Category: Animal Models

Endothelial cell damage is the central part of COVID-19 and a mouse model
induced by injection of the S1 subunit of the spike protein

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Authors: Gerard J. NuovoCynthia MagroToni ShafferHamdy AwadDavid SusterSheridan MikhailBing HeJean-Jacques MichailleBenjamin LiechtyEsmerina Tili Annals of Diagnostic Pathology ABS T R A C TNeurologic complications of symptomatic COVID-19 are common. Brain tissues from 13 autopsies of people who died of COVID-19 were examined. Cultured endothelial and neuronal cells were incubated with and wild type mice were […]

COVID-19 Virus Levels In Wastewater Have Dropped

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SEP 22, 2023 – 02:25 PM Authored by Naveen Athrappully via The Epoch Times  Wastewater COVID levels have shown a decline in recent weeks while the number of hospital admissions due to infections have seen an uptick. The levels of SARS-CoV-2 virus, which causes the COVID-19 infection, has dropped by 5 percent in the two weeks […]

Biodistribution of mRNA COVID-19 vaccines in human breast milk

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Nazeeh Hanna, Claudia Manzano De Mejia, Ari Heffes-Doon, Xinhua Lin, Bishoy Botros, Ellen Gurzenda, et al. September 19, 2023 DOI:https://doi.org/10.1016/j.ebiom.2023.104800 Summary Background COVID-19 mRNA vaccines play a vital role in the fight against SARS-CoV-2 infection. However, lactating women have been largely excluded from most vaccine clinical trials. As a result, limited research has been conducted […]

Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein

Posted on | Posted on John Murphy | Leave a Comment on Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein

Gerard J Nuovo 1, Cynthia Magro 2, Toni Shaffer 3, Hamdy Awad 4, David Suster 5, Sheridan Mikhail 3, Bing He 2, Jean-Jacques Michaille 6, Benjamin Liechty 2, Esmerina Tili 4 PMID: 33360731 PMCID: PMC7758180DOI: 10.1016/j.anndiagpath.2020.151682 Abstract Neurologic complications of symptomatic COVID-19 are common. Brain tissues from 13 autopsies of people who died of COVID-19 were examined. Cultured endothelial and neuronal cells were incubated with and wild type mice were injected IV with different spike subunits. In […]

Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

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Authors: Ibolya Rutkai, Meredith G. Mayer, Linh M. Hellmers, Bo Ning, Zhen Huang, Christopher J. Monjure, Carol Coyne, Rachel Silvestri, Nadia Golden, Krystle Hensley, Kristin Chandler, Gabrielle Lehmicke, Gregory J. Bix, Nicholas J. Maness, Kasi Russell-Lodrigue, Tony Y. Hu, Chad J. Roy, Robert V. Blair, Rudolf Bohm, Lara A. Doyle-Meyers, Jay Rappaport & Tracy Fischer  Nature Communications volume 13, Article number: 1745 (2022)  Published: 01 April 2022 Abstract Neurological manifestations are a significant complication of coronavirus disease (COVID-19), but underlying mechanisms aren’t well […]