Category: Lung

SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

Julian Gonzalez-Rubio1 Vu Thuy Khanh Le-Trilling2 Lea Baumann1 Maria Cheremkhina1 Hannah Kubiza1 Anja E. Luengen1,3 Sebastian Reuter3 Christian Taube3 Stephan Ruetten4 Daniela Duarte Campos5 Christian G. Cornelissen1,6 Mirko Trilling2 Anja Lena Thiebes1, Front. Bioeng. Biotechnol., 02 November 2023 Sec. Tissue Engineering and Regenerative MedicineVolume 11 – 2023 | https://doi.org/10.3389/fbioe.2023.1268782 Introduction: The Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, enters the […]

SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

Julian Gonzalez-Rubio1* Vu Thuy Khanh Le-Trilling2 Lea Baumann1 Maria Cheremkhina1 Hannah Kubiza1 Anja E. Luengen1, 3 Sebastian Reuter3 Christian Taube3 Stephan Ruetten4 Daniela Duarte Campos5 Christian Cornelissen6 Mirko Trilling2 Anja Lena Thiebes1* Front. Bioeng. Biotechnology. , Sec. Tissue Engineering and Regenerative Medicine, Volume 11 – 2023 | doi: 10.3389/fbioe.2023.1268782 The Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, enters the […]

Spectrum of Fibrotic Lung Diseases

Posted on | Posted on John Murphy | Leave a Comment on Spectrum of Fibrotic Lung Diseases

Marlies Wijsenbeek, M.D., and Vincent Cottin, M.D.  New England Journal of Medicine 2023 Diffuse parenchymal lung diseases encompass a large number of conditions, with a wide range of causes, clinical manifestations, and imaging and pathological features, as well as variable outcomes. Despite the intrinsic heterogeneity of this group of diseases, in most of them, the […]

Unraveling long COVID: Here’s what scientists who study the illness want to find out

Posted on | Posted on John Murphy | Leave a Comment on Unraveling long COVID: Here’s what scientists who study the illness want to find out

September 9, 2023, By Will Stone NPR Newsletter Researchers looking for root causes of long COVID work in the autopsy suite inside the Clinical Center at the National Institute of Health in Bethesda, Maryland. Valerie Plesch/Bloomberg via Getty Images For people suffering from long COVID’s often disabling symptoms, including intense fatigue, breathing troubles, cognitive issues and heart […]

Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

Posted on | Posted on John Murphy | Leave a Comment on Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

Suo-wen Xu, Iqra Ilyas & Jian-ping Weng  Acta Pharmacologica Sinica volume 44, pages695–709 (2023) Cite this article 17 October 2022 Abstract The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However, the pathophysiology of acute and post-acute manifestations of COVID-19 (long COVID-19) is understudied. Endothelial cells are sentinels lining the innermost layer of blood vessel that […]

Long Covid: MRI scans reveal new clues to symptoms

Posted on | Posted on John Murphy | Leave a Comment on Long Covid: MRI scans reveal new clues to symptoms

September 24, 2023 By Dominic Hughes, Health correspondent, BBC News People living with long Covid after being admitted to hospital are more likely to show some damage to major organs, according to a new study. MRI scans revealed patients were three times more likely to have some abnormalities in multiple organs such as the lungs, […]

UK scientists find link between proteins related to blood clots and long Covid

Posted on | Posted on John Murphy | Leave a Comment on UK scientists find link between proteins related to blood clots and long Covid

Biomarker discovery indicates that sufferers from brain fog and fatigue post-virus could be treated with anticoagulants Oksana Pyzik 31 Aug 2023 The Guardian Scientists have identified molecular signatures in the blood that are linked to brain fog, other cognitive problems and fatigue in patients who are diagnosed with long Covid after catching the virus. Raised levels of […]

Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis

Posted on | Posted on John Murphy | Leave a Comment on Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis

Kenji Hashimoto, Molecular Psychiatry (2023) Published: 04 July 2023 Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public health burden worldwide. In addition to respiratory, heart, and gastrointestinal symptoms, patients infected with SARS-CoV-2 experience a number of persistent neurological and psychiatric symptoms, known as […]

Large COVID autopsy study finds SARS-CoV-2 all over the human body

Posted on | Posted on John Murphy | Leave a Comment on Large COVID autopsy study finds SARS-CoV-2 all over the human body

By Rich Haridy January 04, 2023 Source: National Institute of Allergy and Infectious Diseases A study found traces of the SARS-CoV-2 virus in over 80 different sites in the body In the most comprehensive autopsy tissue study conducted to date, researchers have found traces of the SARS-CoV-2 virus throughout the entire body, from the brain and the […]

COVID-19 Lung Damage

Posted on | Posted on John Murphy | Leave a Comment on COVID-19 Lung Damage

Panagis Galiatsatos, M.D., M.H.S.  February 28, 2022  John’s Hopkins Like other respiratory illnesses, COVID-19 can cause lasting lung damage.  “As we continue to learn about COVID-19, we’re understanding more regarding how it affects the lungs during acute illness and afterward. And this is especially true with the virus’ ongoing variants, as well,” Galiatsatos says. What […]