Authors: Larissa E van Eijk, 1 , † Mathijs Binkhorst, 2 , † Arno R Bourgonje, 3 , ‡ Annette K Offringa, 4 , ‡ Douwe J Mulder, 5 Eelke M Bos, 6 Nikola Kolundzic, 7 , 8 Amaal E Abdulle, 5 Peter HJ van der Voort, 9 Marcel GM Olde Rikkert, 10 Johannes G […]
Can COVID-19 Immunity Last for Years?
Author: Christina Aungst, PharmD Key takeaways: People who were sick with COVID-19 and recovered might have long-term immunity that lasts for months or years. We don’t know how long vaccine […]
SARS-CoV-2-Specific Memory T Lymphocytes From COVID-19 Convalescent Donors: Identification, Biobanking, and Large-Scale Production for Adoptive Cell Therapy
Syndrome coronavirus 2 (SARS-CoV-2) pandemic is causing a second outbreak significantly delaying the hope for the virus’ complete eradication. In the absence of effective vaccines, we need effective treatments with […]
What is the role of T cells in COVID-19 infection? Why immunity is about more than antibodies
Summary CD4+ T cells help B cells to produce antibodies and help CD8+ T cells to kill virus-infected cells One of the dominant cytokines produced by T cells is interferon […]
T cell responses in patients with COVID-19
The role of T cells in the resolution or exacerbation of COVID-19, as well as their potential to provide long-term protection from reinfection with SARS-CoV-2, remains debated. Nevertheless, recent studies […]
Understanding How COVID-19 Vaccines Work
How COVID-19 Vaccines Work COVID-19 vaccines help our bodies develop immunity to the virus that causes COVID-19 without us having to get the illness. Different types of vaccines work in […]
Immune T Cells May Offer Lasting Protection Against COVID-19
Much of the study on the immune response to SARS-CoV-2, the novel coronavirus that causes COVID-19, has focused on the production of antibodies. But, in fact, immune cells known as memory […]
COVID-19 Attacks Endothelial Cells
The pandemic virus SARS-CoV-2 can enter the body via cells in the nose to cause the illness COVID-19. But we know now that it doesn’t stop there. Clinicians and scientists have found […]
The Specter of Endothelial Injury in COVID-19
Studies signal that damage to the endothelium—cells that cover blood vessels like wallpaper—could underpin the thrombosis and inflammation induced by coronavirus infection. The endothelium as a common theme in COVID-19 […]
COVID-19: towards understanding of pathogenesis
Since the end of 2019, COVID-19 has caused considerable mortality and morbidity worldwide, and become a priority of the global society. Better understanding the pathogenesis of COVID-19 will provide important […]