Abstract Background. Long COVID, also termed post-COVID-19 condition or post-acute sequelae of SARS-CoV-2 infection (PASC), is a heterogeneous multisystem disorder that may follow mild or severe acute infection. Increasing evidence […]
Multidisciplinary Care Pathways for Long COVID Fatigue:
A Systems-Based Model Integrating Rehabilitation Medicine, Neuroimmunology, Autonomic Care, and Precision Phenotyping Abstract Background Long COVID, also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one […]
Recognition of Long COVID as a Heterogeneous Post-Infectious Syndrome
Toward a Multisystem Endotype Framework for Post–Acute SARS-CoV-2 Disease John Murphy, M.D., M.P.H., D.P.H. President Covid-19 Long-haul Foundation Abstract Long COVID (post–acute sequelae of SARS-CoV-2 infection, PASC) has emerged as […]
Persistent attenuation of lymphocyte subsets after mass SARS-CoV-2 infection
Zhengqi Jiang ∙ Tichao Shan∙ Yucan Li ∙ Heyu Ni ∙ et. al., DOI: 10.1016/j.ijid.2025.108287 External Link Also available on ScienceDirect External Link Highlights SARS-CoV-2 causes lasting immune dysregulation for over 20 months. The impact of SARS-CoV-2 on lymphocytes was especially severe in patients […]
Respiratory Viruses Like Flu Or COVID Could Cause ‘Sleeping’ Cancer Cells To Wake Up
StudyFinds Analysis, Steve Fink In A Nutshell AURORA, Colo. — Common respiratory infections like the flu and COVID-19 might jolt dormant cancer cells back to life in survivors, causing them to multiply […]
Discovery Explains Long COVID Breathing Problems
UVA Health researchers have made a discovery about the immune system that explains breathing problems in Long COVID. From left: Alexandra Kadl MD; Sepideh Dolatshahi, PhD; Lyndsey Muehling, PhD; Judith […]
CD56+ Monocytes and CD31+ Endothelial Cells Are Increased in Severe COVID-19 Disease
Abstract Immune response dysregulation plays a key role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. In this study, we evaluated immune and endothelial blood cell profiles of patients […]
A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice
Jide Tian1*Barbara J. Dillion2Jill Henley3et. al. Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate […]
‘Visionary’ study finds inflammation, evidence of Covid virus years after infection
By Isabella Cueto, 2024 Stat Reporting Remember when we thought Covid was a two-week illness? So does Michael Peluso, assistant professor of medicine at the University of California, San Francisco. He recalls […]
Human SARS-CoV-2 challenge uncovers local and systemic response dynamics
Rik G. H. Lindeboom, Kaylee B. Worlock, Lisa M. Dratva, et. al.Nature (2024) Abstract The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the dynamics of early cellular responses to […]