Three-year outcomes of post-acute sequelae of COVID-19


Miao Cai, , Yan Xie, Eric J. Topol & Ziyad Al-Aly Nature Medicine volume 30, pages1564–1573 (2024) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) in many organ systems. Risks of these sequelae have been characterized up to 2 years after infection, but longer-term follow-up is limited. Here we built a cohort of 135,161 […]

POST-ACUTE SEQUELAE OF COVID-19: CHARACTERIZATION, COMORBIDITIES, AND BIOMARKERS IN A DIVERSE COHORT


Emily Struttmann, Anish Shah, Matthew Moreida, et. al. doi: https://doi.org/10.1101/2024.06.20.24308901 Abstract Introduction Post-acute sequelae of COVID-19 (PASC) is causing a silent pandemic in the U.S. Gulf South, a part of flyover U.S. where patients are quietly withdrawing from the workforce and largely disconnected from the advocacy resources growing in more affluent regions[1]. To date, there is no clinical test to diagnose PASC […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches


Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2 , et. al., Front. Immunol., 03 March 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1344086 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant […]

Pathophysiological, immunological, and inflammatory features of long COVID


Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1 , et. al., Front. Immunol., 27 February 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have […]

The Long-term Cardiovascular Impact of COVID-19


Coronavirus (COVID-19) | January 22, 2021 | Dave Fornell, Editor DAIC Evidence suggests COVID long-haulers may have lingering cardiac impacts from their coronavirus infections Cardiologists are taking a closer look at the possible long-term cardiovascular effects on COVID long-hauler patients who still show symptoms long after they should be recovered from the virus. Getty Images “So this […]

Persistent Brainstem Dysfunction in Long-COVID: A Hypothesis


Shin Jie Yong PMID: 33538586 DOI: 10.1021/acschemneuro.0c00793 ACS Chem Neuroscience . 2021 Feb 17;12(4):573-580. doi: 10.1021/acschemneuro.0c00793. Epub 2021 Feb 4. Abstract Long-COVID is a postviral illness that can affect survivors of COVID-19, regardless of initial disease severity or age. Symptoms of long-COVID include fatigue, dyspnea, gastrointestinal and cardiac problems, cognitive impairments, myalgia, and others. While the possible causes of long-COVID include […]

Exercise is the Most Important Medicine for COVID-19


Torres, Georgia PhD; Constantinou, Demitri MBChB, FACSM; Gradidge, Philippe PhD; Patel, Deepak MD; Patricios, Jon MBBCh, MMedSci Current Sports Medicine Reports 22(8):p 284-289, August 2023. | DOI: 10.1249/JSR.0000000000001092 Abstract COVID-19 infection and long COVID affect multiple organ systems, including the respiratory, cardiovascular, renal, digestive, neuroendocrine, musculoskeletal systems, and sensory organs. Exerkines, released during exercise, have a potent crosstalk effect […]

Doctor’s Checklist for Treating Long COVID Patients


Written by Hallie Levine April 4, 2023 Lisa McCorkell had a mild bout of COVID-19 in March 2020. Young and healthy, she assumed that she would bounce back quickly. But when her fatigue, shortness of breath, and brain fog persisted, she realized that she most likely had long COVID.  “Back then, we as patients basically coined […]

Even mild cases of COVID-19 can lead to long-term health problems, study finds


A new study published in the journal Nature Medicine has found that even mild cases of COVID-19 can lead to an increased risk of long-term health problems two years later. The study, which was conducted by researchers at the Washington University School of Medicine in St. Louis, looked at data from nearly 139,000 military veterans […]

High cholesterol, overweight and reduced physical stamina are long COVID sequelae in young adults


Authors: University of Zurich Summary: 6, 2022:Science Daily As the Covid-19 pandemic evolves, the issue of post-infection consequences is growing in significance. Does Long Covid impact previously healthy young adults? Although this group is of great societal importance, representing the next generation and the backbone of the workforce, the intermediate-term and long-term effects of SARS-CoV-2 […]