Category: Encephalomyelitis

SARS-COV-2 a trigger of myelin oligodendrocyte glycoprotein-associated disorder

Posted on | Posted on John Murphy | Leave a Comment on SARS-COV-2 a trigger of myelin oligodendrocyte glycoprotein-associated disorder

Authors: Magnus Johnsson,Fredrik Asztely, et. al. June 2022 Annals of Clinical and Translational Neurology Abstract SARS-COV-2 frequently cause neurological disorders and is sometimes associated with onset of autoimmune diseases affecting the nervous system. Over recent years, a rare but distinct diagnosis designated myelin oligodendrocyte glycoprotein-associated disorder (MOGAD) has been recognized in patients with attacks of […]

Pathophysiology, diagnosis, and management of neuroinflammation in covid-19

Posted on | Posted on John Murphy | Leave a Comment on Pathophysiology, diagnosis, and management of neuroinflammation in covid-19

BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-073923 (Published 18 August 2023)Cite this as: BMJ 2023;382:e073923, Rachel L Brown123,  Laura Benjamin24,  Michael P Lunn12,  Tehmina Bharucha25,  Michael S Zandi12,  Chandrashekar Hoskote6,  Patricia McNamara2,  Hadi Manji1 Abstract Although neurological complications of SARS-CoV-2 infection are relatively rare, their potential long term morbidity and mortality have a significant impact, given the large numbers of infected patients. Covid-19 is […]

Study in Mice Suggests that COVID-19 Increases Risk of Developing Parkinson’s Disease

Posted on | Posted on John Murphy | Leave a Comment on Study in Mice Suggests that COVID-19 Increases Risk of Developing Parkinson’s Disease

Thomas Jefferson University May 18, 2022 New research finds that the novel coronavirus can make the mouse brain more susceptible to a toxin that induces nerve-cell loss seen in Parkinson’s. PHILADELPHIA – Brain fog, headaches, insomnia are some of the neurological symptoms doctors have observed in COVID-19 patients. Neurological sequelae after a viral infection is not […]

Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

Posted on | Posted on John Murphy | Leave a Comment on Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

Héctor Hernández-Parra1,2 Octavio Daniel Reyes-Hernández3 Gabriela Figueroa-González4 Manuel González-Del Carmen5 Maykel González-Torres6 Sheila I. Peña-Corona2 Benjamín Florán7 Hernán Cortés8* Gerardo Leyva-Gómez2* https://pubmed.ncbi.nlm.nih.gov/36998270/ Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease (COVID-19), including stroke, ataxia, meningitis, encephalitis, and cognitive impairment. These alterations can cause serious sequelae or death and are associated with the entry of SARS-CoV-2 into the Central Nervous System […]

Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Posted on | Posted on John Murphy | Leave a Comment on Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Published online 2021 Dec 24. doi: 10.3390/medicina58010028 PMCID: PMC8778312 PMID: 350563 C. (Linda) M. C. van Campen,1,* Peter C. Rowe,2 and Frans C. Visser1 Olli J. Polo, Academic Editor Abstract Background and Objectives: Symptoms and hemodynamic findings during orthostatic stress have been reported in both long-haul COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), but little work has directly compared patients from these two […]

COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside

Posted on | Posted on John Murphy | Leave a Comment on COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside

npj Parkinson’s Disease volume 6, Article number: 18 (2020) Cite this article Abstract This Viewpoint discusses insights from basic science and clinical perspectives on coronavirus disease 2019 (COVID-19)/severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection in the brain, with a particular focus on Parkinson’s disease. Major points include that neuropathology studies have not answered the central issue of whether the virus enters central […]

A Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination againstCOVID-19

Posted on | Posted on John Murphy | Leave a Comment on A Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination againstCOVID-19

Authors: Michael Mörz Abstract: The current report presents the case of a 76-year-old man with Parkinson’s disease (PD)who died three weeks after receiving his third COVID-19 vaccination. The patient was first vac-cinated in May 2021 with the ChAdOx1 nCov-19 vector vaccine, followed by two doses of theBNT162b2 mRNA vaccine in July and December 2021. The […]

New research provides insight into Long COVID and ME

Posted on | Posted on John Murphy | Leave a Comment on New research provides insight into Long COVID and ME

Authors: University of Otago July 12, 2022: Science Daily Summary: Researchers have uncovered how post-viral fatigue syndromes, including Long COVID, become life-changing diseases and why patients suffer frequent relapses. Arising commonly from a viral infection, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), is known to cause brain-centred symptoms of neuroinflammation, loss of homeostasis, brain fog, lack of […]

Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms

Posted on | Posted on John Murphy | Leave a Comment on Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms

Authors: Amy D. Proal1 and Michael B. VanElzakker1,2* The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients who sustain an acute SARS-CoV-2 infection are developing a wide range of persistent symptoms that do not resolve over the course of many […]