COVID-19 has been followed by reports of narcolepsy, overwhelming daytime sleepiness and episodes of lost consciousness. Some patients have crashed cars or been injured. Vaccination has also been followed by […]
When COVID Takes Your Balance
Falls among older Americans were already a public-health crisis. Then came a virus capable of disturbing oxygenation, blood pressure, cognition, muscle function and balance — and a vaccination campaign in […]
Why Does COVID-19 Devastate Some People and Barely Touch Others?
John Murphy, CEO The COVID-19 Long haul Foundation The mystery of COVID-19 may ultimately be less about the virus than about the person it encounters There is a peculiar cruelty […]
SARS-CoV-2, Mesenteric Vascular Injury and Ischemic Enterocolitis
John Murphy, CEO The COVID-19 Long haul Foundation Abstract SARS-CoV-2 infection can produce clinically important gastrointestinal vascular injury, including acute mesenteric ischaemia, mesenteric arterial and venous thrombosis, non-occlusive mesenteric ischaemia, […]
The COVID Sleep Crisis
For millions of people, COVID didn’t just steal their energy. It changed the way they sleep. By John Murphy, CEO The COVID Long haul Foundation At 3 a.m., the house […]
When the Lights Go Out: Long COVID, Transient Loss of Consciousness, Sleep Disturbance, and the Unfinished Science of Cerebral Autonomic Dysfunction
John Murphy, CEO The COVID-19 Long haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has increasingly been recognized as a multisystem disorder in which neurological, cardiovascular, […]
The Neurological Sequelae of COVID-19: Long-Term Injury to the Central Nervous System, Neuroimaging, Neuropathology, and Emerging Mechanisms of Long COVID
John Murphy, CEO The COVID-19 Long-haul Foundation Introduction The neurological consequences of SARS-CoV-2 infection have evolved from an initially unexpected collection of clinical observations into a substantial body of neuropathological, […]
COVID Mortality and Mechanical Ventilation: What the U.S. Clinical Evidence Actually Shows
John Murphy, CEO The COVID-19 Long haul Foundation Executive finding The available evidence supports three conclusions simultaneously: There is, however, strong evidence that hospital mortality fell dramatically during 2020 even […]
Neurological Long COVID
John Murphy, CEO, The COVID-19 Long haul Foundation A mechanistic synthesis of post-acute neurological sequelae of SARS-CoV-2 infection Abstract Neurological manifestations constitute one of the most consequential and biologically heterogeneous […]
Long COVID as a Spectrum of Distinct Biological Phenotypes
A mechanistic synthesis of the emerging phenotype-based model of post-acute sequelae of SARS-CoV-2 infection John Murphy, CEO The COVID-19 Long haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 […]