Ingrid\u00a0Didriksson,\u00a0Attila\u00a0Frigyesi,\u00a0Martin\u00a0Sp\u00e5ngfors,\u00a0et. al.<\/p>\n\n\n\n
Background<\/strong> Long-term outcomes after critical COVID-19 have not been sufficiently studied. This study aimed to describe changes in functional outcome and health-related quality of life (HRQoL) assessed at 3 and 12 months in a cohort of critically ill COVID-19 survivors. A secondary aim was to investigate factors associated with good functional outcome and HRQoL at 12 months.<\/p>\n\n\n\n Methods<\/strong> This prospective multicentre cohort study included critically ill COVID-19 patients admitted to six intensive care units in Sweden between May 2020 and May 2021. Surviving patients were invited to face-to-face follow-ups at 3 and 12 months. A good functional outcome was a Glasgow outcome scale extended \u22657. HRQoL was assessed by the physical and mental component summary of the SF-36v2\u00ae, with T-scores \u226545 representing a good HRQoL. Factors associated with good functional outcome and HRQoL at 12 months were explored by multivariable logistic regression.<\/p>\n\n\n\n Results<\/strong> A good functional outcome was found in 93\/264 (35%) and 138\/217 (64%) of survivors at 3 and 12 months, respectively. There was a significant improvement in the SF-36v2\u00ae Physical component summary (PCS) between 3 and 12 months (mean 40 versus 44, p<<\/em>0.001). The SF-36v2\u00ae Mental component summary (MCS) was within the normal range at 3 months, with no significant change at 12 months (mean 46 versus 48, p=0.05). Older age was associated with a good functional outcome. Low clinical frailty and absence of diabetes mellitus were associated with a good physical HRQoL. A shorter duration of mechanical ventilation was associated with a good outcome for all three outcome measures.<\/p>\n\n\n\n Conclusion<\/strong> Between 3 and 12 months, functional outcome and physical aspects of HRQoL significantly improved, indicating continued recovery up to at least one year after critical COVID-19. Low frailty, less comorbidity, and shorter duration of mechanical ventilation were associated with better long-term outcomes, while old age was associated with better functional outcome.<\/p>\n","protected":false},"excerpt":{"rendered":" Ingrid\u00a0Didriksson,\u00a0Attila\u00a0Frigyesi,\u00a0Martin\u00a0Sp\u00e5ngfors,\u00a0et. al. Abstract Background Long-term outcomes after critical COVID-19 have not been sufficiently studied. This study aimed to describe changes in functional outcome and health-related quality of life (HRQoL) assessed at […]<\/p>\n","protected":false},"author":2,"featured_media":9453,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[289,290],"tags":[],"class_list":["post-9451","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-haul-disease","category-long-term-effects"],"_links":{"self":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/9451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9451"}],"version-history":[{"count":1,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/9451\/revisions"}],"predecessor-version":[{"id":9452,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/posts\/9451\/revisions\/9452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=\/wp\/v2\/media\/9453"}],"wp:attachment":[{"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cov19longhaulfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}