Inhibiting a protein associated with chronic inflammation improves lung health in mice with COVID-19. Helena Kudiabor, Nature A signalling molecule that helps to kick-start inflammation in the lungs could play a key part in aggravating some long COVID symptoms, finds a study that analysed lung samples from people with the condition. The findings, published in Science Translational Medicine on […]
Pin Fee Chong, , Kanako Higashi, Wakato Matsuoka, et. al.BMC Neurology volume 24, Article number: 17 (2024) Abstract Background The systemic manifestations of coronavirus disease 2019 (COVID-19) include hyperinflammatory reactions in various organs. Recent studies showed evidence for the frequent involvement of central nervous system in affected patients; however, little is known about clinical features of cerebrovascular diseases in childhood-onset COVID-19. Case presentation […]
BMJ 2024; 385 doi: https://doi.org/10.1136/bmj.q897 (Published 15 May 2024)Cite this as: BMJ 2024;385:q897 What are the neurological symptoms of covid-19? Covid may be primarily a respiratory infection, but a common symptom is “brain fog”—problems with memory or concentration—which can persist for weeks or months as part of long covid.1 And it’s not the only neurological effect. Giovanni Schifitto, professor of neurology at the […]
2024, By DAVID NIELD, Science Alert Some form of brain injury could be behind the symptoms reported by those with long COVID, according to a new study, and adapting tests and treatments to match could aid progress in tackling the condition. Analyzing 203 patients hospitalized with COVID-19 or its associated symptoms, and comparing the results with 60 people […]
Stefania Campana; Claudia De Pasquale; Giacomo Sidoti Migliore;, et. al. J Immunol (2022) 209 (4): 655–659. https://doi.org/10.4049/jimmunol.2200021 Abstract Proinflammatory monocytes play a preponderant role in the development of a cytokine storm causing fatal consequences in coronavirus disease 2019 (COVID-19) patients, highlighting the importance of analyzing in more detail monocyte distribution in these patients. In this study, […]
By University of Colorado at Boulder, University of Colorado Boulder scientists have discovered that proteins left by COVID-19 can significantly lower cortisol levels in the brain, leading to heightened immune responses to new stressors. This research, focusing on the neurological symptoms of Long COVID, utilized rats to demonstrate how SARS-CoV-2 antigens persist in the body and alter brain function. This […]
Shreya Ghimire, Biyun Xue, Kun Li, Ryan M Gannon, et. al.doi: https://doi.org/10.1101/2024.07.03.60194 Abstract Treatments available to prevent progression of virus-induced lung diseases, including coronavirus disease 2019 (COVID-19) are of limited benefit once respiratory failure occurs. The efficacy of approved and emerging cytokine signaling-modulating antibodies is variable and is affected by disease course and patient-specific inflammation patterns. Therefore, understanding the role of inflammation on the […]
Authors: Christian Baumeier 1, Ganna Aleshcheva 1, Dominik Harms 1, et. al. Int J Mol Sci 2022 Jun 22;23(13):6940. doi: 10.3390/ijms23136940. Abstract Myocarditis in response to COVID-19 vaccination has been reported since early 2021. In particular, young male individuals have been identified to exhibit an increased risk of myocardial inflammation following the administration of mRNA-based vaccines. Even though the first epidemiological analyses […]
Aparna P. Patange • Jabbar V. Desai • Bhupal Pujari • Aparna Marwah • Animesh Dey, Published: July 01, 2024, DOI: 10.7759/cureus.63593 Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to substantial morbidity and mortality worldwide. Hematological abnormalities are common in COVID-19 patients and play a significant role in disease pathogenesis and prognosis. Objective: […]
Saurabh Mehandru & Miriam Merad, Nature Immunology volume 23, pages194–202 ( Abstract The world continues to contend with successive waves of coronavirus disease 2019 (COVID-19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and often debilitating sequelae are increasingly recognized in convalescent individuals, named ‘post-COVID-19 syndrome’ or ‘long-haul COVID’. Clinical symptomatology includes fatigue, malaise, dyspnea, defects […]