Category: Inflammation

Efficacy and Safety of Lithium Treatment in SARS-CoV-2 Infected Patients

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Carlos Spuch, 1 ,* † Marta López-García, 1 , 2 , † Tania Rivera-Baltanás, 1 ,  , et.al. Front Pharmacol. 2022; 13: 850583. Published online 2022 Apr 14. doi:  10.3389/fphar.2022.850583PMCID: PMC9046673PMID: 35496309 Abstract At the beginning of the pandemic, we observed that lithium carbonate had a positive effect on the recovery of severely ill patients with COVID-19. Lithium is able to inhibit the replication of several types of […]

Long COVID: Is there a kidney link?

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Raymond E. Garrett, Carlos H. Palacio, David Bar-Or: HYPOTHESIS AND THEORY article, Front. Med., 03 April 2023, Sec. Nephrology, Volume 10 – 2023 | https://doi.org/10.3389/fmed.2023.1138644 Metabolic causes such as altered bioenergetics and amino acid metabolism may play a major role in Long COVID. Renal-metabolic regulation is an integral part of these pathways but has not been […]

FDA System Unable To Identify Risk Of Heart Inflammation After COVID-19 Vaccination: Agency

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DEC 10, 2023 – Authored by Zachary Stieber via The Epoch Times  The U.S. Food and Drug Administration could not provide information on a confirmed side effect of the Pfizer COVID-19 vaccine, according to a newly disclosed document. FDA staffers said in the document, from 2021, that one of the agency’s top surveillance systems was unable […]

The Long-term Cardiovascular Impact of COVID-19

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Coronavirus (COVID-19) | January 22, 2021 | Dave Fornell, Editor DAIC Evidence suggests COVID long-haulers may have lingering cardiac impacts from their coronavirus infections Cardiologists are taking a closer look at the possible long-term cardiovascular effects on COVID long-hauler patients who still show symptoms long after they should be recovered from the virus. Getty Images “So this […]

Cardiorespiratory dysautonomia in post-COVID-19 condition: Manifestations, mechanisms and management

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Artur Fedorowski, Monika Fagevik Olsén, Frida Nikesjö, Christer Janson, Judith Bruchfeld, Maria Lerm, Kristofer Hedma: May 2023, Journal of Internal MedicineVolume 294, Issue 5 p. 548-562 Abstract A significant proportion of COVID-19 patients experience debilitating symptoms for months after the acute infection. According to recent estimates, approximately 1 out of 10 COVID-19 convalescents reports persistent health issues more than 3 months after […]

What Happens When You Still Have Long COVID Symptoms?

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BY KATHY KATELLA OCTOBER 27, 2023, Yale Medicine Yale’s Long COVID program aims to treat patients with lingering COVID-19 symptoms, such as fatigue, brain fog, and shortness of breath. Note: Information in this article was accurate at the time of original publication. Because information about COVID-19 changes rapidly, we encourage you to visit the websites of the […]

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

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Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, et. al. Nature volume 604, pages697–707 (2022)Cite this article Abstract There is strong evidence of brain-related abnormalities in COVID-191,2,3,4,5,6,7,8,9,10,11,12,13. However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here we investigated brain changes in 785 […]

Long COVID: Antibodies in cerebrospinal fluid linked with brain fog

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Deep Shukla, 2022 Medical News Today Coronavirus data Brain fog, or cognitive dysfunction, is one of the most common symptoms that health professionals observe in individuals with long COVID, or post-acute COVID-19. A recent study by researchers at the University of California, San Francisco (UCSF) suggests a link between the presence of persistent cognitive symptoms several months after a SARS-CoV-2 […]

C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps

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Bruna M. Silva,1,2 Giovanni F. Gomes,1 Flavio P. Veras,1 Seppe Cambier,3 Gabriel V.L. Silva,1,2 Andreza U. Quadros,1 Diego B. Caetité,1,2 Daniele C. Nascimento,1,2 Camilla M. Silva,1,2 Juliana C. Silva,1 Samara Damasceno,1 Ayda H. Schneider,1 Fabio Beretta,3 Sabrina S. Batah,4 Icaro M.S. Castro,5 Isadora M. Paiva,1 Tamara Rodrigues,1,2 Ana Salina,1,6 Ronaldo Martins,6,7 Guilherme C.M. Cebinelli,1,2 Naira L. Bibo,1 Daniel M. Jorge,6,7 Helder I. Nakaya,5 Dario S. Zamboni,1,6 Luiz O. Leiria,1,2 Alexandre T. Fabro,4 José C. Alves-Filho,1,2 Eurico Arruda,6,7 Paulo Louzada-Junior,1,8 Renê D. Oliveira,1,8 Larissa D. Cunha,1,6 Pierre […]

Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19

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Janessa Y.J. Tan,1 Danielle E. Anderson,2,3 Abhay P.S. Rathore,4 Aled O’Neill,1 Chinmay Kumar Mantri,1 Wilfried A.A. Saron,1 Cheryl Q.E. Lee,5 Chu Wern Cui,5 Adrian E.Z. Kang,1 Randy Foo,1 Shirin Kalimuddin,1,6 Jenny G. Low,1,6 Lena Ho,5 Paul Tambyah,7,8 Thomas W. Burke,9 Christopher W. Woods,9,10 Kuan Rong Chan,1 Jörn Karhausen,4,11 and Ashley L. St. John1,4,12,13 Published August 10, 2023 – 10.1172/JCI149834 Journal of Clinical Investigation Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients […]