John Murphy, CEO The Covid Long-haul foundation. Introduction The enduring psychiatric sequelae of SARS-CoV-2 infection remain a defining, yet insufficiently understood, public health challenge of the COVID-19 pandemic. Long-COVID —…[...]
Read More
I. Persistent Cytokine-Driven Inflammatory Signaling I.A. IL-6–Centered Inflammatory Axis Interleukin-6 (IL-6) has emerged as one of the most consistently elevated cytokines in Long COVID cohorts, serving as a central node…[...]
Read More
Authors: John Murphy, M.D., MPH, DPH. ,Affiliations: President COVID-19 Long-haul FoundationAbstract: 250 words Abstract BackgroundSARS-CoV-2 infection produces multisystem disease with prominent epithelial involvement extending beyond the respiratory tract. Increasing evidence…[...]
Read More
In A Nutshell The study can’t determine if these brain changes are permanent, progressive, or temporary since it only examined people once Australian researchers scanned 47 people (19 with long…[...]
Read More
Research led by Kiran Thapaliya (Griffith University) Study Shows Structural Differences In COVID Patients Months After Infection, Even Among Those Who ‘Feel Fine’ In A Nutshell The study can’t determine…[...]
Read More
John Murphy, M.D., MPH, DPH, President The Covid-19 Long-haul Foundation Abstract Motor neuron diseases (MNDs) comprise a heterogeneous spectrum of neurodegenerative and immune-mediated disorders characterized by selective vulnerability of upper…[...]
Read More
John Murphy, M.D., MPH, DPH, President COVID-19 Long-haul Foundation Abstract The coronavirus disease 2019 (COVID‑19) pandemic has reshaped the global landscape of infectious diseases in ways that extend far beyond…[...]
Read More
John Murphy, M.D., MPH, DPH, President COVID-19 Long-haul Foundation Abstract Long COVID—also called post-COVID-19 condition or post-acute sequelae of SARS-CoV-2 infection (PASC)—is a multisystem disorder that commonly produces persistent neurological,…[...]
Read More
John Murphy, M.D., MPH, DPH, President COVID-19 Long-haul Foundation Abstract Persistent, debilitating fatigue and exertional intolerance are among the most frequent and disabling features of post-acute sequelae of SARS-CoV-2 infection…[...]
Read More
John Murphy, M.D., MPH, D.P.H., President The COVID19 Long-haul Foundation AbstractA growing body of evidence implicates mitochondrial dysfunction — including depletion of mitochondrial DNA (mtDNA), loss of mitochondrial membrane potential,…[...]
Read More