Endothelial cell damage is the central part of COVID-19 and a mouse model
induced by injection of the S1 subunit of the spike protein


Authors: Gerard J. NuovoCynthia MagroToni ShafferHamdy AwadDavid SusterSheridan MikhailBing HeJean-Jacques MichailleBenjamin LiechtyEsmerina Tili Annals of Diagnostic Pathology ABS T R A C TNeurologic complications of symptomatic COVID-19 are common. Brain tissues from 13 autopsies of people who died of COVID-19 were examined. Cultured endothelial and neuronal cells were incubated with and wild type mice were […]

Prevalence and patterns of symptoms of dysautonomia in patients with long-COVID syndrome: A cross-sectional study


Authors: Ahmed M. Eldokla,Aliae A. Mohamed-Hussein, Ahmed M. Fouad, et. al. 08 Annals of Clinical and Translational Neurology Volume 9, Issue 6 p. 778-785 Abstract Background The association between autonomic dysfunction and long-COVID syndrome is established. However, the prevalence and patterns of symptoms of dysautonomia in long-COVID syndrome in a large population are lacking. Objective To […]

COVID-19 Presenting as Encephalitis and Myopericarditis: A Report of a Rare Case


Nikolaos Kakaletsis • Ioannis Alevroudis • Serafeim-Chrysovalantis Kotoulas •et. al., Published: June 10, 2024, DOI: 10.7759/cureus.62056  Abstract COVID-19 might present with a wide range of clinical manifestations, from mild respiratory distress to severe multi-organ dysfunction. We present a unique case of complex COVID-19 presentation in a 45-year-old female who initially developed general symptoms such as fever, cough, headache, and weakness, which escalated […]

Long COVID’s Unique Neural Impact


Co-authors are Jonas A. Hosp, M.D., Nils Schroter, M.D., Marco Reisert, Ph.D., Horst Urbach, M.D., Cornelius Weiller, M.D., and Elias Kellner, Ph.D Neurology Neuroscience, November 22, 2023 Summary: A new study reveals distinct brain changes in long COVID patients compared to those fully recovered from COVID-19 and healthy controls. The research employed Diffusion Microstructure Imaging (DMI) […]

Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments


The causes of long COVID, which disables millions, may come together in the brain and nervous system BY STEPHANI SUTHERLAND, MARCH 1, 2023 March 2023 Neuroscience Tara Ghormley has always been an overachiever. She finished at the top of her class in high school, graduated summa cum laude from college and earned top honors in veterinary […]

Evolution of neurologic symptoms in non-hospitalized COVID-19 “long haulers”


Authors: Sareen T. Ali,Anthony K. Kang,Tulsi R. Patel,Jeffrey R. Clark, et. al. ,May 2022 Annals of Clinical and Translational Neurology Abstract Objective We characterized the evolution of neurologic symptoms and self-perceived recovery of non-hospitalized COVID-19 “long haulers” 6–9 months after their initial Neuro-COVID-19 clinic evaluation. Methods In this follow-up study on the first 100 patients, 50 […]

Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome


N. Azcue, R. Del Pino, et. al., Journal of Translational Medicine volume 21, Article number: 814 (2023)  Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and post-COVID condition can present similarities such as fatigue, brain fog, autonomic and neuropathic symptoms. Methods The study included 87 patients with post-COVID condition, 50 patients with ME/CFS, and 50 healthy controls (HC). The hemodynamic autonomic function was […]

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization


Maxime Taquet, Zuzanna Skorniewska, Adam Hampshire, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Parisa Mansoori, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, PHOSP-COVID Study Collaborative Group,  Nature Medicine (August 2023)  Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and […]

Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases


Carl Gunnar Gottschalk, Daniel Peterson, Jan Armstrong, Konstance Knox & Avik Roy  Infectious Agents and Cancer volume 18, Article number: 7 (2023) Cite this article, A Correction to this article was published on 24 April 2023 Abstract Historically, COVID-19 emerges as one of the most devastating diseases of humankind, which creates an unmanageable health crisis worldwide. Until now, this disease costs millions of lives and continues to paralyze […]