Resonant breathing improves self-reported symptoms and wellbeing in people with Long COVID


Jessica Polizzi, Jenna Tosto-Mancuso, Laura Tabacof, Jamie Wood, David Putrino Introduction: Long COVID involves debilitating symptoms, many of which mirror those observed with dysautonomia, and care must be taken with rehabilitation for autonomic dysfunction to avoid post-exertional malaise/post-exertional symptom exacerbation. Resonant breathing (breathing slowly at a defined rate of breaths per minute) requires less exertion and […]

NIH to open long COVID clinical trials to study sleep disturbances, exercise intolerance, and post exertional malaise


Part of the NIH RECOVER Initiative, trials will test four treatments. The National Institutes of Health (NIH) will launch clinical trials to investigate potential treatments for long-term symptoms after COVID-19 infection, including sleep disturbances, exercise intolerance and the worsening of symptoms following physical or mental exertion known as post-exertional malaise (PEM). The mid-stage trials, part […]

The context of COVID-19 affected the long-term sleep quality of older adults more than SARS-CoV-2 infection


Vanessa Giffoni M. N. P. Peixoto1,2*Lucas Alves Facci3Thiago C. S. Barbalho3, et. al. Frontiers in Medicine, 2024 Introduction: Sleep problems are one of the most persistent symptoms of post-COVID syndrome in adults. However, most recent research on sleep quality has relied on the impact of the pandemic, with scarcely any data for older adults on the […]

Scientists made mini brains and infected them with coronavirus. What they saw could explain Long COVID


Author: Erin Prater Sat, November 5, 202 Yahoo News Just what is COVID capable of doing to the human brain? In a new study published in Molecular Psychiatry, researchers from Sweden and a Harvard-affiliated hospital in Boston tried to find out by creating “brain organoids,” or miniature brains about the size of a pinhead, and infected them with […]

Safety and efficacy of low dose naltrexone in a long covid cohort; an interventional pre-post study.


O’Kelly B 1,2, Vidal L 2, McHugh T 2, et. al. Brain, Behavior, & Immunity – Health, 03 Jul 2022, 24:100485, https://doi.org/10.1016/j.bbih.2022.100485 PMID: 35814187 PMCID: PMC9250701 Abstract  Background Up to 37.7% of patients experience symptoms beyond 12 weeks after infection with SARS-CoV-2. To date care for people with long covid has centred around multidisciplinary rehabilitation, self care and self pacing. No pharmacotherapy has been […]

Sleep and Long COVID—A Review and Exploration of Sleep Disturbances in Post Acute Sequelae of SARS-COV-2 (PASC) and Therapeutic Possibilities


Volume 10, pages 169–180, (2024), Elliott K Lee & R. Robert Auger  Abstract Purpose of Review Post Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2), also known as PASC, and frequently referred to as “long-COVID,” is estimated to afflict over 65 million people worldwide. Sleep disturbances and fatigue are some of the most frequently cited PASC symptoms, and […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches


Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc, et. al. , Frontiers in Medicine The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant proportion of them continue to experience health issues weeks, months […]

Circadian Rhythm, Sleep, and Immune Response and the Fight against COVID-19


Mohammed A. Al-Abri, 1 ,* Saif Al-Yaarubi, 2 and Elias A. Said 3 Oman Med J. 2023 Mar; 38(2): e477. Published online 2023 Mar 31. doi: 10.5001/omj.2023.38 PMCID: PMC10031746 PMID: 37009205 Abstract Sleep is an imperative physiological aspect that plays a vital role in maintaining hormonal and humeral functions of the body and hence a healthy life. Circadian rhythms are daily oscillations in human activities and […]

How did our dreams change when COVID-19 lockdowns ended?


By Yasemin Nicola Sakay Updated 2023 Medical News Today All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our coronavirus hub for the most recent information on COVID-19. Whether it’s a feeling of being trapped, overall frustration, anxiety, or living in an alternate reality, the coronavirus […]

Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments


The causes of long COVID, which disables millions, may come together in the brain and nervous system BY STEPHANI SUTHERLAND Scientific American, 2023 Issue Neuroscience Tara Ghormley has always been an overachiever. She finished at the top of her class in high school, graduated summa cum laude from college and earned top honors in veterinary school. […]