Covid deaths no longer overwhelmingly among unvaccinated as toll on elderly grows


Authors: Fenit Nirappil and Dan Keating, The Washington PostApril 29, 2022 Unvaccinated people accounted for the overwhelming majority of deaths in the United States throughout much of the coronavirus pandemic. But that has changed in recent months, according to a Washington Post analysis of state and federal data. The pandemic’s toll is no longer falling almost […]

SARS-CoV-2 mRNA Vaccination-Associated Myocarditis in Children Ages 12-17: A Stratified National Database Analysis


Authors: RALPH TURCHIANO   SEPTEMBER 8, 2021 •  Abstract Establishing the rate of post-vaccination cardiac myocarditis in the 12-15 and 16-17-year-old population in the context of their COVID-19 hospitalization risk is critical for developing a vaccination recommendation framework that balances harms with benefits for this patient demographic. Design, Setting and Participants: Using the Vaccine Adverse Event Reporting […]

Does this enzyme raise the chance of COVID-related death?


Researchers discovered an enzyme that is genetically related to a key enzyme in snake venom and was found in COVID-19 fatalities in doses 20 times the safe amount. By JERUSALEM POST STAFF   SEPTEMBER 4, 2021 19:37 A study from the University of Arizona discovered that an enzyme with a key role in severe inflammation may be a […]

First case of postmortem study in a patient vaccinated against SARS-CoV-2


Author:TorstenHansenaUlfTitzeaNidhi Su AnnKulamadayil-HeidenreichbSabineGlombitzacJohannes, et. al. Highlights • We report on a patient with a single dose of vaccine against SARS-CoV-2. • He developed relevant serum titer levels but died 4 weeks later. • By postmortem molecular mapping, we found viral RNA in nearly all organs examined. • However, we did not observe any characteristic morphological features of COVID-19. • […]

Prophylaxis against covid-19: living systematic review and network meta-analysis


Authors: Jessica J Bartoszko, methodologist,1 ,*Reed A C Siemieniuk, methodologist, internist,1 ,*Elena Kum, methodologist,1 ,*Anila Qasim, methodologist,1 ,*Dena Zeraatkar, methodologist,1 ,*Long Ge, methodologist,2 ,*Mi Ah Han, methodologist,3Behnam Sadeghirad, assistant professor,1,4Arnav Agarwal, methodologist, internist,1,5Thomas Agoritsas, methodologist, internist,1,6Derek K Chu, methodologist, immunologist,1,7Rachel Couban, librarian,4Andrea J Darzi, methodologist,1Tahira Devji, methodologist,1Maryam Ghadimi, methodologist,1Kimia Honarmand, methodologist, critical care physician,8Ariel Izcovich, methodologist, internist,9Assem Khamis, data analyst,10Francois Lamontagne, methodologist, critical care physician,11Mark Loeb, methodologist, infectious disease physician,1,7Maura Marcucci, methodologist, internist,1,7Shelley L McLeod, methodologist, assistant professor,12,13Sharhzad […]

Characteristics of SARS-CoV-2 and COVID-19


Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi  Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we […]

The incidence, clinical characteristics, and outcomes of pneumothorax in hospitalized COVID-19 patients: A systematic review


Authors: Woon H. Chong,a,⁎Biplab K. Saha,bKurt Hu,c and Amit Chopraa Abstract Background Pneumothorax has been frequently described as a complication of COVID-19 infections. Objective In this systematic review, we describe the incidence, clinical characteristics, and outcomes of COVID-19-related pneumothorax. Methods Studies were identified through MEDLINE, Pubmed, and Google Scholar databases using keywords of “COVID-19,” “SARS-CoV-2,” “pneumothorax,” “pneumomediastinum,” […]

Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms – a systematic review and meta-analysis


Authors: Endang Mutiawati, Conceptualization, Data Curation, Resources, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,a,1,2Marhami Fahriani, Conceptualization, Data Curation, Investigation, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,3Sukamto S. Mamada, Data Curation, Investigation, Validation, Writing – Review & Editing,4Jonny Karunia Fajar, Conceptualization, Formal Analysis, Investigation, Methodology, Writing – Review & Editing,3,5Andri Frediansyah, Data Curation, Investigation, Writing – Original Draft Preparation, Writing – Review & Editing,6Helnida Anggun Maliga, Data Curation, Investigation, Validation, Writing – Review & Editing,7Muhammad Ilmawan, Data Curation, Investigation, Validation, Writing […]

Clinical utility of cardiac troponin measurement in COVID-19 infection


Authors: David C Gaze 1 2 Abstract The novel coronavirus SARS-CoV-2 causes the disease COVID-19, a severe acute respiratory syndrome. COVID-19 is now a global pandemic and public health emergency due to rapid human-to-human transmission. The impact is far-reaching, with enforced social distancing and isolation, detrimental effects on individual physical activity and mental wellbeing, education in the […]

Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mortality


Authors: Baher Al Abbasi 1, Pedro Torres 1, Fergie Ramos-Tuarez 2, Nakeya Dewaswala 1, Ahmed Abdallah 1, Kai Chen 1, Mohamed Abdul Qader 1, Riya Job 1, Samar Aboulenain 1, Karolina Dziadkowiec 1, Huzefa Bhopalwala 3, Jesus E Pino 2, Robert D Chait 2 Abstract Background: The number of fatalities due to coronavirus disease 2019 (COVID-19) is escalating with more than 800,000 deaths globally. The scientific community remains in urgent need of prognostic tools to determine the probability of survival in […]