John Murphy, M.D., M.P.H., D.P.H. President COVID-19 Long-haul Foundation Abstract Long COVID, also termed post-COVID condition or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one of the most […]
NIH RECOVER Clinical Trials and the First Emergence of Interventional Results in Long COVID Research: A Translational Turning Point
A Scholarly Review for Scientific American (Submission-Style Manuscript) John Murphy, M.D., M.P.H., D.P.H., President, COVID-19 Long-Haul Foundation Abstract The NIH RECOVER Initiative represents the largest coordinated research program investigating post–acute […]
Recognition of Long COVID as a Heterogeneous Post-Infectious Syndrome
Toward a Multisystem Endotype Framework for Post–Acute SARS-CoV-2 Disease John Murphy, M.D., M.P.H., D.P.H. President Covid-19 Long-haul Foundation Abstract Long COVID (post–acute sequelae of SARS-CoV-2 infection, PASC) has emerged as […]
Treatment Landscape in Long COVID Has Expanded Beyond “Supportive Care”
A Mechanism-Driven Reframing of Therapeutic Development in Post–Acute SARS-CoV-2 Disease John Murphy, M.D, M.P.H., D.P.H. President COVID Long-haul Foundation Conceptual Shift and Therapeutic Reclassification ABSTRACT For much of the early […]
Persistent Viral Reservoirs and Immune Dysregulation in Long COVID
John Murphy, M.D., M.P.H., D.P.H., President Covid-19 Long-haul Foundation The Central Discovery Reshaping Post-Acute Sequelae Research Abstract Long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC) has emerged as a multisystem […]
COVID-19 and Edema
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has increasingly been recognized not merely as a viral pneumonic illness but as a diffuse endothelial and […]
Biological Warfare: How a Bat Reproductive Operating System Was Forced Into Humanity
Deep in the mountains of Yunnan Province, China, in the spring of 2012, six men walked into an abandoned copper mine to clear bat guano from the walls. Bat guano […]
🧬 The Endothelium as a Viral Interface
John Murphy, CEO The COVID-19 Long-haul Foundation The endothelium, a monolayer of cells lining the interior of blood vessels, is often regarded as a passive conduit for blood flow. Yet […]
Hallucinations in COVID‑19: A Neurological and Clinical Synthesis
John Murphy, M.D., MPH, DPH President Covid-19 long-haul Foundation Coronavirus disease 2019 (COVID‑19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), emerged in late 2019 as a global respiratory […]
Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis […]