John Murphy, CEO, The COVID-19 Long haul Foundation A mechanistic synthesis of post-acute neurological sequelae of SARS-CoV-2 infection Abstract Neurological manifestations constitute one of the most consequential and biologically heterogeneous […]
Long COVID as a Spectrum of Distinct Biological Phenotypes
A mechanistic synthesis of the emerging phenotype-based model of post-acute sequelae of SARS-CoV-2 infection John Murphy, CEO The COVID-19 Long haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 […]
Long COVID Is Real. The Mystery Is Why It Takes So Many Forms?
Six years after SARS-CoV-2 emerged, researchers are no longer asking whether patients are sick. They are trying to understand why the same infection can leave one person with debilitating fatigue, […]
Autonomic Dysfunction as a Major Phenotype of Long COVID
Etiology, pathology, genomics, physiology, and clinical course of post-SARS-CoV-2 autonomic disease John Murphy, CEO, The COVID-19 Long haul Foundation Abstract Autonomic dysfunction has emerged as one of the most reproducible […]
Mitochondrial and Metabolic Dysfunction in Long COVID: A Bioenergetic Model of Fatigue, Post-Exertional Malaise, and Multisystem Disease
Etiology, pathology, genomics, physiology, and clinical course Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a heterogeneous multisystem disorder in which fatigue, post-exertional malaise, cognitive dysfunction, autonomic […]
Long COVID Patients Have 18% Fewer Dopamine Nerve Endings, Brain Scans Reveal
Felicity Nelson COVID-19 can cause brain injuries that are still visible on scans years later in people with neurological symptoms related to long COVID. Existing research shows that cognitive dysfunction in […]
Long Covid and Depression: Neuroinflammation, Systemic Illness, and the Persistence of Affective Dysfunction
John Murphy, CEO, The COVID-19 Long-haul Foundation Review Article Abstract Long Covid, or post–COVID-19 condition, has emerged as a heterogeneous, multisystem disorder that may persist for months or years after […]
Long COVID and Peripheral Neuropathy: Clinical Phenotypes, Pathobiology, Diagnosis, and Treatment
John Murphy, CEO, The Covid-19 Long Haul Foundation A Narrative Review Abstract Importance: Peripheral nervous system dysfunction is increasingly recognized among the neurological manifestations of Long COVID. Small-fiber neuropathy (SFN), […]
Multidisciplinary Care Pathways for Long COVID Fatigue:
A Systems-Based Model Integrating Rehabilitation Medicine, Neuroimmunology, Autonomic Care, and Precision Phenotyping Abstract Background Long COVID, also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one […]
Long COVID and Persistent Pulmonary Dysfunction: Emerging Evidence for Chronic Respiratory Sequelae, Pulmonary Pathology, and Dyspnea
John Murphy, President COVID-19 Long-haul Foundation Abstract Long COVID, also termed post-COVID condition or post-acute sequelae of SARS-CoV-2 infection (PASC), continues to represent one of the most consequential chronic disease […]