Maura Boldrini, MD, PhD1,2; Peter D. Canoll, MD, PhD3; Robyn S. Klein, MD, PhD4,5,6, JAMA Psychiatry. 2021;78(6):682-683. doi:10.1001/jamapsychiatry.2021.0500 COVID-19 has resulted in more than 120 million cases and 2.6 million deaths to date. Respiratory and gastrointestinal symptoms are accompanied […]
Dynamic Assessment of Hematological Parameters as Predictive Biomarkers for Disease Severity and Prognosis in COVID-19 Patients: A Longitudinal Study
Aparna P. Patange • Jabbar V. Desai • Bhupal Pujari • Aparna Marwah • Animesh Dey, Published: July 01, 2024, DOI: 10.7759/cureus.63593 Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has […]
Possible Long Covid Cause Identified: Suggests Protein Might Be Culprit—And Medication Might Cure It
Arianna Johnson,,Forbes Staff.Feb 21, 2024,02 Researchers have potentially linked an antiviral protein produced by the body during infection as the cause of long Covid, according to a new study, and […]
Why don’t most children get severely sick from COVID? Nose and immune response offer clues
By David Olson, October 23, 2023 10:50 Newsday Young children rarely get severely ill from COVID-19 because their immune systems seem to block the coronavirus from spreading beyond the nose, a […]
The characteristics and evolution of pulmonary fibrosis in COVID-19 patients as assessed by AI-assisted chest HRCT
Authors: Jia-Ni Zou , Liu Sun , Bin-Ru Wang , You Zou , Shan Xu, Yong-Jun Ding, Li-Jun Shen, Wen-Cai Huang, Xiao-Jing Jiang, Shi-Ming Chen Published: March 23, 2021 https://doi.org/10.1371/journal.pone.0248957 Abstract The characteristics and […]
Multi-layered transcriptomic analyses reveal an immunological overlap between COVID-19 and hemophagocytic lymphohistiocytosis associated with disease severity
Authors: Lena F. Schimkea,5, Alexandre H.C. Marquesa, Gabriela Crispim Baiocchia, Caroline Aliane de Souza Pradob Dennyson Leandro M. Fonsecab , Paula Paccielli Freirea , Desirée Rodrigues Plaçab , Igor Salerno […]
Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider
Authors: Aurélie Najm1, http://orcid.org/0000-0003-1105-5640Alessia Alunno2, Xavier Mariette3,4, http://orcid.org/0000-0001-6612-7336Benjamin Terrier5,6, http://orcid.org/0000-0003-2406-161XGabriele De Marco7,8, Jenny Emmel9, Laura Mason9, Dennis G McGonagle7,10 and http://orcid.org/0000-0002-8411-7972Pedro M Machado11,12,13 Abstract Background The SARS-CoV-2 pandemic is a global health problem. Beside the specific pathogenic effect of SARS-CoV-2, […]
Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and In-Hospital Mortality
Authors: Bandar Alosaimi1,2, Ayman Mubarak3, Maaweya E. Hamed3, Abdullah Z. Almutairi4, Ahmed A. Alrashed5, Abdullah AlJuryyan6, Mushira Enani7,Faris Q. Alenzi8 and Wael Alturaiki9* COVID-19 severity due to innate immunity dysregulation accounts for prolonged hospitalization, critical complications, and mortality. […]
Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy
Authors: Jun Zhang 1, Kristen M Tecson 1, Peter A McCullough 1 2 3 Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019 (COVID-19). There is growing evidence to suggest that the angiotensin […]
Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Authors: Yujun Tang,† Jiajia Liu,† Dingyi Zhang, Zhenghao Xu, Jinjun Ji,* and Chengping Wen* Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the […]