Neurological manifestations of post-acute sequelae of COVID-19: which liquid biomarker should we use?


Dominique Comeau1† Mykella Martin2† Gilles A. Robichaud3,4,5 Ludivine Chamard-Witkowski2,6*1Dr. Georges-L. Long COVID syndrome, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent symptoms lasting 3–12 weeks post SARS-CoV-2 infection. Patients suffering…[...]

Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain


Héctor Hernández-Parra1,2 Octavio Daniel Reyes-Hernández3 Gabriela Figueroa-González4 Manuel González-Del Carmen5 Maykel González-Torres6 Sheila I. Peña-Corona2 Benjamín Florán7 Hernán Cortés8* Gerardo Leyva-Gómez2* https://pubmed.ncbi.nlm.nih.gov/36998270/ Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease (COVID-19), including stroke, ataxia, meningitis,…[...]

Skin reactions to COVID-19 vaccines?  


2020-January 18 The coronavirus disease 2019 (COVID-19) pandemic has led to the development and approval of vaccines against the responsible virus — severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). More than 100 companies and institutions worldwide have developed vaccine…[...]

Toxic Epidermal Necrolysis Post COVID-19 Vaccination – First Reported Case


Authors: Mohamad Bakir, Hanan Almeshal, Rifah Alturki, Sulaiman Obaid, Areej Almazroo Published: August 16, 2021 Abstract Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of acute, delayed-type hypersensitivity reactions that affect the skin and the…[...]

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease


Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of…[...]

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment


Authors: Mehmet Soy 1, Gökhan Keser 2, Pamir Atagündüz 3, Fehmi Tabak 4, Işık Atagündüz 5, Servet Kayhan COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes only mild symptoms in the majority of the cases,…[...]

Accumulating evidence suggests anti-TNF therapy needs to be given trial priority in COVID-19 treatment


Authors: Philip C Robinson, Duncan Richards, Helen L Tanner, Marc Feldmann The COVID-19 pandemic continues to wreak havoc on global health-care systems and to claim an increasing number of lives.…[...]

Pathways in the Pathophysiology of Coronavirus 19 Lung Disease Accessible to Prevention and Treatment


Authors: Michael Eisenhut 1, Jae Il Shin 2 Background: In COVID 19 related lung disease, which is a leading cause of death from this disease, cytokines like tumor necrosis factor-alpha (TNF alpha) may be…[...]