{"id":945,"date":"2021-07-21T19:15:53","date_gmt":"2021-07-21T19:15:53","guid":{"rendered":"http:\/\/wp.cov19longhaulfoundation.org\/?p=945"},"modified":"2021-07-21T19:15:53","modified_gmt":"2021-07-21T19:15:53","slug":"the-hallmarks-of-covid-19-disease","status":"publish","type":"post","link":"https:\/\/cov19longhaulfoundation.org\/?p=945","title":{"rendered":"The hallmarks of COVID-19 disease"},"content":{"rendered":"\n<p>Authors: <a>Daolin Tang\u00a0,Paul Comish,Rui Kang\u00a0<\/a><\/p>\n\n\n\n<p style=\"font-size:24px\">Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a severe threat to public health and safety. Analysis of the genetic tree suggests that SARS-CoV-2 belongs to the same\u00a0<em>Betacoronavirus<\/em>\u00a0group as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Although the route for viral transmission remains a mystery, SARS-CoV-2 may have originated in an animal reservoir, likely that of bat. The clinical features of COVID-19, such as fever, cough, shortness of breath, and fatigue, are similar to those of many acute respiratory infections. There is currently no specific treatment for COVID-19, but antiviral therapy combined with supportive care is the main strategy. Here, we summarize recent progress in understanding the epidemiological, virologic, and clinical characteristics of COVID-19 and discuss potential targets with existing drugs for the treatment of this emerging zoonotic disease.<\/p>\n\n\n\n<p class=\"has-large-font-size\">For More Information: <a href=\"https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371%2Fjournal.ppat.1008536\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371%2Fjournal.ppat.1008536<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: Daolin Tang\u00a0,Paul Comish,Rui Kang\u00a0 Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":883,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[101,149,289,549],"tags":[],"class_list":["post-945","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19","category-epidemiology","category-long-haul-disease","category-standards-of-care"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/945","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=945"}],"version-history":[{"count":0,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/945\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/883"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=945"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=945"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=945"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}