Dysautonomia / Postural Orthostatic Tachycardia (POTS) / Sleep & Dreams / Sleep Deprivation / Sleep Disturbance / Sleep Latency / Sleep-Wake Disorders Posted on:

When the Lights Go Out: Long COVID, Transient Loss of Consciousness, Sleep Disturbance, and the Unfinished Science of Cerebral Autonomic Dysfunction

John Murphy, CEO The COVID-19 Long haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has increasingly been recognized as a multisystem disorder in which neurological, cardiovascular, […]

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Brain Fog / Clinical Trials / Exercise / Exercise Intolerance / Fatigue / Headache / Long COV / Long-haul Disease / Postural Orthostatic Tachycardia (POTS) / Recover / Sleep Disturbance Posted on:

Long COVID Is Real. The Mystery Is Why It Takes So Many Forms?

Six years after SARS-CoV-2 emerged, researchers are no longer asking whether patients are sick. They are trying to understand why the same infection can leave one person with debilitating fatigue, […]

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Depression & Mental Health / Dysautonomia / Endothelial Dysfunction / Microvascular damage / Microvascular injury / Neuroinflammation / Sleep Deprivation / Sleep Disturbance Posted on:

Long Covid and Depression: Neuroinflammation, Systemic Illness, and the Persistence of Affective Dysfunction

John Murphy, CEO, The COVID-19 Long-haul Foundation Review Article Abstract Long Covid, or post–COVID-19 condition, has emerged as a heterogeneous, multisystem disorder that may persist for months or years after […]

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Autonomic nervous system disruption / Diagnosis / Diagnostic Framework / Diagnostic Test / Diagnostics / Dysautonomia / Endothelial Dysfunction / Endothelium / Epidemiology / Hormonal Dysregulation / Metabolic Dysregulation / Microvascular damage / Microvascular injury / Mitochondria / Mitochondrial dysfunction / Multidisciplinary Care Pathways / Multisystem Disease / Neuroinflammation / Occupational Therapy / Pathobiological / Physical Therapy / Postural Orthostatic Tachycardia (POTS) / Sleep Disturbance / Systems-Based Model / T-cell / Treatments / Viral persistence Posted on:

Multidisciplinary Care Pathways for Long COVID Fatigue:

A Systems-Based Model Integrating Rehabilitation Medicine, Neuroimmunology, Autonomic Care, and Precision Phenotyping Abstract Background Long COVID, also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one […]

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Autonomic nerves / Autonomic nervous system disruption / Central autonomic network / CNS / Dysautonomia / Endothelium / Etiology / Gastrointestinal / Immune Modulators / Immune System / Immunopathology / Mitochondrial depletion / Orthostatic intolerance / Outcomes / Pathology / Pathophysiology / Postural Orthostatic Tachycardia (POTS) / Sleep Disturbance / Tachycardia / Temperature / Treatments / Vagus Nerve Posted on:

Long COVID and Dysautonomia: Emerging Insights Into Autonomic Dysfunction, Vagal Pathobiology, Neuroimmune Interactions, and Therapeutic Strategies

John Murphy, M.D., M.P.H., D.P.H. CEO COVID Long-haul Foundation Abstract Background Long COVID, also termed Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), is a complex multisystem disorder characterized by persistent symptoms […]

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Actigraphy / Circadian Rhythm / Depression & Mental Health / Endocrine contributors / Idiopathic Hypersomnia / Narcolepsy / Parasomnias / Polysomnography / Psychiatric Disorders / Restless Legs Syndrome / Sleep & Dreams / Sleep Disturbance / Sleep Latency / Sleep-Wake Disorders Posted on:

Sleep Disorders: Etiology, Physiology, Pathology, Clinical Presentation, Diagnostics, Differential Diagnosis, Treatment, and Long-Term Outcomes

A Comprehensive Clinical and Neurobiological Review john Murphy, CEO, The COVID-19 Long-haul Foundation Abstract Sleep disorders comprise a heterogeneous group of conditions characterized by disruption of sleep quantity, quality, timing, […]

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Anxiety / Circadian Rhythm / Cognitive deficit / Depression & Mental Health / Fatigue / Inflammation / Mitochondria / Neurologic Effects / PASC / Sleep & Dreams / Sleep Deprivation / Sleep Disturbance Posted on:

Long COVID and Sleep Disorders: An Emerging Biologic Nexus in Post-Acute Sequelae of SARS-CoV-2 Infection

John Murphy, CEO, COVID-19 Long-haul Foundation Abstract Sleep disturbance has emerged as one of the most prevalent, persistent, and disabling manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), commonly known […]

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