The COVID-19 Long Haul Foundation

Treatment, Referral & Educational Support for COVID-19 Illnesses & Vaccine Injury

Cardiovascular / Fatigue / Gastrointestinal / Inflammation / Metabolic Dysregulation / Neurocognitive / Neuropathy / Phenotype / Postural Orthostatic Tachycardia (POTS) / Respiratory Syndrome / Vascular System Posted on:

Long COVID as a Spectrum of Distinct Biological Phenotypes

A mechanistic synthesis of the emerging phenotype-based model of post-acute sequelae of SARS-CoV-2 infection John Murphy, CEO The COVID-19 Long haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 […]

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Acute transverse myelitis / Axonal Injury / Blood brain barrier / Concerns / Cytokine Storm / Encephalomyelitis / Encephalopathy / Epidemiology / Gray matter / Guillain Barre / Guillian-Barre Syndrome / Inflammation / Ischemic Stroke / Neurologic Effects / Neuromyelitis optica / Oligodendrocyte injury / Oxidative stress / Transverse Myelitis / Vaccine Enhanced Disease / Vaccine News / Vaccine Safety / White matter Posted on:

Transverse myelitis:Genomics, Cell Biology, Clinical Manifestations, Diagnosis, Treatment, and Long-Term Prognosis

Author: John Murphy, CEO, The COVID-19 Long Haul Foundation Abstract Background Transverse myelitis (TM) is an uncommon inflammatory disorder of the spinal cord characterized by acute or subacute neurological dysfunction […]

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Dysautonomia / Epidermis / Epithelium / Immune dysregulation / Inflammation / Itch / Itching / Mast Cell / Mast cell activation syndrome / Skin-Dermatology Posted on:

Long COVID, Chronic Urticarial Pruritus

Background John Murphy, CEO COV-19 Long-haul Foundation Persistent dermatologic manifestations represent an increasingly recognized component of post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID. Among these manifestations, chronic […]

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Anxiety / Circadian Rhythm / Cognitive deficit / Depression & Mental Health / Fatigue / Inflammation / Mitochondria / Neurologic Effects / PASC / Sleep & Dreams / Sleep Deprivation / Sleep Disturbance Posted on:

Long COVID and Sleep Disorders: An Emerging Biologic Nexus in Post-Acute Sequelae of SARS-CoV-2 Infection

John Murphy, CEO, COVID-19 Long-haul Foundation Abstract Sleep disturbance has emerged as one of the most prevalent, persistent, and disabling manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), commonly known […]

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Clots & Bleeds / Endothelium / Hyperinflammation / Inflammasome / Inflammation / ME/CFS / Nitric oxide Posted on:

Long COVID and Vascular Injury in 2026: Emerging Evidence for Endothelial Dysfunction, Microvascular Disease, and Persistent Immunothrombotic Pathology

John Murphy, M.D., M.P.H., D.P.H. President COVID-19 Long-haul Foundation Abstract Long COVID, also termed post-COVID condition or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one of the most […]

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Dysautonomia / Endothelium / Immune System / Inflammation / Mitochondria / Mitochondrial dysfunction / Mitochondrial Effects / Treatments Posted on:

Treatment Landscape in Long COVID Has Expanded Beyond “Supportive Care”

A Mechanism-Driven Reframing of Therapeutic Development in Post–Acute SARS-CoV-2 Disease John Murphy, M.D, M.P.H., D.P.H. President COVID Long-haul Foundation Conceptual Shift and Therapeutic Reclassification ABSTRACT For much of the early […]

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Autonomic nervous system disruption / Brain / Cognitive deficit / Cytokine Storm / Endothelium / Fatigue / Hyperinflammation / Inflammasome / Inflammation / Inflammation / Microvascular damage / Mitochondria / Mitochondrial dysfunction / Mitochondrial Effects / Neuropathy Posted on:

Persistent Viral Reservoirs and Immune Dysregulation in Long COVID

John Murphy, M.D., M.P.H., D.P.H., President Covid-19 Long-haul Foundation The Central Discovery Reshaping Post-Acute Sequelae Research Abstract Long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC) has emerged as a multisystem […]

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