget&amp;mPage=&amp;mChannel=&amp;cdcCollectionid=403305&amp;cdcTheme=theme1&amp;cdcGeotag=%7B%27continent%27:%20%276255149%27,%20%27country%27:%20%276252001%27,%20%27state%27:%20%27%27,%20%27region%27:%20%27%27%20%7D&amp;cdcDataid=404908&amp;chashOptMode=out#!\/detail\/415288\" target=\"_blank\">Centers for Disease Control and Prevention<\/a>\u00a0(CDC), mRNA from COVID-19 vaccines is \u201cbroken down within a few days after vaccination and doesn\u2019t last long in the body\u201d<\/strong>\u2014a position it has adhered to since the pandemic&#8217;s beginning,\u00a0<strong>despite research suggesting otherwise\u00a0(<a rel=\"noreferrer noopener\" href=\"https:\/\/phmpt.org\/wp-content\/uploads\/2022\/03\/125742_S1_M2_26_pharmkin-tabulated-summary.pdf\" target=\"_blank\">pdf<\/a>)<\/strong>. The CDC refers to mRNA as \u201cmessenger RNA,\u201d whereas regulatory documents and Pfizer refer to the mRNA in COVID-19 vaccines as \u201c<a rel=\"noreferrer noopener\" href=\"https:\/\/www.theepochtimes.com\/health\/pfizer-documents-show-covid-19-vaccines-contain-potentially-harmful-modified-rna-not-mrna-5478674\" target=\"_blank\">modified RNA<\/a>.\u201d<em><a href=\"https:\/\/www.zerohedge.com\/s3\/files\/inline-images\/spike.JPG?itok=x8o6K-pt\"><\/a><\/em><\/p>\n\n\n\n<p>Yet&nbsp;<strong>a new study published on Aug. 31 in&nbsp;<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/prca.202300048\" target=\"_blank\" rel=\"noreferrer noopener\">Proteomics Clinical Applications<\/a>&nbsp;found spike protein in the biological fluids of people who received an mRNA COVID-19 vaccine six months after vaccination,<\/strong>&nbsp;suggesting mRNA may be integrated or retranscribed in some cells.<\/p>\n\n\n\n<p>The study group included 20 subjects who received two doses of an mRNA COVID-19 vaccine, 20 who were unvaccinated and tested negative for COVID-19 or antibodies indicating they had previously been infected, and a control group of 20 unvaccinated participants who tested positive for COVID-19.<\/p>\n\n\n\n<p>Researchers then tested to differentiate synthetic spike proteins originating from mRNA vaccines from natural spike proteins in biological fluids, such as blood, urine, saliva, and&nbsp;<a href=\"https:\/\/www.uptodate.com\/contents\/basic-principles-and-technique-of-bronchoalveolar-lavage\" target=\"_blank\" rel=\"noreferrer noopener\">bronchoalveolar lavage fluids<\/a>&nbsp;of study participants and monitored vaccine-induced spike protein following vaccination.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Spike Protein From mRNA Differs&nbsp;from Post-Infection Spike&nbsp;Protein<\/h2>\n\n\n\n<p>According to the study, spike proteins originating from the translation of mRNA vaccines differ from natural spike proteins that circulate in biological fluids post-infection because two proline amino acids replaced the amino acids lysine and valine to help stabilize the synthetic spike generated by vaccination.&nbsp;<strong>This double amino acid variation removed a tryptic digestion site (a necessary part of protein absorption) on the natural spike protein.<\/strong>&nbsp;Because of this, researchers said it is possible to differentiate between natural and synthetic spike protein in biological fluids using tryptic digestion followed by mass spectrometry analysis.<\/p>\n\n\n\n<p>Utilizing these techniques,&nbsp;<strong>researchers detected specific fragments of synthetic spike protein in about 50 percent of subjects who received mRNA vaccines<\/strong>. The synthetic spike protein was detected from 69 to 187 days following vaccination. All samples from the unvaccinated control group were negative, including the 20 individuals who had tested positive after contracting COVID-19.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3 Hypotheses for Persistent Synthetic Spike Protein in Vaccinated<\/h2>\n\n\n\n<p>Based on the results of the study, researchers suggested three possible hypotheses to explain why synthetic spike protein persisted in the vaccinated:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The mRNA from COVID-19 vaccines may be integrated or retranscribed in some cells.<\/li>\n\n\n\n<li><a href=\"https:\/\/www.theepochtimes.com\/health\/covid-19-vaccines-and-boosters-were-never-made-with-mrna-5416427\" target=\"_blank\" rel=\"noreferrer noopener\">Pseudouridines<\/a>&nbsp;at a particular sequence position may induce the formation of a spike protein, although the researchers stated this was a remote possibility.<\/li>\n\n\n\n<li>The mRNA-containing nanoparticles may be picked up by bacteria ordinarily present at the basal level in the blood and produce spike protein.<\/li>\n<\/ul>\n\n\n\n<p>Although researchers said all three hypotheses need further study, they concluded that their initial observations could aid in an individual\u2019s decision about whether to take boosters.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Studies<\/h2>\n\n\n\n<p>In a&nbsp;<a href=\"https:\/\/www.mdpi.com\/2227-9059\/11\/8\/2287\" target=\"_blank\" rel=\"noreferrer noopener\">recently published paper<\/a>&nbsp;in Biomedicines, data show the design of the mRNA COVID-19 vaccines allows uncontrolled biodistribution, durability, and persistent bioavailability of the spike protein inside the body after vaccination.<\/p>\n\n\n\n<p>\u201c<strong>The lipid-nanoparticle matrix permits widespread biodistribution of mRNA gene codes to cells in most or all organs<\/strong>\u201d and could potentially damage tissues and cause disease, researchers concluded.<\/p>\n\n\n\n<p>A study published in November 2021 in the&nbsp;<a href=\"https:\/\/journals.aai.org\/jimmunol\/article\/207\/10\/2405\/234284\/Cutting-Edge-Circulating-Exosomes-with-COVID-Spike\" target=\"_blank\" rel=\"noreferrer noopener\">Journal of Immunology<\/a>&nbsp;found exosomes expressing spike protein 14 days after vaccination with mRNA COVID-19 vaccines. A spike protein increase was observed four months following the second vaccine dose and increased following booster doses.<\/p>\n\n\n\n<p>In a January 2023 study published in the&nbsp;<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/apm.13294\" target=\"_blank\" rel=\"noreferrer noopener\">Journal of Pathology, Microbiology, and Immunology<\/a>, researchers found full-length or traces of SARS-CoV-2 spike mRNA in some patient samples up to 28 days after COVID-19 vaccination, indicating prolonged spike protein production.<\/p>\n\n\n\n<p><strong>A study published in March 2022 in Cell&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8786601\/\" target=\"_blank\" rel=\"noreferrer noopener\">found vaccine mRNA<\/a>&nbsp;in lymph nodes on days 7, 16, and 37 following vaccination, with lower but still appreciable levels at day 60<\/strong>. Immunohistochemical staining for spike antigen in mRNA-vaccinated patient lipid nanoparticles in some individuals showed an abundant amount of spike protein 16 days after the second dose, with spike antigen \u201cstill present as late as 60 days post-second dose,\u201d researchers said.<\/p>\n\n\n\n<p>A Pfizer Japanese&nbsp;<a href=\"https:\/\/archive.org\/details\/pfizer-confidential-translated\" rel=\"noreferrer noopener\" target=\"_blank\">biodistribution study<\/a>&nbsp;showed COVID-19 vaccine spike protein can travel from the injection site through the blood and accumulate in organs and tissues, including the spleen, bone marrow, liver, adrenal glands, and ovaries. Vaccine mRNA was present from the day of vaccination and persisted in the bloodstream for weeks after vaccination.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CDC Says Vaccines Do Not Affect DNA, Despite Conflicting Evidence<\/h2>\n\n\n\n<p>The CDC, in addition to claiming mRNA from COVID-19 vaccines quickly break down within the body, also&nbsp;<a href=\"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/different-vaccines\/how-they-work.html\" target=\"_blank\" rel=\"noreferrer noopener\">states on its website<\/a>&nbsp;that these vaccines \u201cdo not affect or interact with our DNA\u201d\u2014the genetic material contained within the nucleus of cells\u2014because these vaccines do not \u201center the nucleus of the cell.\u201d<\/p>\n\n\n\n<p><strong>The agency says \u201cmessenger RNA\u201d COVID-19 vaccines work by \u201cdelivering instructions (genetical material) to our cells to start building protection\u201d<\/strong>&nbsp;against SARS-CoV-2, and that the body discards all vaccine ingredients after producing an immune response just as it discards \u201cany information cells no longer need.\u201d According to the CDC, this process is a \u201cpart of normal body functioning.\u201d<\/p>\n\n\n\n<p>The current analysis and previous studies challenge this position. A February 2022 study published in&nbsp;<a href=\"https:\/\/www.mdpi.com\/1467-3045\/44\/3\/73\" target=\"_blank\" rel=\"noreferrer noopener\">Current Issues in Molecular Biology<\/a>&nbsp;shows&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK19424\/\" target=\"_blank\" rel=\"noreferrer noopener\">reverse transcription<\/a>&nbsp;of vaccine mRNA into DNA using human liver cell lines. Additional studies have shown RNA from SARS-CoV-2&nbsp;<a href=\"https:\/\/www.pnas.org\/doi\/full\/10.1073\/pnas.2105968118\" target=\"_blank\" rel=\"noreferrer noopener\">can be reverse-transcribed<\/a>&nbsp;and integrated into the genome of cultured human cells\u2014and expressed in patient-derived tissues or by&nbsp;<a href=\"https:\/\/www.mdpi.com\/1999-4915\/15\/3\/629\" target=\"_blank\" rel=\"noreferrer noopener\">virus-infected cells<\/a>.<\/p>\n\n\n\n<p><strong>To date, pharmacokinetic and pharmacodynamic data on mRNA COVID-19 vaccines is limited<\/strong>. Pharmacokinetics&nbsp;is the study of how the body responds to administered substances throughout the entire duration of exposure. Pharmacodynamics assesses the drug\u2019s effect on the body more closely. Understanding how long spike protein is produced by the body and how long it is present in biological tissues&nbsp;<a href=\"https:\/\/www.theepochtimes.com\/health\/conflicting-evidence-of-mrna-technology-raises-serious-concerns-about-rush-for-use-in-new-vaccine-development-5480328\" target=\"_blank\" rel=\"noreferrer noopener\">could explain<\/a>&nbsp;the unprecedented number of adverse events that appear to be associated with the spike protein produced by vaccines.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>SEP 20, 2023 Authored by Megan Redshaw The Epoch Times\u00a0 According to the\u00a0Centers for Disease Control and Prevention\u00a0(CDC), mRNA from COVID-19 vaccines is \u201cbroken down within a few days after [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":7386,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[761,126,337,541,974,607,608],"tags":[],"class_list":["post-7385","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-concerns","category-dna","category-mrna","category-spike-protein","category-vaccine-long-term-safety","category-vaccine-news","category-vaccine-safety"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/7385","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7385"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/7385\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7385"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7385"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7385"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}