Antibody dependent enhancement: Unavoidable problems in vaccine development

Authors: Lele Xu, Zhiqian Ma, Yang Li, Zhaoxia Pang, and Shuqi Xiao* Adv Immunol. 2021; 151: 99–133.Published online 2021 Sep 4. doi: 10.1016/bs.ai.2021.08.003 PMCID: PMC8438590PMID: 34656289 Abstract In some cases, antibodies can enhance virus entry and replication in cells.…[...]

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Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data

Authors: Flor M. Munoz,a,⁎Jakob P. Cramer,bCornelia L. Dekker,cMatthew Z. Dudley,dBarney S. Graham,eMarc Gurwith,fBarbara Law,gStanley Perlman,hFernando P. Polack,iJonathan M. Spergel,jEva Van Braeckel,kBrian J. Ward,lArnaud M. Didierlaurent,mPaul Henri Lambert,m and for the Brighton…[...]

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SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

Authors: Hui Jiang1,2,* and Ya-Fang Mei2,* Viruses. 2021 Oct; 13(10): 2056.Published online 2021 Oct 13. doi: 10.3390/v13102056 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely…[...]

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