Category: Thrombosis

SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation

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Authors: Luca Perico 1, Marina Morigi 1, et. al.; 2022 Mar 7;13:827146. doi: 10.3389/fimmu. 2022.827146. eCollection 2022. Abstract Microvascular thrombosis is associated with multiorgan failure and mortality in coronavirus disease 2019 (COVID-19). Although thrombotic complications may be ascribed to the ability of SARS-CoV-2 to infect and replicate in endothelial cells, it has been poorly investigated whether, in the complexity of viral […]

Doxycycline’s Potential Role in Reducing Thrombosis and Mortality in Critically Ill Patients With COVID-19: A Multicenter Cohort Study

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Khalid Al Sulaiman, MBA, BCCCP, BCNSP, FCCM https://orcid.org/0000-0002-5547-2043,  Ohoud Aljuhani, PharmD, […], and Ghassan Alghamdi, MD Abstract Doxycycline has revealed potential effects in animal studies to prevent thrombosis and reduce mortality. However, less is known about its antithrombotic role in patients with COVID-19. Our study aimed to evaluate doxycycline’s impact on clinical outcomes in critically ill patients with COVID-19. A multicenter retrospective cohort study […]

Diagnosis of venous thromboembolic diseases in people with covid-19: summary of updated NICE guidance

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BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2204 (Published 12 October 2023)Cite this as: BMJ 2023;383:p2204, Sarah Boyce, senior technical analyst1,  Emma McFarlane, Susan Harrison, Terry McCormack What you need to know In venous thromboembolism, a blood clot usually forms in the deep veins of the legs or pelvis. This is known as deep vein thrombosis, and the blood clot can dislodge from these sites, […]

Vaccine-induced immune thrombotic thrombocytopenia

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BLOOD SPOTLIGHT| APRIL 6, 2023 Douglas B. Cines, Andreas Greinacher Blood (2023) 141 (14): 1659–1665. https://doi.org/10.1182/blood.2022017696 Within the first months of the COVID-19 vaccination campaign, previously healthy recipients who developed severe thrombosis (often cerebral and/or splanchnic vasculature) and thrombocytopenia typically after adenoviral vector-based vaccination were identified. Similarities between this syndrome, vaccine-induced immune thrombotic thrombocytopenia (VITT), and heparin-induced […]

Brain Injuries After COVID Vaccination

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HEALTH VIEWPOINTS Colleen Huber    April 12, 2023 There are back door routes to the brain. COVID vaccine developers have traversed a path through those doors. And they knew they had entered the brain by November 2020, before the vaccine rollout. We have 86 billion neurons in the human brain, and each of those connects with […]

Covid linked to 33-fold increase in risk of potentially fatal blood clot

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Infection with virus also associated with fivefold increase in risk of deep vein thrombosis, data suggests Authors: Linda Geddes The Guardian Catching Covid is associated with a fivefold increase in the risk of deep vein thrombosis (DVT) and a 33-fold increase in risk of a potentially fatal blood clot on the lung in the 30 […]

Ocular Adverse Events After COVID-19 Vaccination

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Authors: Xin Le Ng, MBBS, a Bjorn Kaijun Betzler, MBBS, b Ilaria Testi, MD, c Su Ling Ho, FRCS, a Melissa Tien, FRCOphth, a Wei Kiong Ngo, FRCOphth, a Manfred Zierhut, PhD, d Soon Phaik Chee, FRCSEd, e , f , g Vishali Gupta, PhD, h Carlos E Pavesio, FRCOphth, b Marc D. de Smet, PhD, i , j and Rupesh Agrawal, FRCS a , b , e , f , g , k Ocul Immunol Inflamm. 2021 : 1–9. Published online 2021 Sep 24. doi: 10.1080/09273948.2021.1976221 PMCID: PMC8477588 PMID: 34559576 ABSTRACT […]

Growing Number Of COVID-19 Deaths Among Vaccinated People: Federal Data

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Authors: Katabella Roberts via The Epoch Times MY 13, 2022 An increasing number of COVID-19 deaths are occurring among individuals in the United States who have been vaccinated, according to federal data. In August of 2021, roughly 18.9 percent of COVID-19 deaths happened among individuals who were vaccinated, an ABC News analysis of the data shows. Six months later in February 2022, […]

Acute Mesenteric Ischemia in COVID-19 Patients

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Authors: Dragos Serban 1,2,*† , Laura Carina Tribus 3,4,†, Geta Vancea 1,5,† , Anca Pantea Stoian, Ana Maria Dascalu 1,* Andra Iulia Suceveanu 6Ciprian Tanasescu 7,8, Andreea Cristina Costea 9 Mihail Silviu Tudosie 1, Corneliu Tudor 2, Gabriel Andrei Gangura 1,10, Lucian Duta 2 and Daniel Ovidiu Costea 6,11, Abstract: Acute mesenteric ischemia is a […]

Intestinal Damage in COVID-19: SARS-CoV-2 Infection and Intestinal Thrombosis

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Authors: Xiaoming Wu1, Haijiao Jing1, Chengyue Wang1, Yufeng Wang1, Nan Zuo1, Tao Jiang2*, Valerie A. Novakovic3 and Jialan Shi1,3,4* Front. Microbiol., 22 March 2022 | https://doi.org/10.3389/fmicb.2022.860931 The intestinal tract, with high expression of angiotensin-converting enzyme 2 (ACE2), is a major site of extrapulmonary infection in COVID-19. During pulmonary infection, the virus enters the bloodstream forming viremia, which infects and damages extrapulmonary organs. Uncontrolled viral […]