Category: Spike Protein

Endothelial cell damage is the central part of COVID-19 and a mouse model
induced by injection of the S1 subunit of the spike protein

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Authors: Gerard J. NuovoCynthia MagroToni ShafferHamdy AwadDavid SusterSheridan MikhailBing HeJean-Jacques MichailleBenjamin LiechtyEsmerina Tili Annals of Diagnostic Pathology ABS T R A C TNeurologic complications of symptomatic COVID-19 are common. Brain tissues from 13 autopsies of people who died of COVID-19 were examined. Cultured endothelial and neuronal cells were incubated with and wild type mice were […]

UCSF Researchers Identify Major Driver Behind COVID And Long COVID, With Potential Treatment

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Authored by Marina Zhang via The Epoch Times Researchers at the University of California San Francisco have identified fibrin, a natural protein involved in blood clotting, as a major driver of the COVID-19 disease, according to a new study. Fibrin binds to proteins from the SARS-CoV-2 virus to form blood clots that are difficult to break down, the […]

Detection of recombinant Spike protein in the blood of individuals vaccinated against SARS-CoV-2: Possible molecular mechanisms

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Carlo Brogna, Simone Cristoni, et. al. 2023 Abstract Purpose The SARS-CoV-2 pandemic prompted the development and use of next-generation vaccines. Among these, mRNA-based vaccines consist of injectable solutions of mRNA encoding for a recombinant Spike, which is distinguishable from the wild-type protein due to specific amino acid variations introduced to maintain the protein in a prefused state. […]

Scientists ‘shocked’ and ‘alarmed’ at what’s in the mRNA shots

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Rebekah Barnett, 2023; Spectator Australia Early in 2023, genomics scientist Kevin McKernan made an accidental discovery. While running an experiment in his Boston lab, McKernan used some vials of mRNA Pfizer and Moderna Covid vaccines as controls. He was ‘shocked’ to find that they were allegedly contaminated with tiny fragments of plasmid DNA. McKernan, who […]

Billions Of Copies Of Residual DNA In A Single Dose Of COVID-19 mRNA Vaccine: Preprint

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NOV 2023 – Authored by Marina Zhang via The Epoch Times  A new preprint study up for peer review finds billions of residual DNA fragments in the COVID-19 mRNA vaccine vials. The lead author of the study, molecular virologist David Speicher, who has a doctorate in virology, told The Epoch Times that their study is “the […]

Therapeutic potential of convalescent plasma and hyperimmune immunoglobulins against SARS-CoV-2 BQ.1, BQ.1.1, and XBB variants

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Lorenza Bellusci, Hana Golding, and Surender Khurana Journal of Clinical Investigation Published 2023 – More infoView PDF  Convalescent plasma (CP) and hyperimmune intravenous immunoglobulins (IVIGs) are routinely used to treat patients with COVID-19. SARS-CoV-2 Omicron variants continue to evolve, generating multiple sublineages with increased transmissibility and antibody-escape mutations (1, 2). Several Omicron lineages that are currently circulating (BA.4, BA.5, […]

Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants

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Siriruk Changrob,1 Peter J. Halfmann,2 Hejun Liu,3 Jonathan L. Torres,3 Joshua J.C. McGrath,1 Gabriel Ozorowski,3 Lei Li,1 G. Dewey Wilbanks,1 Makoto Kuroda,2 Tadashi Maemura,2 Min Huang,1 Nai-Ying Zheng,1 Hannah L. Turner,3 Steven A. Erickson,4 Yanbin Fu,1 Atsuhiro Yasuhara,1 Gagandeep Singh,5,6 Brian Monahan,6,7 Jacob Mauldin,6,7 Komal Srivastava,6,7 Viviana Simon,5,6,7,8,9 Florian Krammer,5,6,7 D. Noah Sather,10,11,12 Andrew B. Ward,3 Ian A. Wilson,3,13 Yoshihiro Kawaoka,2,14,15,16 and Patrick C. Wilson1,Published 2023 – 10.1172/JCI166844 Abstract The rapid evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants […]

Does the SARS-CoV-2 spike really have an Achilles heel?

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Shiv Pillai, Published , 2023 – More infoView PDF , 10.1172/JCI168080 Abstract The continued emergence of SARS-CoV-2 variants and waning vaccine immunity are some of the factors that drive the continuing search for more effective treatment and prevention options for COVID-19. In this issue of the JCI, Changrob, et al. describe an anti-SARS-CoV-2 spike antibody, isolated from a […]

Rare Skin Reactions after mRNA Vaccination, Similar to Jones–Mote Basophil Responses

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Cutaneous Basophil Hypersensitivity Response after Skin-Test Antigen Injection. Philip W. Askenase, M.D., Yale University School of Medicine, New Haven, CT In a small group of recipients of messenger RNA (mRNA) vaccines against coronavirus disease 2019 (Covid-19), the occurrence of erythematous and indurated skin reactions has been reported at an average of 8 days after the […]

mRNA COVID Vaccines Form Spike Protein in Heart Cells, but Cause Different Anomalies: Research Article

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New research observing rat and human heart cells shows that within 48 hours of vaccination, the COVID-19 mRNA vaccines form spike proteins. By Marina Zhang,10/22/2023 New research out of Germany observing rat and human heart cells shows that within 48 hours of vaccination, the COVID-19 mRNA vaccines form spike proteins. Spike proteins, made from the mRNA […]