Category: Inflammation

Role of MicroRNA-21 in Regulating Intracellular Pathways Associated With Phagocytosis in Human Macrophages: An In Vitro Study

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Natsuki Anada • Yoshinobu Nakayama • Jun Takeshita • Kyoko Kageyama • Hiroatsu Sakamoto • Takahiko Kamibayashi • Yasufumi Nakajima 2024, DOI: 10.7759/cureus.63736  Abstract Introduction The efficient clearance of bacteria by macrophages is crucial for the timely resolution of inflammation. In this study, we investigated the role of microRNA-21 (miR-21)-induced phagocytosis and its intracellular signaling pathways in human macrophages in vitro. Methods Human peripheral blood mononuclear cells (PBMCs) were […]

Inflammation: The Body’s ‘Fire’ Burns Threats, But Things Go Wrong When It Smolders

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Authored by Flora Zhao via The Epoch Times Many people experience chronic inflammation without even knowing it, Arch G. Mainous III, a professor at the University of Florida (UF) College of Medicine, told The Epoch Times. A large-scale study published in Frontiers in Medicine in 2024 showed that among adults in the United States, almost 35 percent had […]

The beneficial and pathogenic roles of complement in COVID-19

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Alfred H.J. Kim, MD, PhD, Xiaobo Wu, MD and John P. Atkinson, MD Cleveland Clinic Journal of Medicine October 2020, DOI: https://doi.org/10.3949/ccjm.87a.ccc065 ABSTRACT We briefly summarize the complement system and its functions in immunity and disease. We present data supporting the requirement of complement to resolve COVID-19, and discuss how complement overactivation later in severe disease could drive multiorgan damage characteristic of fatal COVID-19. INTRODUCTION The […]

Clinical trial aims to find out if low-dose lithium could treat long COVID

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By ELLEN GOLDBAUM Published January 11, 2023  “I just kept hearing the same story: that within days they were noticing satisfactory benefit. ” Thomas J. Guttuso Jr., professor, Department of Neurology, University of Buffalo Adults experiencing long COVID may be interested in a new University at Buffalo clinical trial that is testing low-dose lithium as a potential treatment. […]

New long COVID study uncovers high inflammation in patients as Senate calls for more research on ‘crisis’

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The study followed 113 patients at four different hospitals in Switzerland. By Ashley Riegle, ABC News, January 24, 2024, 8:10 PM , The life of COVID-19 long-haulers For these people, surviving the coronavirus was the just beginning of fighting long-term symptoms. A new study in Science is shining a light on the continuing impact of long COVID, […]

COVID-19 Can Remain Undetected In Lungs For 18 Months: Study

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DEC 14, 2023 – Authored by Amie Dahnke via The Epoch Times  The COVID-19 virus can remain in the lungs for months after an individual has been infected—even though it may be undetected by over-the-counter (OTC) tests, a new study finds. The findings, established by a research team from the Institut Pasteur in France and […]

Dermatology and COVID-19

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Kanade Shinkai, MD, PhD1,2; Anna L. Bruckner, MD, MSCS3,JAMA. 2020;324(12):1133-1134. doi:10.1001/jama.2020.15276 Even early in the coronavirus disease 2019 (COVID-19) pandemic, it was clear that dermatologists had an important role in the management of patients. Although initial case series rarely documented skin changes, possibly due to the inability to perform a complete skin examination, subsequent research has suggested significantly higher rates of […]

Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

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Héctor Hernández-Parra1,2 Octavio Daniel Reyes-Hernández3 Gabriela Figueroa-González4 Manuel González-Del Carmen5 Maykel González-Torres6 Sheila I. Peña-Corona2 Benjamín Florán7 Hernán Cortés8* Gerardo Leyva-Gómez2* https://pubmed.ncbi.nlm.nih.gov/36998270/ Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease (COVID-19), including stroke, ataxia, meningitis, encephalitis, and cognitive impairment. These alterations can cause serious sequelae or death and are associated with the entry of SARS-CoV-2 into the Central Nervous System […]

COVID Tongue: How a Swollen Tongue Could Indicate COVID-19

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Should you be examining your tongue? Here’s how to tell if it’s COVID tongue and how to treat it. By  Korin Miller September 22, 2023; Medically reviewed by  Michael Menna, DO HEALTH You may have heard of COVID-19 causing loss of taste and smell, COVID toes, and unusual skin rashes, but did you know COVID can affect […]

Large COVID autopsy study finds SARS-CoV-2 all over the human body

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By Rich Haridy January 04, 2023 Source: National Institute of Allergy and Infectious Diseases A study found traces of the SARS-CoV-2 virus in over 80 different sites in the body In the most comprehensive autopsy tissue study conducted to date, researchers have found traces of the SARS-CoV-2 virus throughout the entire body, from the brain and the […]