Massive 23andMe survey reveals who may be at the highest risk for long COVID


Authors: Amy Graff, SFGATE May 31, 2022 It’s a question everyone wants answered: Who is more likely to develop long COVID-19, the debilitating symptoms that can linger for weeks, months or even longer, after an infection? A new unpublished study from 23andMe is part of a growing body of research shedding light on who experiences post-COVID conditions and why. […]

Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs


Authors: Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu Ma Jowaly Schneider, et al. Published:January 12, 2022DOI:https://doi.org/10.1016/j.ebiom.2022.103812 Background Thromboembolism is a life-threatening manifestation of coronavirus disease 2019 (COVID-19). We investigated a dysfunctional phenotype of vascular endothelial cells in the lungs during COVID-19. Methods We obtained the lung specimens from the patients […]

Study Finds Teenage Boys Six Times More Likely To Suffer Heart Problems From Vaccine Than Be Hospitalized by COVID


Authors; Paul Joseph Watson via Summit News, Research conducted by the University of California has found that teenage boys are six times more likely to suffer from heart problems caused by the COVID-19 vaccine than to be hospitalized as a result of COVID-19 itself. “A team led by Dr Tracy Hoeg at the University of California […]

Characteristics of SARS-CoV-2 and COVID-19


Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi  Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we […]

Primed” for Infection: Cells Damaged by Chronic Lung Disease Can Result in Severe COVID


Authors: TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases. The results of a study by an international scientific team co-led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that — like pouring water atop […]

Simplifying Covid-19 Into One Mechanism: The Epithelial-endothelial Crosstalk


The Multifaceted Covid-19 We see all imaginable symptoms with Covid-19, which is supposed to be a pneumonia disease. Yet Covid-19 can affect the brain, peripheral nerves, olfaction, taste, throat, thyroid, liver, gastrointestinal tract, kidneys, spleen, semen, skin, blood vessels, toes, and probably more to come. It’s intriguing how one virus, SARS-CoV-2, could cause so many symptoms. Is there actually a unifying mechanism of disease progression that could explain most […]

COVID-19 Autopsies Put Endothelial Damage, Angiogenesis in the Spotlight


More autopsy reports on COVID-19 patients, some from the United States, are helping researchers piece together a picture of a virus that damages endothelial cells, causing a clotting disorder that can lead to deep vein thrombosis and pulmonary emboli. “These people are in a hypercoagulant state, and early anticoagulation is important,” said Louis Maximilian Buja, […]