Duke doctors share insights on the illness during a media briefing Authors: STEVE HARTSOE MARCH 9, 2022 IN RESEARCH, MEDICINE Thousands of COVID-19 survivors continue to grapple with symptoms many months after they were first infected. Brain fog, fatigue, even sexual dysfunction are among the symptoms people endure weeks and months after their acute COVID symptoms fade. On […]

Ophthalmic Manifestations Of Coronavirus (COVID-19)

Authors: Katherine Hu; Jay Patel; Cole Swiston; Bhupendra C. Patel.Author Information Last Update: May 19, 2021. Several reports of suspected ocular manifestations of coronavirus disease 2019 (COVID-19) have prompted investigations into ocular signs, symptoms, and transmission. This activity reviews the evaluation and management of ocular manifestations of COVID-19 and highlights the interprofessional team’s role in managing patients with this […]

COVID-19: A Mitochondrial Perspective

Authors: Pankaj Prasun 1 Coronavirus disease 2019 (COVID-19) is the worst public health crisis of the century. Although we have made tremendous progress in understanding the pathogenesis of this disease, a lot more remains to be learned. Mitochondria appear to be important in COVID-19 pathogenesis because of its role in innate antiviral immunity, as well as […]

COVID-19 Vasculopathy: Mounting Evidence for an Indirect Mechanism of Endothelial Injury

Authors: Roberto F. Nicosia,∗∗ Giovanni Ligresti,† Nunzia Caporarello,‡ Shreeram Akilesh,∗ and Domenico Ribatti§ Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular complications characterized by thrombosis of small, medium, and large vessels. Dysfunction of the vascular endothelium due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been implicated in the pathogenesis of the COVID-19 […]

Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

Authors: Matthias P Nägele 1, Bernhard Haubner 1, Felix C Tanner 1, Frank Ruschitzka 1, Andreas J Flammer 2 Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary complications such as acute myocardial injury, renal failure or thromboembolic events. A possible unifying explanation for these phenomena may be the presence of profound endothelial dysfunction and injury. This review provides an overview on the […]

Mutational Similarities Between SARS-CoV-2 and Its Predecessors

Authors: | Original story from University of Nebraska–Lincoln, Credit: Pete Linforth/ Pixabay New research from the University of Nebraska-Lincoln has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem to run in the family — or at least the genus of coronaviruses most dangerous to humans. After comparing the early evolution of SARS-CoV-2 against […]

Primed” for Infection: Cells Damaged by Chronic Lung Disease Can Result in Severe COVID

Authors: TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases. The results of a study by an international scientific team co-led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that — like pouring water atop […]

SARS-CoV-2 viral genomics

Authors: This analysis was performed primarily by Matt Olm ( in Justin Sonnenburg’s lab at Stanford University and Alex Crits-Christoph ( in Jill Banfield’s lab at University of California, Berkeley As viruses replicate within their hosts during infection, they mutate and accrue genetic diversity in their populations. These populations are usually shared as a single […]

Covid-19: links between genes and disease severity

Authors: Bolzano research centre In March 2020, thousands of scientists around the world joined forces to investigate the questions at the forefront of the medical debate on the pandemic: what genetic factors influence the severity of Covid-19 infections and why do some people develop a serious illness that requires hospitalisation while others have mild or […]


Authors: Cleveland Clinic What is dysautonomia? Dysautonomia is a general term for a group of disorders that share a common problem – that is, an autonomic nervous system (ANS) that doesn’t function as it should. The ANS is the part of the nervous system that controls involuntary body functions (functions you don’t consciously control) like […]