John Murphy, CEO The COVID-19 Long-haul Foundation Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 2019 (COVID-19), is a pleiotropic pathogen with profound effects […]
SARS-CoV-2–Associated Injury to Human Epithelial Tissues
Authors: John Murphy, M.D., MPH, DPH. ,Affiliations: President COVID-19 Long-haul FoundationAbstract: 250 words Abstract BackgroundSARS-CoV-2 infection produces multisystem disease with prominent epithelial involvement extending beyond the respiratory tract. Increasing evidence […]
COVID-19 and the Etiology of Skin Breakdown: Genomic Mechanisms, Clinical Diagnosis, Variations, Treatment, and Outcomes
The global impact of COVID-19 has extended far beyond its respiratory origins, revealing a complex spectrum of systemic manifestations. Among these, dermatologic involvement has emerged as both a diagnostic clue […]
Cutaneous Consequences of COVID-19: Disruption of the Dermis, Epidermis, and Vascular Matrix
John Murphy, The COVID 19 Long-haul Foundation Abstract SARS-CoV-2, the virus responsible for COVID-19, is primarily known for its respiratory and systemic effects. However, its impact on the skin—particularly the […]
Nails and COVID‐19 – A comprehensive review of clinical findings and treatment
Uwe Wollina 1,✉, Jean Kanitakis 2, Robert Baran 3, PMCID: PMC8420555 PMID: 34398500 Abstract The SARS‐CoV‐2 infection, responsible for COVID‐19, has raised the interest for infection‐associated muco‐cutaneous symptoms. While dermatologic symptoms in general gained an increasing awareness, […]
Unveiling the Connections Between Melanoma Differentiation-Associated Gene 5 (MDA5)-Positive Dermatomyositis and Its Potential Association With COVID-19: A Report of Two Cases
Temitope B. Abegunde • Christophe Persad • Sojibuchi Ojule • Jane Colgan • Margaret Duncan, 2024DOI: 10.7759/cureus.65016 Abstract Dermatomyositis is a rare inflammatory condition affecting the skin, muscles, and joints. This series of anti-melanoma differentiation-associated gene 5 (anti-MDA5) autoantibody-positive […]
Three years on, COVID-19 and the skin: long-term impacts, emerging trends and clinical practice
Esther E Freeman, Ignacio Garcia-Doval, Luigi Naldi, Roderick J Hay British Journal of Dermatology, Volume 189, Issue 1, July 2023, Pages 1–, https://doi.org/10.1093/bjd/ljad131 In early 2020 there were reports of a new and potentially fatal […]
IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo
Shreya Ghimire, Biyun Xue, Kun Li, Ryan M Gannon, et. al.doi: https://doi.org/10.1101/2024.07.03.60194 Abstract Treatments available to prevent progression of virus-induced lung diseases, including coronavirus disease 2019 (COVID-19) are of limited benefit once respiratory failure occurs. The efficacy of approved […]
SARS-CoV-2 particles promote airway epithelial differentiation and ciliation
Julian Gonzalez-Rubio1 Vu Thuy Khanh Le-Trilling2 Lea Baumann1 Maria Cheremkhina1 Hannah Kubiza1 Anja E. Luengen1,3 Sebastian Reuter3 Christian Taube3 Stephan Ruetten4 Daniela Duarte Campos5 Christian G. Cornelissen1,6 Mirko Trilling2 Anja Lena Thiebes1, Front. Bioeng. Biotechnol., 02 November 2023 Sec. Tissue Engineering and […]
SARS-CoV-2 particles promote airway epithelial differentiation and ciliation
Julian Gonzalez-Rubio1* Vu Thuy Khanh Le-Trilling2 Lea Baumann1 Maria Cheremkhina1 Hannah Kubiza1 Anja E. Luengen1, 3 Sebastian Reuter3 Christian Taube3 Stephan Ruetten4 Daniela Duarte Campos5 Christian Cornelissen6 Mirko Trilling2 Anja Lena Thiebes1* Front. Bioeng. Biotechnology. , Sec. Tissue Engineering and Regenerative Medicine, […]