Dynamic Assessment of Hematological Parameters as Predictive Biomarkers for Disease Severity and Prognosis in COVID-19 Patients: A Longitudinal Study


Aparna P. Patange • Jabbar V. Desai • Bhupal Pujari • Aparna Marwah • Animesh Dey, Published: July 01, 2024, DOI: 10.7759/cureus.63593  Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to substantial morbidity and mortality worldwide. Hematological abnormalities are common in COVID-19 patients and play a significant role in disease pathogenesis and prognosis. Objective: […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches


Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2 , et. al., Front. Immunol., 03 March 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1344086 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant […]

Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence


Rushabh Parekh • Virendra Athavale • Saili Kelshikar, : June 11, 2024, DOI: 10.7759/cureus.62136  Abstract Since the start of the SARS-CoV-2 pandemic, which is otherwise known as the worldwide coronavirus disease, 2019, has had a well-established pro-thrombotic character. Patients often first exhibit respiratory symptoms, and those whose severity increases eventually develop acute hypoxic respiratory failure. The systemic hypercoagulable condition and arterial/venous […]

Platelet Indices as Novel Surrogate Markers for the Prognosis of COVID-19 Infection: An Observational Study


Vivek Lahane • Sourya Acharya • Samarth Shukla • et. al. June 12, 2024 DOI: 10.7759/cureus.62243  Abstract Background  The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe acute respiratory illness accountable for causing the coronavirus disease 2019 (COVID-19) illness. Thrombotic issues, acute respiratory distress syndrome (ARDS), and cytokine storm are significant contributors to morbidity and mortality in patients with COVID-19. Elevated D-dimer […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches


Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc, et. al. , Frontiers in Medicine The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant proportion of them continue to experience health issues weeks, months […]

Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence


Rushabh Parekh • Virendra Athavale • Saili Kelshikar, Published: June 11, 2024 DOI: 10.7759/cureus.62136  Abstract Since the start of the SARS-CoV-2 pandemic, which is otherwise known as the worldwide coronavirus disease, 2019, has had a well-established pro-thrombotic character. Patients often first exhibit respiratory symptoms, and those whose severity increases eventually develop acute hypoxic respiratory failure. The systemic hypercoagulable condition and arterial/venous […]

Exploring the Clinical Features, Management of Hypertension, and Predictors of Severity in Hospitalized Hypertensive COVID-19 Patients


Abstract Background Hypertension significantly contributes to the severity, prolonged hospitalization, the need for intensive care, and mortality of COVID-19 patients. However, the data is still evolving. This study investigated the predictors of severity among hypertensive COVID-19 patients. Methodology This cohort study included 333 hospitalized hypertensive COVID-19 patients at the Indus Hospital, Karachi, Pakistan, from April […]

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization


Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group,  Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

Diagnosis of venous thromboembolic diseases in people with covid-19: summary of updated NICE guidance


BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2204 (Published 12 October 2023)Cite this as: BMJ 2023;383:p2204, Sarah Boyce, senior technical analyst1,  Emma McFarlane, Susan Harrison, Terry McCormack What you need to know In venous thromboembolism, a blood clot usually forms in the deep veins of the legs or pelvis. This is known as deep vein thrombosis, and the blood clot can dislodge from these sites, […]

Blood Clotting Proteins Might Help Predict Long COVID Brain Fog


New research suggests that blood clotting from COVID infections could contribute to long-term brain fog and other cognitive issues By Sara Reardon on September 1, 2023 Scientific American Many people who have long COVID—a condition in which health issues persist months after infection—report struggling with “brain fog,” recurring memory and concentration lapses that make it difficult­­ to function […]