Category: Pathology

Outcome of Glomerular Disease Manifesting After Vaccination Against Severe Acute Respiratory Syndrome Coronavirus 2

Posted on | Posted on John Murphy | Leave a Comment on Outcome of Glomerular Disease Manifesting After Vaccination Against Severe Acute Respiratory Syndrome Coronavirus 2

Shuvam Roy • Anupma Kaul • Monika Yachha • et. al. Published: July 03, 2024, DOI: 10.7759/cureus.63767  Abstract Introduction Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can upregulate the immune system and may contribute to glomerular disease (GD). Here, we describe a spectrum of GD that manifested following vaccination against SARS-CoV-2 (COVID-19 vaccinations). Material and methods This was a descriptive study […]

Pathophysiological, immunological, and inflammatory features of long COVID

Posted on | Posted on John Murphy | Leave a Comment on Pathophysiological, immunological, and inflammatory features of long COVID

Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1 , et. al., Front. Immunol., 27 February 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have […]

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Sydney R. Stein, Sabrina C. Ramelli, Alison Grazioli, Joon-Yong Chung, Manmeet Singh, Claude Kwe Yinda, Clayton W. Winkler, Junfeng Sun, James M. Dickey, Kris Ylaya, Sung Hee Ko, et. al. Nature volume 612, pages758–763 (2022)Cite this article Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1,2,3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 […]

Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

Posted on | Posted on John Murphy | Leave a Comment on Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

Janessa Y.J. Tan,1 Danielle E. Anderson,2,3 Abhay P.S. Rathore,4 Aled O’Neill,1 Chinmay Kumar Mantri,1 Wilfried A.A. Saron,1 Cheryl Q.E. Lee,5 Chu Wern Cui,5 Adrian E.Z. Kang,1 Randy Foo,1 Shirin Kalimuddin,1,6 Jenny G. Low,1,6 Lena Ho,5 Paul Tambyah,7,8 Thomas W. Burke,9 Christopher W. Woods,9,10 Kuan Rong Chan,1 Jörn Karhausen,4,11 and Ashley L. St. John1,4,12,13 Published August 10, 2023 – 10.1172/JCI149834 Journal of Clinical Investigation Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients […]

Spectrum of Fibrotic Lung Diseases

Posted on | Posted on John Murphy | Leave a Comment on Spectrum of Fibrotic Lung Diseases

Marlies Wijsenbeek, M.D., and Vincent Cottin, M.D.  New England Journal of Medicine 2023 Diffuse parenchymal lung diseases encompass a large number of conditions, with a wide range of causes, clinical manifestations, and imaging and pathological features, as well as variable outcomes. Despite the intrinsic heterogeneity of this group of diseases, in most of them, the […]

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Authors: by Covid Strategies | Dec 14, 2022 | Science & News Nature Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1,2,3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 (refs. 4,5). However, the burden of infection outside the respiratory tract and time to viral clearance […]

COVID-19 Autopsies Uncover Ways The Coronavirus Kills April 29, 2021 Angus Chen

Posted on | Posted on John Murphy | Leave a Comment on COVID-19 Autopsies Uncover Ways The Coronavirus Kills April 29, 2021 Angus Chen

When patients become severely ill with COVID-19, the coronavirus infiltrates deep into the lungs and causes mayhem on the tissues that line the organ. The infection can cause swelling, and fluid and debris can start to fill the lungs. It can feel like drowning on dry land. Patients who remember being intubated sometimes describe the […]

Pathophysiology and Management of Tongue Involvement in COVID-19 Patients

Posted on | Posted on John Murphy | Leave a Comment on Pathophysiology and Management of Tongue Involvement in COVID-19 Patients

Authors: Zeinab Mohseni Afshar, Mohammad Barary, Soheil Ebrahimpour, Alireza Janbakhsh, Mandana Afsharian, Amirhossein Hasanpour & Arefeh Babazadeh Indian Journal of Otolaryngology and Head & Neck Surgery (2022) Abstract Evaluate the lingual manifestations of COVID-19, and provide a clinical guide in managing these symptoms. Electronic databases, such as PubMed/Medline, and Scopus were searched until November 1, 2020, and only randomized controlled trials, cross-sectional and cohort […]

‘Never Seen’ Before: Embalmers Finding Long, Rubbery Clots Inside Corpses Since Implementation of Covid Vaccines

Posted on | Posted on John Murphy | Leave a Comment on ‘Never Seen’ Before: Embalmers Finding Long, Rubbery Clots Inside Corpses Since Implementation of Covid Vaccines

By Cristina Laila September 4, 2022 Embalmers are finding long, rubbery clots inside of corpses since the implementation of Covid vaccines. According to one Alabama embalmer who has been treating corpses for over 20 year, the strange fibrous clots emerged in May of 2021, shortly after the Covid vaccines first became available to the public. “It […]

Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

Posted on | Posted on John Murphy | Leave a Comment on Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

Authors: Ibolya Rutkai, Meredith G. Mayer, Linh M. Hellmers, Bo Ning, Zhen Huang, Christopher J. Monjure, Carol Coyne, Rachel Silvestri, Nadia Golden, Krystle Hensley, Kristin Chandler, Gabrielle Lehmicke, Gregory J. Bix, Nicholas J. Maness, Kasi Russell-Lodrigue, Tony Y. Hu, Chad J. Roy, Robert V. Blair, Rudolf Bohm, Lara A. Doyle-Meyers, Jay Rappaport & Tracy Fischer  Nature Communications volume 13, Article number: 1745 (2022)  Published: 01 April 2022 Abstract Neurological manifestations are a significant complication of coronavirus disease (COVID-19), but underlying mechanisms aren’t well […]