Role of MicroRNA-21 in Regulating Intracellular Pathways Associated With Phagocytosis in Human Macrophages: An In Vitro Study
Natsuki Anada • Yoshinobu Nakayama • Jun Takeshita • Kyoko Kageyama • Hiroatsu Sakamoto • Takahiko Kamibayashi • Yasufumi Nakajima 2024, DOI: 10.7759/cureus.63736 Abstract Introduction The efficient clearance of bacteria by macrophages is crucial for the timely resolution of inflammation. In this study, we investigated the role of microRNA-21 (miR-21)-induced phagocytosis and its intracellular signaling pathways in human macrophages in vitro. Methods Human peripheral blood mononuclear cells (PBMCs) were […]