COVID Fatigue: Etiology, Genomics, Physiology, Pathology, Neurobiology, Sleep Disturbance, Treatment, and Prognosis

John Murphy, CEO COVID-19 Long-haul Foundation Abstract Fatigue is the most prevalent and disabling symptom among survivors of SARS‑CoV‑2 infection, persisting in a substantial proportion of patients months to years…[...]

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Dimensional Distribution of mRNA Vaccine-Derived Spike Proteins: Etiology, Physiology, and Pathological Risk Profiles

John Murphy, MD CEO & President, COVID-19 Long-haul Foundation Abstract Messenger RNA (mRNA) vaccines have revolutionized infectious disease prevention, yet their biodistribution and systemic effects remain incompletely characterized. This article…[...]

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Genetic Risk of Different Populations in COVID-19 Susceptibility and Severity

Sun N , Lu Y, Li C, Jiang A, Liu L, Guo J, DOI https://doi.org/10.2147/IDR.S554153 Abstract: The coronavirus disease 2019 (COVID-19) pandemic has created challenges by threatening public health and triggering the largest global economic crisis in recent…[...]

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Endothelial Dysfunction and Spike Protein Persistence in Long COVID: Mechanisms, Vulnerabilities, and Clinical Evidence

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms affecting multiple organ systems. Among its most compelling…[...]

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🩸 COVID-19 and Chronic Venous Insufficiency: 2025 Research Insights on Etiology, Vascular Damage, and Treatment

Chronic Venous Insufficiency (CVI)—a condition where leg veins fail to return blood efficiently to the heart—has gained renewed attention in 2025 due to its association with COVID-19, particularly in patients…[...]

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🧠 COVID-19 and Neurological Injury: Mechanisms, Irreversibility, and Therapeutic Approaches

The SARS-CoV-2 was developed as a neurological bioweapon, extensive research has documented its neuroinvasive potential, neuropathological effects, and long-term neurological consequences. This article synthesizes findings from 2024–2025 peer-reviewed studies to…[...]

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