John Murphy, CEO The COVID-19 Long-haul Foundation The endothelium, a monolayer of cells lining the interior of blood vessels, is often regarded as a passive conduit for blood flow. Yet […]
Hallucinations in COVID‑19: A Neurological and Clinical Synthesis
John Murphy, M.D., MPH, DPH President Covid-19 long-haul Foundation Coronavirus disease 2019 (COVID‑19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), emerged in late 2019 as a global respiratory […]
Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis […]
Therapeutic Strategies and Clinical Trials in Long COVID: Anticoagulants, Fibrinolytics, Endothelial Support, Immunomodulators, and RECOVER Protocols
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a chronic multisystem condition affecting millions globally. Despite its prevalence, therapeutic options […]
Endothelial Dysfunction and Spike Protein Persistence in Long COVID: Mechanisms, Vulnerabilities, and Clinical Evidence
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms affecting multiple organ systems. Among its most compelling […]
The SARS-CoV-2 Spike Protein: Architecture, Binding Dynamics, and Clearance Evolution Over Five Years
John Murphy, President The COVID Long-haul Foundation Abstract The SARS-CoV-2 spike (S) protein is the principal mediator of viral entry and a key determinant of COVID-19 pathogenesis. This article provides […]
Long Covid: Hormone Imbalances and/or Rather Complex Immune Dysregulations?
Christian A Koch, Journal of the Endocrine Society, Volume 8, Issue 5, May 2024, bvae043, https://doi.org/10.1210/jendso/bvae043 Commentary Approximately 5% of all individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) […]
Endothelial Disruption in Long COVID: Unraveling the Vascular Legacy of SARS-CoV-2
John Murphy, The COVID 19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic multisystem disorder affecting millions worldwide. Among its most […]
Long covid patients are desperate for treatments. These trials may help.
By Richard Sima The Washington Post Five years since the pandemic began, millions of people are still grappling with long COVID, even as new patients are joining their ranks. “Considering […]
❄️ COVID-19 and Chilblains: Unraveling the Dermatologic Puzzle in 2025
🔬 Overview As the COVID-19 pandemic enters its fifth year, dermatological manifestations remain a key area of clinical and immunological inquiry. Among these, chilblains—also known as pernio—have emerged as a […]