Endothelial cell damage is the central part of COVID-19 and a mouse model
induced by injection of the S1 subunit of the spike protein


Authors: Gerard J. NuovoCynthia MagroToni ShafferHamdy AwadDavid SusterSheridan MikhailBing HeJean-Jacques MichailleBenjamin LiechtyEsmerina Tili Annals of Diagnostic Pathology ABS T R A C TNeurologic complications of symptomatic COVID-19 are common. Brain tissues from 13 autopsies of people who died of COVID-19 were examined. Cultured endothelial and neuronal cells were incubated with and wild type mice were […]

Three years on, COVID-19 and the skin: long-term impacts, emerging trends and clinical practice 


Esther E Freeman, Ignacio Garcia-Doval, Luigi Naldi, Roderick J Hay British Journal of Dermatology, Volume 189, Issue 1, July 2023, Pages 1–, https://doi.org/10.1093/bjd/ljad131 In early 2020 there were reports of a new and potentially fatal viral infection affecting large numbers of people in Wuhan, China. Over the following 3 months it had spread throughout most of the world, with all countries […]

Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19


Carlos Garcia-Prieto, Eva Musulen, Veronica Davalos,  et. al.doi: https://doi.org/10.1101/2024.07.03.601404 00010010 Abstract Severe Coronavirus disease 2019 (COVID-19) induces heterogeneous and progressive diffuse alveolar damage (DAD) highly disrupting lung tissue architecture and homeostasis, hampering disease management and leading to fatal outcomes. Characterizing DAD pathophysiology across disease progression is of ultimate importance to better understand the molecular and cellular features driving different DAD patterns and […]

Research Suggests Unusual Form Of Cell Death Causes Severe COVID-19 Lung Damage


MAY 31, 2024 – Authored by Megan Redshaw, J.D. Epoch Times SARS-CoV-2 infection may cause severe pulmonary conditions such as pneumonia, inflammation, and acute respiratory distress syndrome, but until now, researchers have not understood the driving force behind lung damage caused by COVID-19. In a recently published paper in Nature Communications, researchers at Columbia University discovered […]

The Assessment of Functional Status Among COVID-19 Patients at Three Months Using Pulmonary Function Tests


Mohini Asija • Shaveta Dahiya • Rohit Parsad • Sanjay Fotedar • Rohit Sharma • Vikas Bhatthi  May 28, 2024, DOI: 10.7759/cureus.61221  Abstract Introduction The coronavirus disease 2019 (COVID-19) pandemic has impacted the lives of thousands of patients worldwide with many patients having residual symptoms months after the acute infection. The severity of lung involvement ranges from mild asymptomatic to severe acute respiratory distress syndrome (ARDS), […]

Emerging role of complement in COVID‑19 and other respiratory virus Diseases


Mark T. Xiao1 · Calder R. Ellsworth· Xuebin Qin,: 3 February 2024 Abstract The complement system, a key component of innate immunity, provides the first line of defense against bacterial infection; however, the COVID-19 pandemic has revealed that it may also engender severe complications in the context of viral respiratory disease. Here, we review the […]

Study points to vagus nerve dysfunction as a central pathophysiological feature of long COVID


by Emily Henderson, B.Sc.Feb 2022 News Medical Life Sciences New research to be presented at this year’s European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) suggests that many of the symptoms connected to post-COVID syndrome (PCC, also known as long COVID) could be linked to the effect of the virus on […]

COVID-19 Can Remain Undetected In Lungs For 18 Months: Study


DEC 14, 2023 – Authored by Amie Dahnke via The Epoch Times  The COVID-19 virus can remain in the lungs for months after an individual has been infected—even though it may be undetected by over-the-counter (OTC) tests, a new study finds. The findings, established by a research team from the Institut Pasteur in France and […]

New research points to possible reason for long COVID


A Spanish study suggests that SARS-CoV-2 mediated vagus nerve dysfunction (VND) could be responsible for long COVID. By SHIRA SILKOFF, FEBRUARY 2022 – The Jerusalem Post Many symptoms of post-COVID syndrome could be caused by lasting damage sustained to one of the most important nerves in the human body during initial infection with coronavirus, new research has […]

Many long-covid symptoms linger even after two years, new study shows


By Amy Goldstein, 2023, The Washington Post People who endured even mild cases of covid-19 are at heightened risk two years later for lung problems, fatigue, diabetes and certain other health problems typical of long covid, according to a new studythat casts fresh light on the virus’s true toll. The analysis, published Monday in the journal […]