{"id":7791,"date":"2024-11-07T06:00:00","date_gmt":"2024-11-07T11:00:00","guid":{"rendered":"http:\/\/www.cov19longhaulfoundation.org\/?p=7791"},"modified":"2024-07-11T06:36:51","modified_gmt":"2024-07-11T11:36:51","slug":"pfizer-biontech-sars-cov-2-vaccine-as-a-potential-trigger-for-the-development-of-narcolepsy-a-case-report","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=7791","title":{"rendered":"Pfizer\/BioNTech SARS-CoV-2 vaccine as a potential trigger for the development of narcolepsy: a case report"},"content":{"rendered":"\n<p class=\"has-small-font-size\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mahamid+A&amp;cauthor_id=35733336\">Ala Mahamid<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35733336\/#full-view-affiliation-1\">1<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Bornstein+RJ&amp;cauthor_id=35733336\">Robyn Jacob Bornstein<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35733336\/#full-view-affiliation-2\">2<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Amir+H&amp;cauthor_id=35733336\">Hagay Amir<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35733336\/#full-view-affiliation-3\">3<\/a><\/sup> PMID:\u00a0<strong>35733336<\/strong> PMCID:\u00a0<a rel=\"noreferrer noopener\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc9516586\/\" target=\"_blank\">PMC9516586<\/a> DOI:\u00a0<a rel=\"noreferrer noopener\" href=\"https:\/\/doi.org\/10.5664\/jcsm.10134\" target=\"_blank\">10.5664\/jcsm.10134<\/a>  J Clin Sleep Med.\u00a02022 Oct 1;18(10):2503-2506.\u00a0doi: 10.5664\/jcsm.10134.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p>Narcolepsy is a rare condition in Israel. Currently, the incidence of narcolepsy following SARS-CoV-2 vaccination in Israel is unknown. We are reporting a case report of a 51-year-old woman of Ashkenazi Jewish descent who was evaluated for complaints of excessive daytime sleepiness and relative functional decline that immediately followed receipt of the Pfizer\/BioNTech SARS-CoV-2 vaccination. Evaluation of patient-reported data with polysomnography and multiple sleep latency test was consistent with narcolepsy with cataplexy, meeting the criteria for a diagnosis of type 1 narcolepsy. Further investigation included human leukocyte antigen testing. Prior studies have demonstrated genetic, immunological, and environmental factors associated with narcolepsy following other vaccinations. This case is a valuable contribution to the literature as there are no prior reports of type 1 narcolepsy following SARS-CoV-2 vaccination in the State of Israel.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ala Mahamid\u00a01,\u00a0Robyn Jacob Bornstein\u00a02,\u00a0Hagay Amir\u00a03 PMID:\u00a035733336 PMCID:\u00a0PMC9516586 DOI:\u00a010.5664\/jcsm.10134 J Clin Sleep Med.\u00a02022 Oct 1;18(10):2503-2506.\u00a0doi: 10.5664\/jcsm.10134. Abstract Narcolepsy is a rare condition in Israel. Currently, the incidence of narcolepsy following SARS-CoV-2 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":10106,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[761,887,536,972,607],"tags":[],"class_list":["post-7791","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-concerns","category-narcolepsy","category-sleep","category-vaccine-enhanced-disease","category-vaccine-news"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/7791","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7791"}],"version-history":[{"count":1,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/7791\/revisions"}],"predecessor-version":[{"id":10105,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/7791\/revisions\/10105"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/10106"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}