Systems Modeling Reveals Shared Metabolic Dysregulation and Novel Therapeutic Treatments in ME/CFS and Long COVID


Gong-Hua Li, Feifei Han, Qing-Peng Kong, Wenzhong Xiao, doi: https://doi.org/10.1101/2024.06.17.599450 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID are complex, multisystemic conditions that pose ongoing challenges to healthcare professionals. Emerging research suggests that ME/CFS and Long COVID exhibit overlapping metabolic symptoms, indicating possible shared metabolic dysfunctions. This study aims to systematically explore these shared metabolic disturbances and their potential treatments. Utilizing our […]

Laboratory Biomarkers for Diagnosis and Prognosis in COVID-19


Authors: Denise Battaglini, 1 , 2 , 3 Miquéias Lopes-Pacheco, 4 Hugo C. Castro-Faria-Neto, 5 Paolo Pelosi, 1 , 2 and Patricia R. M. Rocco 4 , 6 , 7 , * Front Immunol. 2022; 13: 857573.  Apr 27.  2022 doi: 10.3389/fimmu.2022.857573 PMCID: PMC9091347 PMID: 35572561 Abstract Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of clinical manifestations, with progression to multiorgan failure in the most severe cases. Several biomarkers can be altered […]