Category: B-cell

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

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Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2 , et. al., Front. Immunol., 03 March 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1344086 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant […]

Covid-19 has changed and so has our immunity. Here’s how to think about risk from the virus now

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By Brenda Goodman, CNN August 28, 2023 Experts say it’s less risky to catch Covid-19 than it used to be, but there are still good reasons not to treat it casually. Daly and Newton/The Image Bank RF/Getty ImagesCNN —  Covid-19 was never just another cold. We knew it was going to stick around and keep changing to try to […]

What Happens When You Still Have Long COVID Symptoms?

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BY KATHY KATELLA OCTOBER 27, 2023, Yale Medicine Yale’s Long COVID program aims to treat patients with lingering COVID-19 symptoms, such as fatigue, brain fog, and shortness of breath. Note: Information in this article was accurate at the time of original publication. Because information about COVID-19 changes rapidly, we encourage you to visit the websites of the […]

A blood test for long Covid is possible, a study suggests

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Scientists can now show key differences in the blood of those who recover from Covid — and those who don’t. Sept. 25, 2023, 11:01 AM EDT By Erika Edwards NBC Health More than three years into the pandemic, the millions of people who have suffered from long Covid finally have scientific proof that their condition is […]

Vaccine-induced immune thrombotic thrombocytopenia

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BLOOD SPOTLIGHT| APRIL 6, 2023 Douglas B. Cines, Andreas Greinacher Blood (2023) 141 (14): 1659–1665. https://doi.org/10.1182/blood.2022017696 Within the first months of the COVID-19 vaccination campaign, previously healthy recipients who developed severe thrombosis (often cerebral and/or splanchnic vasculature) and thrombocytopenia typically after adenoviral vector-based vaccination were identified. Similarities between this syndrome, vaccine-induced immune thrombotic thrombocytopenia (VITT), and heparin-induced […]

Post-COVID Interstitial Lung Disease—The Tip of the Iceberg

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Namrata Kewalramani, MD,a,b,∗ Kerri-Marie Heenan, MB Bch, BAO,c Denise McKeegan, MB Bch, BAO, MSc,c and Nazia Chaudhuri, MD, PhDd Immunol Allergy Clin North Am. 2023 May; 43(2): 389–410. Published online 2023 Mar3. doi: 10.1016/j.iac.2023.01.004 PMCID: PMC9982726PMID: 37055095 The proportion of symptomatic patients with post-coronavirus 2019 (COVID-19) condition (long COVID) represents a significant burden on the individual as well as on the health care systems. […]

Impacts of COVID on the immune system

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Authors: Lara Herrero, The Conversation Medical Xpress September 19, 2022 So you’ve had COVID and have now recovered. You don’t have ongoing symptoms and luckily, you don’t seem to have developed long COVID. But what impacts has COVID had on your overall immune system? It’s early days yet. But growing evidence suggests there are changes to […]

Bone Marrow Suppression Secondary to the COVID-19 Booster Vaccine: A Case Report

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TAuthors: oral Shastri 1, Navkiran Randhawa 2, Ragia Aly 3, Masood Ghouse 3 PMID: 35210894PMCID: PMC8863340DOI: 10.2147/JBM.S350290 J Blood Med.  2022; 13: 69–74.Published online 2022 Feb 18. doi: 10.2147/JBM.S350290 Abstract As of September 2021, SARS-CoV-2 booster shots became widely available in the US to ensure continued protection against the virus. A temporal relationship has been previously reported between the first or second dose of the COVID-19 vaccine […]

Bone Marrow Suppression Secondary to the COVID-19 Booster Vaccine: A Case Report

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Authors: Toral Shastri 1, Navkiran Randhawa 2, Ragia Aly 3, Masood Ghouse 3 PMID: 35210894 PMCID: PMC8863340DOI: 10.2147/JBM.S350290 Abstract As of September 2021, SARS-CoV-2 booster shots became widely available in the US to ensure continued protection against the virus. A temporal relationship has been previously reported between the first or second dose of the COVID-19 vaccine and the development of thrombocytopenia. However, adverse events related […]

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans

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Authors: Jackson S. Turner, Wooseob Kim, Elizaveta Kalaidina, Charles W. Goss, Adriana M. Rauseo, Aaron J. Schmitz, Lena Hansen, Alem Haile, Michael K. Klebert, Iskra Pusic, Jane A. O’Halloran, Rachel M. Presti & Ali H. Ellebedy  Nature volume 595, pages421–425 (2021) Abstract Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies1,2,3,4,5,6,7. Individuals who have recovered from COVID-19 have a substantially lower risk of reinfection with […]