Category: D-dimer

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Posted on | Posted on John Murphy | Leave a Comment on Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group,  Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

Diagnosis of venous thromboembolic diseases in people with covid-19: summary of updated NICE guidance

Posted on | Posted on John Murphy | Leave a Comment on Diagnosis of venous thromboembolic diseases in people with covid-19: summary of updated NICE guidance

BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2204 (Published 12 October 2023)Cite this as: BMJ 2023;383:p2204, Sarah Boyce, senior technical analyst1,  Emma McFarlane, Susan Harrison, Terry McCormack What you need to know In venous thromboembolism, a blood clot usually forms in the deep veins of the legs or pelvis. This is known as deep vein thrombosis, and the blood clot can dislodge from these sites, […]

Blood Clotting Proteins Might Help Predict Long COVID Brain Fog

Posted on | Posted on John Murphy | Leave a Comment on Blood Clotting Proteins Might Help Predict Long COVID Brain Fog

New research suggests that blood clotting from COVID infections could contribute to long-term brain fog and other cognitive issues By Sara Reardon on September 1, 2023 Scientific American Many people who have long COVID—a condition in which health issues persist months after infection—report struggling with “brain fog,” recurring memory and concentration lapses that make it difficult­­ to function […]

UK scientists find link between proteins related to blood clots and long Covid

Posted on | Posted on John Murphy | Leave a Comment on UK scientists find link between proteins related to blood clots and long Covid

Biomarker discovery indicates that sufferers from brain fog and fatigue post-virus could be treated with anticoagulants Oksana Pyzik 31 Aug 2023 The Guardian Scientists have identified molecular signatures in the blood that are linked to brain fog, other cognitive problems and fatigue in patients who are diagnosed with long Covid after catching the virus. Raised levels of […]

Vaccine-induced immune thrombotic thrombocytopenia

Posted on | Posted on John Murphy | Leave a Comment on Vaccine-induced immune thrombotic thrombocytopenia

BLOOD SPOTLIGHT| APRIL 6, 2023 Douglas B. Cines, Andreas Greinacher Blood (2023) 141 (14): 1659–1665. https://doi.org/10.1182/blood.2022017696 Within the first months of the COVID-19 vaccination campaign, previously healthy recipients who developed severe thrombosis (often cerebral and/or splanchnic vasculature) and thrombocytopenia typically after adenoviral vector-based vaccination were identified. Similarities between this syndrome, vaccine-induced immune thrombotic thrombocytopenia (VITT), and heparin-induced […]

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Posted on | Posted on John Murphy | Leave a Comment on Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

Laboratory Biomarkers for Diagnosis and Prognosis in COVID-19

Posted on | Posted on John Murphy | Leave a Comment on Laboratory Biomarkers for Diagnosis and Prognosis in COVID-19

Authors: Denise Battaglini, 1 , 2 , 3 Miquéias Lopes-Pacheco, 4 Hugo C. Castro-Faria-Neto, 5 Paolo Pelosi, 1 , 2 and Patricia R. M. Rocco 4 , 6 , 7 , * Front Immunol. 2022; 13: 857573.  Apr 27.  2022 doi: 10.3389/fimmu.2022.857573 PMCID: PMC9091347 PMID: 35572561 Abstract Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of clinical manifestations, with progression to multiorgan failure in the most severe cases. Several biomarkers can be altered […]

Acute Mesenteric Ischemia in COVID-19 Patients

Posted on | Posted on John Murphy | Leave a Comment on Acute Mesenteric Ischemia in COVID-19 Patients

Authors: Dragos Serban 1,2,*† , Laura Carina Tribus 3,4,†, Geta Vancea 1,5,† , Anca Pantea Stoian, Ana Maria Dascalu 1,* Andra Iulia Suceveanu 6Ciprian Tanasescu 7,8, Andreea Cristina Costea 9 Mihail Silviu Tudosie 1, Corneliu Tudor 2, Gabriel Andrei Gangura 1,10, Lucian Duta 2 and Daniel Ovidiu Costea 6,11, Abstract: Acute mesenteric ischemia is a […]

The coagulopathy, endotheliopathy, and vasculitis of COVID-19

Posted on | Posted on John Murphy | Leave a Comment on The coagulopathy, endotheliopathy, and vasculitis of COVID-19

Authors: Toshiaki Iba 1, Jean Marie Connors 2, Jerrold H Levy 3 PMID: 32918567 PMCID: PMC7486586 DOI: 10.1007/s00011-020-01401-6 Abstract Background COVID-19-associated coagulopathy (CAC) characterized by the elevated D-dimer without remarkable changes of other global coagulation markers is associated with various thrombotic complications and disease severity. The purpose of this review is to elucidate the pathophysiology of this unique coagulopathy. Methods The authors performed […]

Role of von Willebrand Factor in COVID-19 Associated Coagulopathy

Posted on | Posted on John Murphy | Leave a Comment on Role of von Willebrand Factor in COVID-19 Associated Coagulopathy

Authors: Zhen W Mei, Xander M R van Wijk, Huy P Pham, Maximo J Marin The Journal of Applied Laboratory Medicine, Volume 6, Issue 5, September 2021, Pages 1305–1315,  https://doi.org/10.1093/jalm/jfab042Published: 13 June 2021 Abstract Background COVID-19, the disease caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) can present with symptoms ranging from none to severe. Thrombotic events occur […]