The COVID-19 Long Haul Foundation

Treatment, Referral & Educational Support for COVID-19 Illnesses & Vaccine Injury

Autonomic nerves / Autonomic nervous system disruption / Central autonomic network / CNS / Dysautonomia / Endothelium / Etiology / Gastrointestinal / Immune Modulators / Immune System / Immunopathology / Mitochondrial depletion / Orthostatic intolerance / Outcomes / Pathology / Pathophysiology / Postural Orthostatic Tachycardia (POTS) / Sleep Disturbance / Tachycardia / Temperature / Treatments / Vagus Nerve Posted on:

Long COVID and Dysautonomia: Emerging Insights Into Autonomic Dysfunction, Vagal Pathobiology, Neuroimmune Interactions, and Therapeutic Strategies

John Murphy, M.D., M.P.H., D.P.H. CEO COVID Long-haul Foundation Abstract Background Long COVID, also termed Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), is a complex multisystem disorder characterized by persistent symptoms […]

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Brain Fog / Endothelium / Exercise Intolerance / Fatigue / Immune System / Long COV / Long-haul Disease / Mitochondria / Mitochondrial dysfunction / Palpitations / PASC / Post-infectious Syndrome / T-cell Posted on:

Recognition of Long COVID as a Heterogeneous Post-Infectious Syndrome

Toward a Multisystem Endotype Framework for Post–Acute SARS-CoV-2 Disease John Murphy, M.D., M.P.H., D.P.H. President Covid-19 Long-haul Foundation Abstract Long COVID (post–acute sequelae of SARS-CoV-2 infection, PASC) has emerged as […]

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Dysautonomia / Endothelium / Immune System / Inflammation / Mitochondria / Mitochondrial dysfunction / Mitochondrial Effects / Treatments Posted on:

Treatment Landscape in Long COVID Has Expanded Beyond “Supportive Care”

A Mechanism-Driven Reframing of Therapeutic Development in Post–Acute SARS-CoV-2 Disease John Murphy, M.D, M.P.H., D.P.H. President COVID Long-haul Foundation Conceptual Shift and Therapeutic Reclassification ABSTRACT For much of the early […]

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B-cell / CD4 / CD8 / Lymphadenopathy / Lymphocyte / T-cell Posted on:

Persistent attenuation of lymphocyte subsets after mass SARS-CoV-2 infection

Zhengqi Jiang ∙ Tichao Shan∙ Yucan Li ∙ Heyu Ni ∙ et. al., DOI: 10.1016/j.ijid.2025.108287 External Link Also available on ScienceDirect External Link Highlights SARS-CoV-2 causes lasting immune dysregulation for over 20 months. The impact of SARS-CoV-2 on lymphocytes was especially severe in patients […]

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