Sex-Based and Genetic Vulnerabilities: Hormonal Modulation, IL-6 Polymorphisms, HLA Factors, and Personalized Medicine Implications

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a striking female predominance and heterogeneous symptom profiles. Emerging evidence suggests…[...]

Read More

Persistent SARS-CoV-2 Spike Protein: Genomic Modulation, Immune Dysregulation, and Impaired Antibody Maturation

Author: John Murphy, CEO COVID 19 Long-haul Foundation Abstract The SARS-CoV-2 spike glycoprotein, central to viral entry and the target of mRNA vaccine platforms, has emerged as a persistent antigen…[...]

Read More

Genomic Convergence: Emerging Pathways, Mechanisms, and Druggable Targets in Precision Medicine for COVID Long-haul Research

Author: John Murphy, CEO COVID-19 Long-haul Foundation Abstract The past three years have witnessed an unprecedented acceleration in genomic discovery, driven by advances in single-cell sequencing, spatial transcriptomics, and integrative…[...]

Read More