John Murphy, CEO The COVID-19 Long haul Foundation The mystery of COVID-19 may ultimately be less about the virus than about the person it encounters There is a peculiar cruelty […]
Renal Injury After COVID-19 Vaccination: Recommendations for Pathologists and Clinicians
John Murphy, CEO The COVID-19 Long haul Foundation Abstract The global deployment of SARS-CoV-2 vaccines has been accompanied by reports of acute kidney injury (AKI), glomerular disease, interstitial nephritis, podocytopathy […]
COVID-19 and the Kidney: From SARS-CoV-2 Infection and Acute Tubular Injury to Chronic Kidney Disease and Metabolic Dysfunction
John Murphy, CEO The COVID-19 Long haul Foundation Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a systemic disease in which renal involvement […]
Long COVID and Renal Disease: Pathophysiology, Genomics, Clinical Manifestations, and Long-Term Implications
Abstract Long coronavirus disease (Long COVID, post-acute sequelae of SARS-CoV-2 infection [PASC]) has emerged as a major chronic health challenge affecting multiple organ systems. Although pulmonary, cardiovascular, and neurologic manifestations […]
COVID-19–Associated Kidney Injury: Pathophysiology, Genomics, Clinical Progression, Therapeutic Strategies, and Long-Term Outcomes
A Comprehensive Scientific Review Abstract Since its emergence in 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been recognized not only as a respiratory pathogen but as a multisystem […]
COVID-19 and Edema
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has increasingly been recognized not merely as a viral pneumonic illness but as a diffuse endothelial and […]
Long COVID and the Kidney: Etiology, Genomic Susceptibility, Pathophysiology, and Clinical Management
John Murphy, M.D., M.P.H., D.P.H., President COVID-19 Long-haul Foundation A Comprehensive Review Table of Contents Abstract Introduction Figure 1: Schematic of systemic organ involvement in long COVID with emphasis on […]
COVID vaccine under new scrutiny after studies reveal possible health risks
Experts say studies don’t prove causation, but only show association By Melissa Rudy Fox News Two large studies have put a spotlight on potential health risks of the COVID vaccine — but some experts […]
Effect of positive end-expiratory pressure on acute kidney injury in patients with COVID-19
Poirot, Leo; Tchatat Wangueu, Lionel; Breteau, et. al. J Intensive Care BACKGROUND: Acute Kidney Injury (AKI) is common in patients admitted to the intensive care unit (ICU) for severe SARS-CoV-2 […]
Kidney disorders as serious adverse drug reactions of remdesivir in coronavirus disease
Laurent Chouchana 1,∗, Laure-Hélène Preta 1, Mylène Tisseyre 1, et. al., PMCID: PMC7907730 PMID: 33647327 Remdesivir is a novel adenosine-like nucleotide analogue, representing the first drug approved for coronavirus disease 2019 (COVID-19), albeit an uncertain clinical relevance. In […]