Authors: Sonu Bhaskar,1,2,3,* Akansha Sinha,1,4 Maciej Banach,1,5,6,7 Shikha Mittoo,1,8 Robert Weissert,1,9 Joseph S. Kass,1,10 Santhosh Rajagopal,1,11 Anupama R. Pai,1,12 and Shelby Kutty1,13,14 Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness in many conditions […]
COVID-19 cytokine storm: The anger of inflammation
Authors: Mehdi Mahmudpour 1, Jamshid Roozbeh 2, Mohsen Keshavarz 1, Shokrollah Farrokhi 3, Iraj Nabipour 4 Patients with COVID-19 who require ICU admission might have the cytokine storm. It is a state of out-of-control release of a variety of […]
Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Authors: Yujun Tang,† Jiajia Liu,† Dingyi Zhang, Zhenghao Xu, Jinjun Ji,* and Chengping Wen* Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the […]
SARS-CoV-2 infection: The role of cytokines in COVID-19 disease
Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of […]
Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment
Authors: Mehmet Soy 1, Gökhan Keser 2, Pamir Atagündüz 3, Fehmi Tabak 4, Işık Atagündüz 5, Servet Kayhan COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes only mild symptoms in the majority of the cases, […]
In the lab, scientists identify possible COVID-19 treatment
Authors: St. Jude Children’s Research Hospital The COVID-19 pandemic continues to cause significant illness and death while treatment options remain limited. St. Jude Children’s Research Hospital scientists have discovered a […]
Accumulating evidence suggests anti-TNF therapy needs to be given trial priority in COVID-19 treatment
Authors: Philip C Robinson, Duncan Richards, Helen L Tanner, Marc Feldmann The COVID-19 pandemic continues to wreak havoc on global health-care systems and to claim an increasing number of lives. […]
TNF Biologics and COVID-19: What Autoimmune Patients Need to Know
Authors: If you’re taking a type of medication known as tumor necrosis factor inhibitors, also called anti-TNF or TNFis, you may be wondering how these drugs could impact your chances […]
Pathways in the Pathophysiology of Coronavirus 19 Lung Disease Accessible to Prevention and Treatment
Authors: Michael Eisenhut 1, Jae Il Shin 2 Background: In COVID 19 related lung disease, which is a leading cause of death from this disease, cytokines like tumor necrosis factor-alpha (TNF alpha) may be […]
Integrative clinical, genomics and metabolomics data analysis for mainstream precision medicine to investigate COVID-19
Authors: Zeeshan Ahmed, Saman Zeeshan, David J Foran, Lawrence C Kleinman, Fredric E Wondisford, XinQi Dong Crrespondence to Dr Zeeshan Ahmed, Rutgers Institute for Health, Health Care Policy and Aging Research, Rutgers University, […]