A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

February 8, 2025 | John Murphy | Leave a Comment

A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

Jide Tian1*Barbara J. Dillion2Jill Henley3et. al. Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate…[...]

October 16, 2024 | John Murphy | Leave a Comment

Role of MicroRNA-21 in Regulating Intracellular Pathways Associated With Phagocytosis in Human Macrophages: An In Vitro Study

Natsuki Anada • Yoshinobu Nakayama • Jun Takeshita • Kyoko Kageyama • Hiroatsu Sakamoto • Takahiko Kamibayashi • Yasufumi Nakajima 2024, DOI: 10.7759/cureus.63736 Abstract Introduction The efficient clearance of bacteria by macrophages is crucial for the timely resolution of inflammation. In this study,…[...]

October 9, 2023 | John Murphy | Leave a Comment

Scientists Gain Insight Into COVID’s Heart Impact

(02 October 2023 Newsmax Health Day New research shows the COVID-19 virus can directly infect coronary arteries, inflaming fatty plaque inside them, which can increase the risk of heart disease…[...]

August 13, 2021 | John Murphy | Leave a Comment

Trained Innate Immunity, Epigenetics, and Covid-19

Authors: Alberto Mantovani, M.D., and Mihai G. Netea, M.D. Innate immunity is mediated by different cell types and cell-associated or fluid-phase pattern-recognition molecules and plays a key role in tissue repair…[...]