John Murphy, M.D., M.P.H., D.P.H. President COVID-19 Long-haul Foundation Abstract Long COVID, also termed post-COVID condition or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one of the most […]
Understanding metformin use and Long COVID and ME/CFS
RECOVER researchers shared how the prescription drug metformin may reduce the risk of Long COVID and presented research examining the risk of developing myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) after a […]
Mitochondrial Depletion and Long-COVID: Etiology, Pathophysiology, Diagnostics, and Clinical Implications
John Murphy, M.D., MPH, D.P.H., President The COVID19 Long-haul Foundation AbstractA growing body of evidence implicates mitochondrial dysfunction — including depletion of mitochondrial DNA (mtDNA), loss of mitochondrial membrane potential, […]
COVID Fatigue: Etiology, Genomics, Physiology, Pathology, Neurobiology, Sleep Disturbance, Treatment, and Prognosis
John Murphy, CEO COVID-19 Long-haul Foundation Abstract Fatigue is the most prevalent and disabling symptom among survivors of SARS‑CoV‑2 infection, persisting in a substantial proportion of patients months to years […]
Data-driven RECOVER research produces new discoveries about Long COVID.
This installment of the RECOVER Research Update—a summary of recent findings published every 3 months—focuses on innovative research using patient information contained in electronic health records (EHRs). Each time a person […]
Neuroimmune Convergence in Narcolepsy and Long COVID-Associated ME/CFS
John Murphy, The COVID Long-haul Foundation Introduction Narcolepsy and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), particularly as it manifests in the context of Long COVID, represent two distinct clinical entities with […]
First proposed blood test for chronic fatigue syndrome: what scientists think
A blood test has achieved 96% accuracy in diagnosing the condition in a small study of individuals. What does the test detect, and is it a biomarker of the condition? […]
NIH-funded study finds cases of ME/CFS increase following SARS-CoV-2
New findings from the National Institutes of Health’s (NIH) Researching COVID to Enhance Recovery (RECOVER) Initiative suggest that infection with SARS-CoV-2, the virus that causes COVID-19, may be associated with […]
The Lingering Pandemic: Mapping the Arc of Long COVID and the Search for Recovery
By John Murphy, The COVID 19 Long-haul Foundation Introduction: A Pandemic That Didn’t End When the world first confronted SARS-CoV-2 in early 2020, the prevailing narrative was one of acute […]
Exploration of Intersections and Divergences of Long COVID and Chronic Fatigue Syndrome
Joao A. Kouyoumdjian • Leticia A. Yamamoto • Carla R. Graca, DOI: 10.7759/cureus.90607 Abstract Background: Fatigue is the most common symptom of Long COVID (LC), defined by persistent or newly emerging symptoms that develop at least three […]