Category: Clots & Bleeds

Posted on | Posted on John Murphy | Leave a Comment on Elevated clotting factor V levels linked to worse outcomes in severe COVID-19 infections

Elevated clotting factor V levels linked to worse outcomes in severe COVID-19 infections

Authors: Jonathan A. Stefely,Bianca B. Christensen,Tasos Gogakos,Jensyn K. Cone Sullivan … See all authors First published: 24 August 2020 https://doi.org/10.1002/ajh.25979 Abstract Coagulopathy causes morbidity and mortality in patients with coronavirus disease 2019 (COVID-19) due…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment

Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment

Authors: Patrick J Lindsay, a Rachel Rosovsky, b Edward A Bittner, c and Marvin G. Chang c ABSTRACT Introduction COVID-19-associated coagulopathy (CAC) is a well-recognized hematologic complication among patients with severe COVID-19 disease, where macro- and micro-thrombosis can…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Factor VIII and Functional Protein C Activity in Critically Ill Patients With Coronavirus Disease 2019: A Case Series

Factor VIII and Functional Protein C Activity in Critically Ill Patients With Coronavirus Disease 2019: A Case Series

Ali Tabatabai 1, Joseph Rabin 2, Jay Menaker 2, Ronson Madathil 3, Samuel Galvagno 4, Ashley Menne 5, Jonathan H Chow 4, Alison Grazioli 6, Daniel Herr 1, Kenichi Tanaka 4, Thomas Scalea 2, Michael Mazzeffi 4Affiliations expand PMID: 32539272 PMCID: PMC7242090 DOI: 10.1213/XAA.0000000000001236 Abstract Critically ill patients with coronavirus disease 2019 (COVID-19) have been observed to…[...]

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Posted on | Posted on John Murphy | Leave a Comment on Whole genome sequencing reveals host factors underlying critical Covid-19

Whole genome sequencing reveals host factors underlying critical Covid-19

Authors: Athanasios Kousathanas, Erola Pairo-Castineira, J. Kenneth BaillieArticle Published: 07 March 2022 nature  articles  article We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the…[...]

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Posted on | Posted on John Murphy | Leave a Comment on 6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records

6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records

Authors: Maxime Taquet, John R Geddes, Masud Husain, Sierra Luciano, Paul J Harrison Summary Background Neurological and psychiatric sequelae of COVID-19 have been reported, but more data are needed to…[...]

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Posted on | Posted on John Murphy | Leave a Comment on COVID‐19‐induced endotheliitis: emerging evidence and possible therapeutic strategies

COVID‐19‐induced endotheliitis: emerging evidence and possible therapeutic strategies

Authors: Eleonora Calabretta, 1 , 12 Jose M. Moraleda, 2 Massimo Iacobelli, 3 Ruben Jara, 4 Israel Vlodavsky, 5 Peter O’Gorman, 6 Antonio Pagliuca, 7 Clifton Mo, 8 Rebecca M. Baron, 9 Alessio Aghemo, 10 , 12 Robert Soiffer, 8 Jawed Fareed, 11 Carmelo Carlo‐Stella, 1 , 12 , * and Paul Richardson 8 , * Br J Haematol. 2021 Apr; 193(1): 43–51.Published online…[...]

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Posted on | Posted on John Murphy | Leave a Comment on The coagulopathy, endotheliopathy, and vasculitis of COVID-19

The coagulopathy, endotheliopathy, and vasculitis of COVID-19

Authors: Toshiaki Iba 1, Jean Marie Connors 2, Jerrold H Levy 3 PMID: 32918567 PMCID: PMC7486586 DOI: 10.1007/s00011-020-01401-6 Abstract Background COVID-19-associated coagulopathy (CAC) characterized by the elevated D-dimer without remarkable changes of other global coagulation markers is associated…[...]

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