Authors: Yujun Tang,† Jiajia Liu,† Dingyi Zhang, Zhenghao Xu, Jinjun Ji,* and Chengping Wen* Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the […]
SARS-CoV-2 infection: The role of cytokines in COVID-19 disease
Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of […]
Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment
Authors: Mehmet Soy 1, Gökhan Keser 2, Pamir Atagündüz 3, Fehmi Tabak 4, Işık Atagündüz 5, Servet Kayhan COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes only mild symptoms in the majority of the cases, […]
In the lab, scientists identify possible COVID-19 treatment
Authors: St. Jude Children’s Research Hospital The COVID-19 pandemic continues to cause significant illness and death while treatment options remain limited. St. Jude Children’s Research Hospital scientists have discovered a […]
Accumulating evidence suggests anti-TNF therapy needs to be given trial priority in COVID-19 treatment
Authors: Philip C Robinson, Duncan Richards, Helen L Tanner, Marc Feldmann The COVID-19 pandemic continues to wreak havoc on global health-care systems and to claim an increasing number of lives. […]
TNF Biologics and COVID-19: What Autoimmune Patients Need to Know
Authors: If you’re taking a type of medication known as tumor necrosis factor inhibitors, also called anti-TNF or TNFis, you may be wondering how these drugs could impact your chances […]
Pathways in the Pathophysiology of Coronavirus 19 Lung Disease Accessible to Prevention and Treatment
Authors: Michael Eisenhut 1, Jae Il Shin 2 Background: In COVID 19 related lung disease, which is a leading cause of death from this disease, cytokines like tumor necrosis factor-alpha (TNF alpha) may be […]
Integrative clinical, genomics and metabolomics data analysis for mainstream precision medicine to investigate COVID-19
Authors: Zeeshan Ahmed, Saman Zeeshan, David J Foran, Lawrence C Kleinman, Fredric E Wondisford, XinQi Dong Crrespondence to Dr Zeeshan Ahmed, Rutgers Institute for Health, Health Care Policy and Aging Research, Rutgers University, […]
8 tools that helped us tackle the coronavirus
Authors: Ryan Cross , Laura Howes , Megha Satyanarayana ADENOVIRAL VECTORS Viruses might be nature’s most efficient gene-delivery vehicles. At its essence, a virus is simply a package that shuttles genes into a host cell, which […]
Genomics study identifies routes of transmission of coronavirus in care homes
Authors: Craig Brierley, University of Cambridge Genomic surveillance—using information about genetic differences between virus samples—can help identify how SARS-CoV-2 spreads in care home settings, whose residents are at particular risk, according […]