Category: Organ Failure

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 infection and persistence in the human body and brain at autopsy

Authors: by Covid Strategies | Dec 14, 2022 | Science & News Nature Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1,2,3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 (refs. 4,5). However, the burden of infection outside the respiratory tract and time to viral clearance […]

COVID-19 Autopsies Uncover Ways The Coronavirus Kills April 29, 2021 Angus Chen

Posted on | Posted on John Murphy | Leave a Comment on COVID-19 Autopsies Uncover Ways The Coronavirus Kills April 29, 2021 Angus Chen

When patients become severely ill with COVID-19, the coronavirus infiltrates deep into the lungs and causes mayhem on the tissues that line the organ. The infection can cause swelling, and fluid and debris can start to fill the lungs. It can feel like drowning on dry land. Patients who remember being intubated sometimes describe the […]

Autopsy-Based Pulmonary and Vascular Pathology: Pulmonary Endotheliitis and Multi-Organ Involvement in COVID-19 Associated Deaths

Posted on | Posted on John Murphy | Leave a Comment on Autopsy-Based Pulmonary and Vascular Pathology: Pulmonary Endotheliitis and Multi-Organ Involvement in COVID-19 Associated Deaths

Authors: artina Haberecker University Hospital Zürich Esther I Schwarz University of Zurich Peter Steiger University of Zurich Karl Frontzek University of ZurichSeptember 2021 Respiration 101(2):1-11 DOI:10.1159/000518914License CC BY-NC 4.0 Abstract and Figures Background: Findings from autopsies have provided evidence on systemic microvascular damage as one of the underlying mechanisms of Coronavirus disease 2019 (CO-VID-19). The aim […]

COVID-19 Can Infect and Harm Digestive Organs

Posted on | Posted on John Murphy | Leave a Comment on COVID-19 Can Infect and Harm Digestive Organs

Authors: E.J. Mundell  The coronavirus isn’t just attacking the lungs: New research shows it’s causing harm to the gastrointestinal tract, especially in more advanced cases of COVID-19. A variety of imaging scans performed on hospitalized COVID-19 patients showed bowel abnormalities, according to a study published online May 11 in Radiology. Many of the effects were severe and […]

Intestinal Damage in COVID-19: SARS-CoV-2 Infection and Intestinal Thrombosis

Posted on | Posted on John Murphy | Leave a Comment on Intestinal Damage in COVID-19: SARS-CoV-2 Infection and Intestinal Thrombosis

Authors: Xiaoming Wu1, Haijiao Jing1, Chengyue Wang1, Yufeng Wang1, Nan Zuo1, Tao Jiang2*, Valerie A. Novakovic3 and Jialan Shi1,3,4* Front. Microbiol., 22 March 2022 | https://doi.org/10.3389/fmicb.2022.860931 The intestinal tract, with high expression of angiotensin-converting enzyme 2 (ACE2), is a major site of extrapulmonary infection in COVID-19. During pulmonary infection, the virus enters the bloodstream forming viremia, which infects and damages extrapulmonary organs. Uncontrolled viral […]

Review of Mesenteric Ischemia in COVID-19 Patients

Posted on | Posted on John Murphy | Leave a Comment on Review of Mesenteric Ischemia in COVID-19 Patients

Authors: Amit Gupta, Oshin Sharma, Kandhala Srikanth, Rahul Mishra, Amoli Tandon & Deepak Rajput  Indian Journal of Surgery (2022) Published: 11 March 2022 Abstract The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become a pandemic that has spread to nearly every country in the world. Through October 11, 2021, more than 23 billion confirmed cases and 4.8 million […]

Prevalence of organ impairment in Long COVID patients 6 and 12 months after initial symptoms

Posted on | Posted on John Murphy | Leave a Comment on Prevalence of organ impairment in Long COVID patients 6 and 12 months after initial symptoms

Authors:  Pooja Toshniwal PahariaMar 24 2022Reviewed by Danielle Ellis, B.Sc. In a recent study posted to the medRxiv* preprint server, researchers assessed the prevalence of organ impairment in long coronavirus disease 2019 (COVID-19) six months and a year post-COVID-19 at London and Oxford. Multi-organ impairment associated with long COVID-19 is a significant health burden. Standardized multi-organ evaluation […]

Pancreatic damage in COVID‐19: Why? How?

Posted on | Posted on John Murphy | Leave a Comment on Pancreatic damage in COVID‐19: Why? How?

Authors: Ferhat Bacaksız, 1 Berat Ebik, 1 Nazım Ekin, 1 and Jihat Kılıc 2 Int J Clin Pract. 2021 Aug 6 : e14692.doi: 10.1111/ijcp.14692 [Epub ahead of print] PMCID:  PMC8420122PMID: 34331821 Abstract Object We aimed to evaluate the elevation of amylase and lipase enzymes in coronavirus disease 2019 (COVID‐19) patients and their relationship with the severity of COVID‐19. Method In this study, 1378 patients with COVID‐19 infection […]

Why are we vaccinating children against COVID-19?

Posted on | Posted on John Murphy | Leave a Comment on Why are we vaccinating children against COVID-19?

Authors: Ronald N.Kostoffa DanielaCalinab DarjaKanducc Michael B.Briggsd Panayiotis Vlachoyiannopoulose Andrey A.Svistunovf AristidisTsatsakisg Highlights • Bulk of COVID-19 per capita deaths occur in elderly with high comorbidities. •Per capita COVID-19 deaths are negligible in children. •Clinical trials for these inoculations were very short-term. •Clinical trials did not address long-term effects most relevant to children. •High post-inoculation deaths reported […]

Gastrointestinal perforation secondary to COVID-19

Posted on | Posted on John Murphy | Leave a Comment on Gastrointestinal perforation secondary to COVID-19

Authors: Case reports and literature review Reem J. Al Argan, MBBS, SB-Med, SF-Endo, FACE, ECNU,∗Safi G. Alqatari, MBBS, MRCPI, MMedSc, CFP (Rheum), Abir H. Al Said, MBBS, SB-Med, CFP (Pulmo.), Raed M. Alsulaiman, MBBS, SB-Med, Abdulsalam Noor, MBBS, SB-Med, ArBIM, SF-Nephro, Lameyaa A. Al Sheekh, MD, SB-med, and Feda’a H. Al Beladi, MD Introduction: Corona virus disease-2019 (COVID-19) presents primarily […]