Systems Modeling Reveals Shared Metabolic Dysregulation and Novel Therapeutic Treatments in ME/CFS and Long COVID


Gong-Hua Li, Feifei Han, Qing-Peng Kong, Wenzhong Xiao, doi: https://doi.org/10.1101/2024.06.17.599450 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID are complex, multisystemic conditions that pose ongoing challenges to healthcare professionals. Emerging research suggests that ME/CFS and Long COVID exhibit overlapping metabolic symptoms, indicating possible shared metabolic dysfunctions. This study aims to systematically explore these shared metabolic disturbances and their potential treatments. Utilizing our […]

New Broad Definition of Long COVID


Miriam E. Tucker, 2024 A new broadly inclusive definition of long COVID from the National Academies of Sciences, Engineering, and Medicine (NASEM) has been developed with the aim of improving consistency, documentation, and treatment for both adults and children. According to the 2024 NASEM definition of long COVID issued on June 11, 2024, “Long COVID is an […]

Orthostatic Intolerance in Long-Haul COVID after SARS-CoV-2: A Case-Control Comparison with Post-EBV and Insidious-Onset Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients


C. (Linda) M. C. van Campen* and Frans C. Visser, Kenneth J. Friedman, Academic Editor, Patricia A. Fennell, Academic Editor, Derek F. H. Pheby, Academic Editor, Evan Spivack, Academic Editor, James M. Oleske, Academic Editor, Nancy Klimas, Academic Editor, Pawel Zalewski, Academic Editor, and Susan M. Levine, Academic Editor Healthcare (Basel). 2022 Oct; 10(10): 2058. Published online 2022 Oct 17. doi: 10.3390/healthcare10102058, PMCID: PMC9602265,PMID: 36292504 Abstract Background: As complaints of long-haul […]

Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments


The causes of long COVID, which disables millions, may come together in the brain and nervous system  Author: Stephani Sutherland   March 1, 2023 Tara Ghormley has always been an overachiever. She finished at the top of her class in high school, graduated summa cum laude from college and earned top honors in veterinary school. She […]

Long COVID: The hunt for causes and cures


With so many treatment candidates, researchers work to gain more clarity by Shi En Kim September 11, 2023 | A version of this story appeared in Volume 101, Issue 30 Hannah Davis misses her old self. Like so many people around the world, she has seen her life upended by long COVID, which has made many once-routine […]

Coronavirus and the Nervous System


What is SARS-CoV-2 and COVID-19? National Institute of Neurological Disorders and Stroke Coronaviruses are common causes of usually mild to moderate upper respiratory tract illnesses like the common cold, with symptoms that may include runny nose, fever, sore throat, cough, or a general feeling of being ill. However, a new coronavirus called Severe Acute Respiratory […]