Category: Blood brain barrier

New-Onset Seizures and Seizure Worsening in the Course of COVID-19 Infection

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Ekaterina Viteva, Published: July 04, 2024, DOI: 10.7759/cureus.63868  Abstract Introduction: The aim of our study is to assess the clinical manifestations, investigation results, and outcomes in Bulgarian patients with seizures in the course of COVID-19 infection. Methods: We performed an open, prospective study during a 12-month period from January 2021 with the participation of 290 inpatients and outpatients […]

The Neurological Implications of COVID-19: A Comprehensive Narrative Review

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Ithamar Cheyne • Venmanassery Sreejan Gopinath • Neeharika Muppa , et. al., May 15, 2024, DOI: 10.7759/ cureus.60376  Abstract The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 revealed a huge number of problems as well as discoveries in medicine, notably, regarding the effects of the virus on the central nervous system (CNS) and peripheral nervous system (PNS). This paper is a narrative […]

Pain, fatigue, fuzzy thinking: How long COVID disrupts the brain

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NOVEMBER 2023, Jon Hamilton, NPR Scientists are learning more about how long COVID affects the brain. Michelle Wilson got COVID three years ago. She’s still waiting for her brain and nervous system to recover. Wilson’s memory is spotty, she’s frequently in pain, and even a short walk leaves her exhausted. “I actually bought a cane […]

Study in Mice Suggests that COVID-19 Increases Risk of Developing Parkinson’s Disease

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Thomas Jefferson University May 18, 2022 New research finds that the novel coronavirus can make the mouse brain more susceptible to a toxin that induces nerve-cell loss seen in Parkinson’s. PHILADELPHIA – Brain fog, headaches, insomnia are some of the neurological symptoms doctors have observed in COVID-19 patients. Neurological sequelae after a viral infection is not […]

Disruption of the blood-brain barrier due to long COVID

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Bhavana Kunkalikar Jan 27 2023 Reviewed by Aimee Molineux, https://doi.org/10.21203/rs.3.rs-2069710/v2 In a recent study posted to the Research Square* preprint server, researchers explored the destruction of the blood-brain barrier (BBB) due to cognitive impairment associated with long coronavirus disease (COVID). Background Studies have demonstrated microvascular injuries observed in the brains of deceased severe acute respiratory syndrome coronavirus 2 […]

Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

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Héctor Hernández-Parra1,2 Octavio Daniel Reyes-Hernández3 Gabriela Figueroa-González4 Manuel González-Del Carmen5 Maykel González-Torres6 Sheila I. Peña-Corona2 Benjamín Florán7 Hernán Cortés8* Gerardo Leyva-Gómez2* https://pubmed.ncbi.nlm.nih.gov/36998270/ Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease (COVID-19), including stroke, ataxia, meningitis, encephalitis, and cognitive impairment. These alterations can cause serious sequelae or death and are associated with the entry of SARS-CoV-2 into the Central Nervous System […]

COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside

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David Sulzer, Angelo Antonini, Valentina Leta, Anna Nordvig, Richard J. Smeyne, James E. Goldman, Osama Al-Dalahmah, Luigi Zecca, Alessandro Sette, Luigi Bubacco, Olimpia Meucci, Elena Moro, Ashley S. Harms, Yaqian Xu, Stanley Fahn & K. Ray Chaudhuri  npj Parkinson’s Disease volume 6, Article number: 18 (2020) Cite this article Abstract This Viewpoint discusses insights from basic science and clinical perspectives on coronavirus disease 2019 (COVID-19)/severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection in the brain, with a particular focus […]

Scientists begin to untangle how COVID-19 affects brain cells

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by The Francis Crick Institute, AUGUST 7, 2023 Researchers at the Francis Crick Institute have shown in lab-based experiments that variants of SARS-CoV-2, the virus that causes COVID-19, can affect the blood-brain barrier and damage brain cells in different ways. This work gives clues as to how the virus could enter the brain, but doesn’t take […]

Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments

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The causes of long COVID, which disables millions, may come together in the brain and nervous system  Stephani Sutherland   March 1, 2023 Tara Ghormley has always been an overachiever. She finished at the top of her class in high school, graduated summa cum laude from college and earned top honors in veterinary school. She went […]